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ALU - Overview: Aluminum, 24 Hour, Urine

Monitoring aluminum exposure Preferred matrix for assessment of exposure in patients with normal kidney function since rapidly filtered by kidneys Monitoring metallic prosthetic implant wear This test is not an acceptable substitute for...

AFP - Overview: Alpha-Fetoprotein (AFP) Tumor Marker, Serum

Follow-up management of patients undergoing cancer therapy, especially for testicular and ovarian tumors and for hepatocellular carcinoma Often used in conjunction with human chorionic gonadotropin.(2) This test is not recommended as a...

AN3TC - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Spinal Fluid

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from cerebrospinal fluid specimens

APMSC - Overview: Activated Partial Thromboplastin Time (APTT) Mix 1:1, Plasma

Screening for certain coagulation factor deficiencies and abnormalities (eg, factor VIII, IX, XI, or XII). Detection of coagulation inhibitors such as lupus anticoagulant, antiphospholipid antibodies, specific factor inhibitors, and...

COKEX - Overview: Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine

Detecting and confirming drug abuse involving cocaine Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by...

CUT - Overview: Copper, Liver Tissue

Diagnosing Wilson disease and primary biliary cirrhosis using liver tissue specimens

HD1 - Overview: House Dust Panel, Serum

Establishing a diagnosis of an allergy to cockroach, Dermatophagoides farinea, Dermatophagoides pteronyssinus, and house dust/H-S lab Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible...

GD65S - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Serum

Assessing susceptibility to autoimmune (type 1, insulin-dependent) diabetes mellitus and related endocrine disorders (eg, thyroiditis and pernicious anemia) Distinguishing between patients with type 1 and type 2 diabetes Confirming a...

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February 2020 - Laboratory Genetics & Genomics - Insights

A 71 yr old female with a history of a central nervous system lymphoma, an allogenic stem cell transplant and graft versus host disease was tested for...

inflammatory-bowel-disease-diagnostic-testing-algorithm.pdf

YES <50 mcg/g <50 mcg/g Abnormal >50 mcg/g Normal ANCA present ASCA IgG and IgA absent ANCA absent ASCA IgG or IgA present ANCA absent ASCA IgG or IgA absent >120 mcg/g50-120 mcg/g NO Assessing a patient...

Soft tissue - Insights

Find out how our sarcoma panel assesses gene mutations and fusions described in more than 50 types of soft tissue, bone, and other mesenchymal tumors....

July 2019 — Cardiovascular - Insights

A 50-year-old man who was known to have systemic hypertension developed sudden onset of severe back pain with associated diaphoresis. He lost...

Neuro-oncology: An integrated approach to interpreting genetic information from brain tumor samples - Insights

Mayo Clinic’s Neuro-Oncology practice, the Division of Laboratory Genetics and Genomics tests about 50 brain tumors a week, and upwards of 1,500 brain tumors a year from all over the world....