Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Diagnosis of inherited peripheral neuropathies associated with known causal genes
Serving as a second-tier test for patients in whom previous targeted gene variant analyses for specific inherited peripheral neuropathy-related genes were negative
Identifying variants within genes known to be associated with inherited peripheral neuropathy, allowing for predictive testing of at-risk family members
This ordered service includes the option for one of several peripheral neuropathy related panel tests to be performed. The specific peripheral neuropathy panel requested must be provided in order to perform this test. Testing options include the following:
-Hereditary Motor Neuropathy Panel (23 genes)
-Hereditary Sensory Neuropathy Panel (18 genes)
-Metabolic or Syndromic Neuropathies (74 genes)
-Motor and Sensory Neuropathy Panel (82 genes)
-Peripheral Neuropathy Expanded Panel (193 genes)
-SEPT9 Gene, Full Gene Analysis (1 gene)
-Spastic Paraplegia Neuropathy Panel (41 genes)
-Custom Gene Panel (https://orders.mayocliniclabs.com/en/tools/gene_panels/)
-Custom Gene Ordering tutorial: https://vimeo.com/299737728/23d56922f1
See Frequently Asked Questions: Custom Gene Ordering Tool in Special Instructions.
See Targeted Genes and Methodology Details for Peripheral Neuropathy Gene Panels in Special Instructions for details regarding the targeted genes for each test.
*Related testing to neuromuscular conditions is available. See NMPAN / Neuromuscular Genetic Panels by Next-Generation Sequencing (NGS) for more information about neuromuscular testing.
This test may aid in the diagnosis of inherited peripheral neuropathy
Test ID | Reporting Name | Available Separately | Always Performed |
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_G103 | Peripheral Neuropathy Expanded Panel | No, (Bill Only) | No |
_G104 | Motor and Sensory Neuropathy Panel | No, (Bill Only) | No |
_G105 | Hereditary Sensory Neuropathy Panel | No, (Bill Only) | No |
_G106 | Hereditary Motor Neuropathy Panel | No, (Bill Only) | No |
_G107 | Spastic Paraplegia Neuropathy Panel | No, (Bill Only) | No |
_G108 | Metabolic or Syndromic Neuropathies | No, (Bill Only) | No |
_G132 | SEPT9 Gene, Full Gene Analysis | No, (Bill Only) | No |
G145 | Hereditary Custom Gene Panel Tier 1 | No, (Bill Only) | No |
G146 | Hereditary Custom Gene Panel Tier 2 | No, (Bill Only) | No |
G151 | Custom Gene Panel(CPT 81448) Tier 2 | No, (Bill Only) | No |
G152 | Custom Gene Panel(CPT 81448) Tier 3 | No, (Bill Only) | No |
G153 | Custom Gene Panel(CPT 81448) Tier 4 | No, (Bill Only) | No |
G154 | Custom Gene Panel(CPT 81448) Tier 5 | No, (Bill Only) | No |
This test includes the option for either one of several predefined panel tests or the option to create a custom gene panel. Pricing for the Custom Gene Panel will be based on the number of genes selected (1, 2-4, 5-14, 15-49, 50-100, and 101-500). See Custom Gene Panel Ordering in Special Instructions.
See Hereditary Peripheral Neuropathy Diagnostic Algorithm in Special Instructions.
Custom Sequence Capture and Targeted Next-Generation Sequencing (NGS)/Polymerase Chain Reaction (PCR)/qPCR, Sanger Sequencing/and/or Gene Dosage Analysis by Multiplex Ligation-Dependent Probe Amplification (MLPA)