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MCMLN - Overview: MayoComplete Melanoma Panel, Next-Generation Sequencing, Tumor

Determining if patients will respond to targeted therapy Assessing microsatellite instability for immunotherapy decisions

MDSDF - Overview: Myelodysplastic Syndrome (MDS), Diagnostic FISH, Varies

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myelodysplastic syndromes or other myeloid malignancies using a laboratory-designated probe set algorithm Evaluating specimens in which...

DICET - Overview: DICER1 Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the DICER1 gene to assist in tumor diagnosis/classification

AIHL - Overview: Aminoglycoside-Induced Hearing Loss, Targeted Variant Testing, Droplet Digital PCR, Varies

Identification of individuals who may be at risk for aminoglycoside-induced hearing loss (AIHL) Establishing a diagnosis of late-onset sensorineural hearing loss associated with aminoglycoside exposure Identifying mitochondrial variants...

IN16Q - Overview: CBFB::MYH11 Inversion(16), Quantitative Detection and Minimal Disease Risk Monitoring, qRT-PCR, Varies

Detection of CBFB::MYH11 gene fusion in patients recently diagnosed with acute myeloid leukemia (AML) Minimal residual disease monitoring during the clinical and therapeutic course of patients with AML

HL58R - Overview: HLA-B*5801 Genotype, Allopurinol Hypersensitivity, Varies

Identifying individuals with an increased risk of severe cutaneous adverse reactions to allopurinol based on the presence of the human leukocyte antigen HLA-B*58:01 allele

HEAB - Overview: Hepatitis B Virus e Antibody, Serum

Determining the presence or absence of detectable hepatitis B virus e antibody in monitoring infection status of individuals with chronic hepatitis B Determining infectivity of hepatitis B virus (HBV) carriers Monitoring serologic...

LALBS - Overview: Lysosomal Acid Lipase, Blood Spot

Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood spot specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.

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NELL-1 [Test in Focus] - Insights

D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...

Looking Back on Clinical Chemistry 1 - Insights

in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....

Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights

Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....

Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights

test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....

Week in Review: November 1 - Insights

Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.