Test Catalog

Test ID: AVWPR    
von Willebrand Disease Profile, Plasma

Useful For Suggests clinical disorders or settings where the test may be helpful

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity


Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3 (rare)


This test is not useful for detection of hemophilia carriers.

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
AVWPIvon Willebrand Disease Tech InterpNoYes
F8ACoag Factor VIII Activity Assay, PYesYes
VWAGvon Willebrand Factor Ag, PYesYes
VWACTvon Willebrand Factor Activity, PYesYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
F8ISCoag Factor VIII Assay Inhib Scrn,PNoNo
AVWPQvon Willebrand Disease InterpNoNo
VWFMPvon Willebrand Factor Multimer, PYes, (order VWFMS)No
RISTRistocetin Cofactor, PNoNo
8BETHFVIII Bethesda Units, PNoNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial testing includes: coagulation factor VIII activity assay, von Willebrand factor (VWF) antigen, VWF activity and interpretation. 


If the factor VIII, VWF antigen, VWF activity, and  VWF activity:VWF antigen ratio are normal, then a computer-generated interpretive comment indicating no evidence of von Willebrand disease will be provided.


If VWF activity assay is less than 55% or VWF activity:VWF antigen ratio is abnormally increased, then VWF ristocetin cofactor activity assay will be performed at an additional charge.


If VWF antigen is less than 55%, the VWF activity is less than 55%, or the VWF activity:VWF antigen ratio is abnormally low, then VWF multimer analysis will be performed at an additional charge.


If any test results are abnormal, all results will be reviewed by a coagulation consultant and a von Willebrand Disease Interpretation will be provided at an additional charge.


See von Willebrand Disease Profile in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

F8A: Optical Clot-Based

VWAG, VWACT: Latex Immunoassay (LIA)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

von Willebrand Disease Prof

Aliases Lists additional common names for a test, as an aid in searching

von Willebrand Profile