Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: PAC1
Paraneoplastic, Autoantibody Evaluation, Spinal Fluid
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Aids in the diagnosis of paraneoplastic neurological autoimmune disorders related to carcinoma of lung, breast, ovary, thymoma, or Hodgkin lymphoma in spinal fluid specimens
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PNEOI | Paraneoplastic Interpretation, CSF | No | Yes |
| AMPHC | Amphiphysin Ab, CSF | No | Yes |
| AGN1C | Anti-Glial Nuclear Ab, Type 1 | No | Yes |
| ANN1C | Anti-Neuronal Nuclear Ab, Type 1 | No | Yes |
| ANN2C | Anti-Neuronal Nuclear Ab, Type 2 | No | Yes |
| ANN3C | Anti-Neuronal Nuclear Ab, Type 3 | No | Yes |
| CRMC | CRMP-5-IgG, CSF | No | Yes |
| PCTRC | Purkinje Cell Cytoplasmc Ab Type Tr | No | Yes |
| PCA1C | Purkinje Cell Cytoplasmic Ab Type 1 | No | Yes |
| PCA2C | Purkinje Cell Cytoplasmic Ab Type 2 | No | Yes |
Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AGNBC | AGNA-1 Immunoblot, CSF | No | No |
| AMPCC | AMPA-R Ab CBA, CSF | No | No |
| AMPIC | AMPA-R Ab IF Titer Assay, CSF | No | No |
| AMIBC | Amphiphysin Immunoblot, CSF | No | No |
| AN1BC | ANNA-1 Immunoblot, CSF | No | No |
| AN2BC | ANNA-2 Immunoblot, CSF | No | No |
| CS2CC | CASPR2-IgG CBA, CSF | No | No |
| CRMWC | CRMP-5-IgG Western Blot, CSF | Yes | No |
| DPPCC | DPPX Ab CBA, CSF | No | No |
| DPPTC | DPPX Ab IFA Titer, CSF | No | No |
| DPPIC | DPPX Ab IFA, CSF | No | No |
| GABCC | GABA-B-R Ab CBA, CSF | No | No |
| GABIC | GABA-B-R Ab IF Titer Assay, CSF | No | No |
| GD65C | GAD65 Ab Assay, CSF | Yes | No |
| LG1CC | LGI1-IgG CBA, CSF | No | No |
| GL1CC | mGluR1 Ab CBA, CSF | No | No |
| GL1TC | mGluR1 Ab IFA Titer, CSF | No | No |
| GL1IC | mGluR1 Ab IFA, CSF | No | No |
| NMDCC | NMDA-R Ab CBA, CSF | No | No |
| NMDIC | NMDA-R Ab IF Titer Assay, CSF | No | No |
| PC1BC | PCA-1 Immunoblot, CSF | No | No |
| PCTBC | PCA-Tr Immunoblot, CSF | No | No |
| VGKCC | VGKC-complex Ab IPA, CSF | No | No |
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
If indirect immunofluorescence assay (IFA) pattern suggests AGNA-1 antibody, then AGNA-1 immunoblot is performed at an additional charge.
If IFA pattern suggests ANNA-1 antibody, then ANNA-1 immunoblot is performed at an additional charge.
If IFA pattern suggests ANNA-2 antibody, then ANNA-2 immunoblot is performed at an additional charge.
If IFA pattern suggests PCA-1 antibody, then PCA-1 immunoblot is performed at an additional charge.
If IFA pattern suggests PCA-Tr antibody, then PCA-Tr immunoblot is performed at an additional charge.
If IFA patterns suggest CRMP-5-IgG, then CRMP-5-IgG Western blot is performed at an additional charge.
If IFA patterns suggest GAD65 antibody, then GAD65 antibody radioimmunoassay (RIA) is performed at an additional charge.
If IFA patterns suggest neuronal voltage-gated potassium channel-complex (VGKC) autoantibody, then VGKC-complex antibody RIA is performed at an additional charge.
If VGKC-complex antibody RIA is greater than 0.00 nmol/L, then LGI1-IgG cell-binding assay (CBA) and CASPR2-IgG CBA are performed at an additional charge.
If IFA patterns suggest amphiphysin antibody, then amphiphysin immunoblot is performed at an additional charge.
If IFA pattern suggests NMDA-Receptor, then NMDA-Receptor antibody CBA and/or NMDA-Receptor titer is performed at an additional charge.
If IFA pattern suggests AMPA-Receptor, then AMPA-Receptor antibody CBA and/or AMPA-Receptor titer is performed at an additional charge.
If IFA pattern suggests GABA-B-Receptor, then GABA-B-Receptor antibody CBA and/or GABA-B-Receptor titer is performed at an additional charge.
If IFA pattern suggests DPPX, then DPPX antibody CBA and DPPX titer is performed at an additional charge.
If IFA pattern suggests mGluR1, then mGluR1 antibody CBA and mGluR1 titer is performed at an additional charge.
The following algorithms are available in Special Instructions.
Special Instructions Library of PDFs including pertinent information and forms related to the test
Method Name A short description of the method used to perform the test
AGN1C, AMPHC, AMPIC, ANN1C, ANN2C, ANN3C, CRMC, DPPIC, DPPTC, GABIC, GL1IC, GL1TC, NMDIC, PCA1C, PCA2C, PCTRC: Indirect Immunofluorescence Assay (IFA)
CRMWC: Western Blot
AGNBC, AMIBC, AN1BC, AN2BC, PC1BC, PCTBC: Immunoblot (IB)
GD65C, VGKCC: Radioimmunoassay (RIA)
AMPCC, CS2CC, DPPCC, GABCC, GL1CC, LG1CC, NMDCC: Cell-Binding Assay (CBA)
NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name Lists a shorter or abbreviated version of the Published Name for a test
Aliases Lists additional common names for a test, as an aid in searching
ANNA-1, CSF
ANNA-2, CSF
ANNA-3, CSF
Anti-Hu
Antineuronal
Cerebellar Antibodies
CRMP-5-IgG, CSF
Dorsal Root Ganglion Antibody
Hu Antibody
Neuron Restricted Autoantibodies
Neuronal Nuclear Antibody
Neuronal-Anti
Ovarian Cancer-Related Antibodies
Paraneoplastic Autoantibody Western Blot Confirmation, CSF
Paraneoplastic Neurological Autoimmunity
PCA-1, CSF
PCA-2, CSF
PCA-Tr, CSF
Purkinje Cell Cytoplasmic Antibodies
Ri, Anti
Yo-Anti