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Test Catalog

Test ID: PCDES    
Pediatric Autoimmune Central Nervous System Disorders Evaluation, Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluating children with autoimmune central nervous system disorders using serum specimens

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
PCSIPeds Autoimmune CNS Interp, SNoYes
GANGAChR Ganglionic Neuronal Ab, SNoYes
ANN1SAnti-Neuronal Nuclear Ab, Type 1NoYes
CS2CSCASPR2-IgG CBA, SNoYes
DPPISDPPX Ab IFA, SNoYes
GABCSGABA-B-R Ab CBA, SNoYes
GD65SGAD65 Ab Assay, SYesYes
GFAISGFAP IFA, SNoYes
LG1CSLGI1-IgG CBA, SNoYes
GL1ISmGluR1 Ab IFA, SNoYes
MOGFSMOG FACS, SYesYes
NMDCSNMDA-R Ab CBA, SNoYes
NMOFSNMO/AQP4 FACS, SYesYes
CCNN-Type Calcium Channel AbNoYes
CCPQP/Q-Type Calcium Channel AbNoYes
PCATRPurkinje Cell Cytoplasmic Ab Type TrNoYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
AGN1SAnti-Glial Nuclear Ab, Type 1NoNo
AGNBSAGNA-1 Immunoblot, SNoNo
AMIBSAmphiphysin Immunoblot, SNoNo
AMPCSAMPA-R Ab CBA, SNoNo
AMPHSAmphiphysin Ab, SNoNo
AMPISAMPA-R Ab IF Titer Assay, SNoNo
AN1BSANNA-1 Immunoblot, SNoNo
AN2BSANNA-2 Immunoblot, SNoNo
ANN2SAnti-Neuronal Nuclear Ab, Type 2NoNo
ANN3SAnti-Neuronal Nuclear Ab, Type 3NoNo
DPPCSDPPX Ab CBA, SNoNo
DPPTSDPPX Ab IFA Titer, SNoNo
GFACSGFAP CBA, SNoNo
GFATSGFAP IFA Titer, SNoNo
GL1CSmGluR1 Ab CBA, SNoNo
GL1TSmGluR1 Ab IFA Titer, SNoNo
MOGTSMOG FACS Titer, SNoNo
NMDISNMDA-R Ab IF Titer Assay, SNoNo
NMOTSNMO/AQP4 FACS Titer, SNoNo
PC1BSPCA-1 Immunoblot, SNoNo
PCAB2Purkinje Cell Cytoplasmic Ab Type 2NoNo
PCABPPurkinje Cell Cytoplasmic Ab Type 1NoNo
PCTBSPCA-Tr Immunoblot, SNoNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If indirect immunofluorescence assay (IFA) patterns suggest ANNA-1 antibody, then ANNA-1 Immunoblot and ANNA-2 Immunoblot are performed at an additional charge.

 

If IFA patterns suggest ANNA-2 antibody, then ANNA-2 immunoblot, ANNA-1 immunoblot, and ANNA-2 antibody IFA are performed at an additional charged.

 

If IFA patterns suggest ANNA-3 antibody, then ANNA-3 IFA is performed at an additional charge.

 

If IFA patterns suggest PCA-1 antibody, then PCA-1 immunoblot and PCA-1 IFA are performed at an additional charge.

 

If IFA patterns suggest PCA-2 antibody, then PCA-2 IFA is performed at an additional charge.

 

If IFA patterns suggest PCA-Tr antibody, then PCA-Tr immunoblot is performed at an additional charge.

 

If IFA patterns suggest AMPHI antibody, then AMPHI antibody IFA is performed at an additional charge.

 

If IFA patterns suggest amphiphysin antibody, then amphiphysin immunoblot and amphiphysin antibody IFA titer are performed at an additional charge.

 

If IFA pattern suggests NMDA-R antibody, then NMDA-R IFA titer is performed at an additional charge.

 

If IFA pattern suggests AMPA-R antibody, then AMPA-R antibody cell-binding assay (CBA) and AMPA-R IFA titer are performed at an additional charge.

 

If IFA pattern suggest GABA-B-R antibody, then GABA-B-R IFA titer is performed at an additional charge.

 

If IFA pattern suggest DPPX antibody, then DPPX antibody CBA and DPPX IFA titer are performed at an additional charge.

 

If IFA pattern suggest mGluR1 antibody, then mGluR1antibody CBA and mGluR1 IFA titer are performed at an additional charge.

 

If IFA pattern suggest GFAP antibody, then GFAP antibody CBA and GFAP IFA titer are performed at an additional charge.

 

If NMO/AQP4-IgG fluorescence-activated cell sorting (FACS) screen assay requires further investigation, then NMO/AQP4-IgG FACS titration assay is performed at an additional charge.

 

If MOG FACS screen assay requires further investigation, then MOG FACS titration assay is performed at an additional charge.

 

See Pediatric Autoimmune Central Nervous System Disorders Evaluation Algorithm-Serum in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

AMPCS, CS2CS, DPPCS, GABCS, GFACS, GL1CS, LG1CS, NMDCS: Cell-Binding Assay (CBA)

 

MOGFS, MOGTS, NMOFS, NMOTS: Flow Cytometry (FACS)

 

AMPHS, AGN1S, AMPIS, ANN1S, ANN2S, ANN3S, DPPIS, DPPTS, GFAIS, GFATS, GL1IS, GL1TS, NMDIS, PCAB2, PCABP, PCATR: Indirect Immunofluorescence (IFA)

 

CCN, CCPQ, GANG, GD65S: Radioimmunoassay (RIA)

 

AGNBS, AMIBS, AN1BS, AN2BS, PC1BS, PCTBS: Immunoblot (IB)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Peds Autoimmune CNS Eval, S

Aliases Lists additional common names for a test, as an aid in searching

Encephalitis
Myelitis
Encephalopathy
Myelopathy, pediatric
Myelopathy, child