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Test Catalog
CMA - Overview: Centromere Antibodies, IgG, Serum
Evaluating patients with features of systemic autoimmune rheumatic disease, particularly systemic sclerosis, Sjogren's syndrome, or overlap disease Aiding in the phenotypic stratification of patients with systemic sclerosis (limited...
CALRC - Overview: Calreticulin ex9mut Immunostain, Technical Component Only
Identifying the presence of CALR exon 9 frameshift alterations in myeloproliferative neoplasms
CD2 - Overview: CD2 Immunostain, Technical Component Only
Determining T-cell lineage
CURCU - Overview: Copper/Creatinine Ratio, Random, Urine
Investigation of Wilson disease and obstructive liver disease using a random urine specimen
IGD - Overview: Immunoglobulin D (IgD), Serum
Providing information on the humoral immune status Identifying an IgD monoclonal gammopathy
H2MT - Overview: HER2 Amplification, Miscellaneous Tumor, FISH, Tissue
Guiding cancer therapy, as patients with HER2 amplification may be candidates for therapies that target the human epidermal growth factor receptor 2 (HER2) protein (eg, trastuzumab [Herceptin], pertuzumab) Confirming the presence of HER2...
CHLM - Overview: Chlamydia IgM, Immunofluorescence, Serum
Assessing IgM antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections
CUU - Overview: Copper, 24 Hour, Urine
Investigation of Wilson disease and obstructive liver disease using a 24-hour urine specimen
PBALP - Overview: Porphobilinogen and Aminolevulinic Acid, Plasma
An equivalent option to urine for first-line test for evaluation of a suspected acute porphyria Monitoring patients undergoing treatment for an acute intermittent porphyria or other acute porphyria
NSYPH - Overview: Syphilis IgG Enzyme Immunoassay, Serum
An aid in the diagnosis of infection with Treponema pallidum Routine prenatal screening This test is not useful for diagnosis of congenital syphilis. This test is not offered as a screening or confirmatory test for blood donor specimens.
Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (no reflex to FISH testing)
RBCS - Overview: Relative B-Cell Subset Analysis Percentage, Blood
Screening for humoral or combined immunodeficiencies, including common variable immunodeficiency, hyper IgM syndrome, among others, where B-cell subset distribution information is desired Assessing B-cell subset reconstitution after...
ESTR - Overview: Estrogen Receptor Immunostain, Technical Component Only
Qualitative detection of estrogen receptor alpha protein in a diagnostic setting
SMAS - Overview: Smooth Muscle Antibody Screen, Serum
Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes
CMSP - Overview: Inherited Congenital Myasthenic Syndrome Gene Panel, Varies
Establishing a molecular diagnosis for patients with congenital myasthenic syndrome Identifying variants within genes known to be associated with congenital myasthenic syndrome, allowing for predictive testing of at-risk family members
MBX - Overview: Muscle Pathology Consultation
Obtaining a rapid, expert opinion on muscle biopsy specimens for diagnosis of acquired or inherited muscle diseases Guiding treatment and genetic testing, as well as investigating relevance of genetic variants of unknown significance
ALAUR - Overview: Aminolevulinic Acid, Urine
Assisting in the differential diagnosis of the acute hepatic porphyrias
TTBS - Overview: Testosterone, Total and Bioavailable, Serum
Recommended second-level test for suspected increases or decreases in physiologically active testosterone: -Assessment of androgen status in cases with suspected or known sex hormone-binding globulin binding abnormalities -Assessment of...
ARBI - Overview: Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders An adjunct...
HERGM - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual
Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (with reflex to FISH testing)
DCP - Overview: Des-Gamma-Carboxy Prothrombin, Serum
Risk assessment of patients with chronic liver disease for development of hepatocellular carcinoma (HCC) Aiding in the monitoring of HCC patients post therapy if the des-gamma-carboxy prothrombin level was elevated prior to therapy
CHLAP - Overview: Chlamydia IgM and IgG Panel, Immunofluorescence, Serum
Aiding in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infection
PBGU - Overview: Porphobilinogen, Quantitative, Random, Urine
First-order test for evaluating a suspected acute porphyria: acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria
REVE2 - Overview: Erythrocytosis Evaluation, Blood
Definitive, comprehensive, and economic evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased hemoglobin or hematocrit
CHLG - Overview: Chlamydia IgG, Immunofluorescence, Serum
Assessing IgG antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections
CHIKI - Overview: Chikungunya Interpretation
Interpretation of testing that aids in the diagnosis of recent infection with Chikungunya virus in patients with recent travel to endemic areas and a compatible clinical syndrome
EXT2 - Overview: Exostosin 2 (EXT2) Immunostain, Technical Component Only
Identification of exostosin 2 associated membranous nephropathy
SEMA3 - Overview: Semaphorin 3B (SEMA3B) Immunostain, Technical Component Only
Aiding in the diagnosis of semaphorin 3B-associated membranous nephropathy
SPIRO - Overview: Spirochete Immunostain, Technical Component Only
This test will identify spirochete organisms in cases of intestinal spirochetosis, as well as cases of syphilis caused by infection with the spirochete Treponema pallidum.
CRANR - Overview: Cortisol, Free, Random, Urine
Investigating suspected hypercortisolism when a 24-hour collection is prohibitive (ie, pediatric patients)
EBVPV - Overview: Epstein-Barr Virus (EBV), Molecular Detection, PCR, Varies
Rapid qualitative detection of Epstein-Barr virus (EBV) DNA in specimens Diagnosis of disease due to EBV This test should not be used to screen asymptomatic patients.
SYPH1 - Overview: Syphilis IgG with Reflex, Enzyme Immunoassay, Serum
Aid for the diagnosis of infection with Treponema pallidum using an algorithmic approach Routine prenatal screening This test is not offered as a screening or confirmatory test for blood donor specimens. This test is not useful for...
NEPHP - Overview: Comprehensive Nephrology Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary kidney disease Establishing a diagnosis for a variety of hereditary kidney conditions including focal segmental glomerulosclerosis,...
CMVG - Overview: Cytomegalovirus (CMV) Antibodies, IgG, Serum
Determining whether a patient (especially transplant recipients and organ and blood donors) has had a recent infection or previous exposure to cytomegalovirus
TTFB - Overview: Testosterone, Total, Bioavailable, and Free, Serum
Second- or third-order test for evaluating testosterone status (eg, when abnormalities of sex hormone-binding globulin are present)
TGRP - Overview: Testosterone, Total and Free, Serum
Alternative, second-level test for suspected increases or decreases in physiologically active testosterone: -Assessment of androgen status in cases with suspected or known sex hormone-binding globulin-binding abnormalities -Assessment of...
IEICP - Overview: Inborn Errors of Immunity Comprehensive Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal history of an inborn error of immunity (IEI) Establishing a diagnosis of an IEI associated with known causal genes Identifying variants within genes known to be...
LBCS - Overview: Labile Bound Copper, Serum
May be useful in the evaluation of copper-related disorders, including Wilson disease
HCHLG - Overview: Hypercholesterolemia Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of familial hypercholesterolemia (FH), sitosterolemia, or other monogenic forms of inherited hypercholesterolemia Establishing a diagnosis of FH,...
TTRZ - Overview: TTR Gene, Full Gene Analysis, Varies
Establishing a molecular diagnosis for patients with amyloidosis Identifying variants within TTR known to be associated with amyloidosis, allowing for predictive testing of at-risk family members
Screening for common variable immunodeficiency and hyper-IgM syndromes Assessing B-cell subset reconstitution after stem cell or bone marrow transplant Assessing response to B-cell-depleting immunotherapy This test is not indicated...
EBVAB - Overview: Epstein-Barr Virus Antibody Profile, Serum
Diagnosis of Epstein-Barr virus (EBV) infectious mononucleosis or other EBV related infections Identification of prior EBV infection as part of pre-immunosuppression screening This assay is not intended for viral isolation or...
RRPRS - Overview: Rapid Plasma Reagin Screen with Reflex to Titer, Serum
Aid for the diagnosis of infection with Treponema pallidum Rapid plasma reagin testing following a positive treponemal antibody test This test is not useful as a screening or confirmatory test for blood donor specimens.
AN1TS - Overview: Antineuronal Nuclear Antibody-Type 1 (ANNA-1) Titer, Serum
Diagnosis of paraneoplastic autoimmune neuropathies, encephalomyeloradiculopathies, related neurologic disorders, and intestinal pseudo-obstruction/dysmotility associated with small-cell lung carcinoma Reporting an end titer result from...
DICET - Overview: DICER1 Mutation Analysis, Next-Generation Sequencing, Tumor
Identifying specific mutations within the DICER1 gene to assist in tumor diagnosis/classification
21OH - Overview: 21-Hydroxylase Antibodies, Serum
Investigating adrenal insufficiency Aiding in the detection of those at risk of developing autoimmune adrenal failure in the future
CMPRG - Overview: Family Member Comparator Specimen for Genome Sequencing, Varies
Submitting a biological family member's specimen to be used as a comparator for affected patients (probands) undergoing whole genome sequencing
EEST - Overview: Estradiol, Serum
All applications that require moderately sensitive measurement of estradiol: -Evaluation of hypogonadism and oligo-amenorrhea in females -Assessing ovarian status, including follicle development, for assisted reproduction protocols (eg, in...
RPRS - Overview: Rapid Plasma Reagin Screen with Reflex, Serum
Aiding in the diagnosis of recent or past Treponema pallidum infection Rapid plasma reagin screening when T pallidum antibody screen is positive This test is not useful as a screening or confirmatory test for blood donor specimens.
MNS - Overview: Manganese, Serum
Monitoring manganese exposure using serum specimens Nutritional monitoring
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Primary ciliary dyskinesia - Insights
Learn more about Mayo Clinic Laboratories’ robust approach to testing for primary ciliary dyskinesia, a rare genetic condition that can lead to chronic otosinopulmonary disease and infertility in men....
CPT Codes and LOINC Update: September 2019 - Insights
View a full list of new CPT codes, Test Classification Updates, LOINC Codes, and Z-Codes posted to mayocliniclabs.com during the month of September 2019....
https://www.mayocliniclabs.com/it-mmfiles/cpt-code-changes.xlsx
note, CPT Code changes listed on this document are effective January 1st, 2025.*** ***Updates and other changes may occur, and be reflected on this document, leading up to 2025*** ***CPT Code Updates...
MCL Primary Ciliary Dyskinesia Genetic Testing Patient Information MC1235297
MCL Primary Ciliary Dyskinesia Genetic Testing Patient Information Complete print Reset Form Primary Ciliary Dyskinesia Genetic Testing Patient Information Instructions Accurate interpretation reporting...
New communication process for CPT Code changes - Insights
Mayo Clinic Laboratories (MCL) is pleased to announce an essential update to our CPT code communication process and website layout. This change is designed to bring timely notifications for accurate billing...