BIVAL - Overview: Bivalirudin, Ecarin, Plasma
Monitoring of bivalirudin therapy for patients with prolonged baseline activated partial thromboplastin time
ETGX - Overview: Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine
Monitoring abstinence in clinical and justice system settings using ethyl glucuronide and ethyl sulfate as direct biomarkers or metabolites of ethanol This chain-of-custody test is intended to be used in a setting where the test results...
NIUCR - Overview: Nickel/Creatinine Ratio, Random, Urine
Preferred specimen type for biomonitoring nickel exposure
RIVAR - Overview: Rivaroxaban, Anti-Xa, Plasma
Measuring rivaroxaban concentration in selected clinical situations (eg, kidney insufficiency, assessment of compliance, periprocedural measurement of drug concentration, suspected overdose, advanced age, and extremes of body weight)
PIPA - Overview: Pipecolic Acid, Serum
Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in serum
CARFT - Overview: Carbamazepine, Free and Total, Serum
Monitoring carbamazepine (free and total) therapy in patients who are uremic
UPGC - Overview: Uroporphyrinogen III Synthase (Co-Synthase), Erythrocytes
Diagnosis of congenital erythropoietic porphyria This test is not useful for diagnosis of acute intermittent porphyria (AIP).
CUS1 - Overview: Copper, Serum
Diagnosis of: -Wilson disease -Primary biliary cholangitis -Primary sclerosing cholangitis
PLP - Overview: Pyridoxal 5-Phosphate, Plasma
Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes Determining the overall success of a vitamin B6 supplementation...
PRCAL - Overview: Procalcitonin, Serum
Monitoring antibiotic therapy and all-cause mortality for patients diagnosed with severe sepsis or septic shock in the Intensive Care Unit (ICU) or when obtained in the emergency department or other medical wards prior to ICU admission
Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC)...
Laboratory and Pathology Research Roundup: March 12 - Insights
known. We performed laser microdissection (LCM) of glomeruli followed by mass spectrometry (MS) in 12 cases each of DDD, C3GN, and pretransplant kidney control biopsies....
COVID-19: At-home sample collection vs. at-home testing - Insights
The concept of at-home testing for COVID-19 sounds straightforward. But there's nuance to it that's important to understand. Right now, an at-home test for COVID-19 is not available, although there may be one coming soon. But in some areas,...
Clinic Laboratory and Pathology Research Roundup: Nov. 12 - Insights
This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.
Transfusion Toons: A1 vs. A2 - Insights
Justin Kreuter, M.D., Clinical Pathologist and Medical Director of the Mayo Clinic Blood Donor Center in Rochester, Minnesota, and Theresa Malin, an Education Specialist in Transfusion Medicine at Mayo Clinic, have launched “Transfusion...