Assisting in the diagnosis and classification of certain malignant hematological disorders
Evaluating the prognosis in patients with certain malignant hematologic disorders
Monitoring effects of treatment
Monitoring patients in remission
This test includes a charge for cell culture of fresh specimens and professional interpretation of results. Analysis charges will be incurred for total work performed, and generally include 2 banded karyograms and the analysis of 20 metaphase cells. If no metaphase cells are available for analysis, no analysis charges will be incurred. If additional analysis work is required, additional charges may be incurred.
The following algorithms are available in Special Instructions:
-Acute Promyelocytic Leukemia: Guideline to Diagnosis and Follow-up
-B-Lymphoblastic Leukemia/Lymphoma Algorithm
-Bone Marrow Staging for Known or Suspected Malignant Lymphoma Algorithm
-Laboratory Screening Tests for Suspected Multiple Myeloma
-Myelodysplastic Syndrome: Guideline to Diagnosis and Follow-up
-Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation
Cell Culture without Mitogens* followed by Chromosome Analysis
*In addition to the cell culture without mitogens, a CpG-stimulated culture will be added and 10 additional cells will be analyzed for any specimen received from a patient age 30 or older with a reason for referral of chronic lymphocytic leukemia, small lymphocytic leukemia, lymphocytosis, Waldenstrom macroglobulinemia, or when test CLLF / Chronic Lymphocytic Leukemia (CLL), FISH is ordered concurrently.
