Test ID: HCSRN    
Hepatitis C Virus (HCV) Antibody Screen with Reflex to HCV RNA by PCR, Serum

Screening for hepatitis C in primary care settings in high-risk persons with a current or past history of illicit injection drug use or a history of receiving a blood transfusion prior to 1992

Screening for hepatitis C in primary care settings in non-high risk persons born from 1945 through 1965

This test is not offered as a screening or confirmatory test for hepatitis C in blood or human cells/tissue donors.

This test profile is not useful for detection or diagnosis of acute hepatitis C virus (HCV), since HCV antibodies may not be detectable until after 2 months following exposure and HCV RNA testing is not performed on specimens with negative HCV antibody screening test results. Initial testing using HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse Transcription-PCR (RT-PCR), Serum is recommended for detection of HCV infection in such patients.

Note: In accordance with National Coverage Determination guidance, this test is indicated for asymptomatic patients born from 1945 through 1965, those with a history of injection drug use, or a history of receiving blood transfusion prior to 1992.

This screening test is indicated for testing asymptomatic individuals that may or may not have risk factors for a hepatitis C virus infection.

If the hepatitis C virus (HCV) antibody screen is reactive, then HCV RNA by reverse transcription-polymerase chain reaction (RT-PCR) will be performed at an additional charge.

See Hepatitis C: Testing Algorithm for Screening and Diagnosis in Special Instructions.

• Viral Hepatitis Serologic Profiles
• Hepatitis C: Testing Algorithm for Screening and Diagnosis

Chemiluminescence Immunoassay