Test Catalog

Test ID: CAPN    
Solid Tumor-Targeted Cancer Gene Panel, Next-Generation Sequencing, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying solid tumors that may respond to targeted therapies by assessing multiple gene targets simultaneously


Identifying specific variants within genes known to be associated with response or resistance to specific cancer therapies


Identifying variants that may help determine prognosis for patients with solid tumors


Assisting in establishing a diagnosis (eg, KIT and PDGFRA alterations for gastrointestinal stromal tumors)


Aiding in the determination of clinical trial eligibility for patients with genetic variants not amenable to current FDA-approved targeted therapies


This test is not intended for use for hematological malignancies or assessment of germline variants

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test uses targeted next-generation sequencing to evaluate for somatic variants within 50 genes associated with cancer: ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, and VHL. See Targeted Gene Regions Interrogated by Solid Tumor Targeted Cancer Gene Panel by Next-Generation Sequencing in Special Instructions for details regarding the targeted gene regions identified by this test.

Additional Tests Lists tests that are always performed, at an additional charge, with the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
SLIRVSlide Review in MGNo, (Bill Only)Yes

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, slide review will always be performed at an additional charge.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Polymerase Chain Reaction (PCR)-Based Next-Generation Sequencing

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Solid Tumor Targeted Cancer Panel

Aliases Lists additional common names for a test, as an aid in searching

Oncology panel
Tumor panel
Next Gen Sequencing Test