Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: COGBL
Chromosome Analysis, Hematologic Disorders, Children’s Oncology Group Enrollment Testing, Blood
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Evaluation of pediatric blood specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children’s Oncology Group (COG) clinical trials and research protocols
Highlights
Cytogenetics testing is important for the diagnostic and prognostic classification of pediatric neoplasia and it is a critical element for enrollment of children into clinical trials affiliated with the Children’s Oncology Group (COG). For over 25 years the Mayo Clinic Genomics Laboratory has served as one of a select number of laboratories in the United States approved by the COG for the conventional chromosome analysis and FISH analysis of pediatric bone marrow, peripheral blood, and tissue specimens.
All enrollment-required elements of cytogenetics testing will be electronically submitted by the Mayo Clinic Genomics laboratory within the guidelines of COG.
Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ML20C | COG Metaphases, 1-19 | No, (Bill Only) | No |
| M25C | COG Metaphases, 20-25 | No, (Bill Only) | No |
| MG25C | COG Metaphases, >25 | No, (Bill Only) | No |
| _STAC | Ag-Nor/CBL Stain | No, (Bill Only) | No |
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
This test is only performed on specimens from pediatric patients who are candidates for enrollment in Children's Oncology Group (COG) clinical trials and research protocols.
This test includes a charge for cell culture of fresh specimens and professional interpretation of results. Analysis charges will be incurred for total work performed, and generally include 2 banded karyograms and the analysis of 20 metaphase cells. If no metaphase cells are available for analysis, no analysis charges will be incurred. If additional analysis work is required, additional charges may be incurred.
-If this test is ordered and the laboratory is informed that the patient is not on a COG protocol, this test will be canceled and automatically reordered as CHRHB / Chromosome Analysis, Hematologic Disorders, Blood.
Method Name A short description of the method used to perform the test
Cell Culture without Mitogens followed by Chromosome Analysis
NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name Lists a shorter or abbreviated version of the Published Name for a test
Aliases Lists additional common names for a test, as an aid in searching
Hematologic Chromosome Analysis
Hematologic Karyotype
Karyotype, Peripheral Blood Unstimulated
Children's Oncology Group
COG