MYOGL - Overview: Myoglobin Immunostain, Technical Component Only

Marker of skeletal and cardiac muscle

NSEI - Overview: Neuron-Specific Enolase Immunostain, Technical Component Only

Characterization of neuroendocrine differentiation in tumors

NEUN - Overview: Neu-N Immunostain, Technical Component Only

Identification of neuronal nuclei

NF2F - Overview: Neurofilament (2F11) Immunostain, Technical Component Only

Aiding in the identification of neoplastic cells of neural origin or those exhibiting neuronal differentiation

NFSMI - Overview: Neurofilament (SMI31) Immunostain, Technical Component Only

Differentiating neurons (neurofilament positive) from glia (neurofilament negative)

OLIG2 - Overview: OLIG2 Immunostain, Technical Component Only

Distinguishing gliomas from neurocytomas and ependymomas

NUT - Overview: NUT Immunostain, Technical Component Only

Aiding in the diagnosis of nuclear protein in testis midline carcinoma

NKX3 - Overview: NKX3.1 Immunostain, Technical Component Only

Identifying tumors of prostatic origin

OTP - Overview: Orthopedia Homeobox Protein (OTP) Immunostain, Technical Component Only

Distinguishing lung carcinoid tumors from metastatic neuroendocrine tumors

P57I - Overview: p57 (KIP2/CDKN1C) Immunostain, Technical Component Only

Aids in the identification of cytotrophoblasts, intermediate trophoblasts, and villous stromal cells

P40 - Overview: p40 Immunostain, Technical Component Only

Diagnosis and classification of carcinomas and lymphomas

SSTR2 - Overview: Somatostatin Receptor 2 (SSTR2), Immunostain, Technical Component Only

Aids in the identification of neuroendocrine tumors

SF1 - Overview: SF-1 Immunostain, Technical Component Only

Classification of pituitary adenomas

SV40 - Overview: SV40 Immunostain, Technical Component Only

Identifying BK or JC polyomavirus

TIA1 - Overview: T-Cell Intracellular Antigen 1 (TIA-1) Immunostain, Technical Component Only

Characterizing neoplasms of cytotoxic T cells or natural killer cells

TLE1 - Overview: TLE-1 Immunostain, Technical Component Only

Aids in the identification of synovial sarcoma

TOXO - Overview: Toxoplasma Immunostain, Technical Component Only

Identification of Toxoplasma gondii infection

TCRF1 - Overview: T-Cell Receptor Beta (TCR Beta F1) Immunostain, Technical Component Only

Classification of lymphomas

THYR - Overview: Thyroglobulin Immunostain, Technical Component Only

Classification of thyroid carcinoma

VIPI - Overview: Vasoactive Intestine Polypeptide (VIP), Technical Component Only

Aiding in the identification of islet cell tumors

VZV - Overview: Varicella Zoster Virus (VZV) Immunostain, Technical Component Only

Aids in the identification of varicella zoster virus infection

TBET - Overview: T-Box Expressed in T Cells (TBET) Immunostain, Technical Component Only

Classification of lymphomas

UPII - Overview: Uroplakin II Immunostain, Technical Component Only

Characterization of urothelial carcinoma

TCL1A - Overview: T-Cell Leukemia/Lymphoma Protein 1A (TCL1A) Immunostain, Technical Component Only

Identification of T-cell leukemia and lymphoma protein overexpression in neoplasms

T46IS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence, Serum

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG in serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or encephalomyelitis

T46IC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence, Spinal Fluid

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG in cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

T46TS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence Titer, Serum

Reporting an end titer result for tripartite motif-containing protein 46 (TRIM46)-IgG in serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

T46TC - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence Titer, Spinal Fluid

Reporting an end-titer result for tripartite motif-containing protein 46 (TRIM46)-IgG in cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia,...

DRV3 - Overview: Dilute Russell's Viper Venom Time (DRVVT) Confirmation, Plasma

Confirming the presence or absence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin time clotting tests...

ESTUF - Overview: Endometrial Stromal Tumors (EST), 7p15 (JAZF1), 6p21.32 (PHF1), 17p13.3 (YWHAE) Rearrangement, FISH, Tissue

Supporting the diagnosis of endometrial stromal tumors when used in conjunction with an anatomic pathology consultation

SPBX - Overview: Epidermal Nerve Fiber Density Consultation, Varies

Investigating polyneuropathies

COGBM - Overview: Chromosome Analysis, Hematologic Disorders, Children's Oncology Group Enrollment Testing, Bone Marrow

Evaluation of pediatric bone marrow specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children's Oncology Group clinical...

LPLFX - Overview: Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia, MYD88 L265P with Reflex to CXCR4, Varies

Establishing a diagnosis of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM) Helping distinguish LPL/WM low-grade B-cell lymphoma from other subtypes Aiding in the prognosis and clinical management of lymphoplasmacytic...

NGCLN - Overview: MayoComplete Chronic Lymphoid Neoplasms, Next-Generation Sequencing, Varies

Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with chronic or low-grade B-cell lymphoid neoplasms

NGHIS - Overview: MayoComplete Histiocytic Neoplasms, Next-Generation Sequencing, Varies

Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with histiocytic neoplasms

MTBRP - Overview: Mycobacterium tuberculosis Complex, Molecular Detection, PCR, Varies

Rapid detection of Mycobacterium tuberculosis complex DNA (preferred method) Detection of M tuberculosis, when used in conjunction with mycobacterial culture This test does not assess M tuberculosis rifampin resistance. This test...

MGLE - Overview: Myasthenia Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum

Confirming the autoimmune basis of a defect in neuromuscular transmission (eg, myasthenia gravis [MG], Lambert-Eaton myasthenic syndrome [LEMS]) Distinguishing LEMS from autoimmune forms of MG Providing a quantitative autoantibody...

GAST - Overview: Gastrin, Serum

Investigation of patients with achlorhydria or pernicious anemia Investigation of patients suspected of having Zollinger-Ellison syndrome Diagnosis of gastrinoma

GCT - Overview: Galactosemia Reflex, Blood

Preferred test for diagnosis, carrier detection, and determination of genotype of galactose-1-phosphate uridyltransferase deficiency, the most common cause of galactosemia Differentiating Duarte variant galactosemia from classic...

MBX - Overview: Muscle Pathology Consultation

Obtaining a rapid, expert opinion on muscle biopsy specimens for diagnosis of acquired or inherited muscle diseases Guiding treatment and genetic testing, as well as investigating relevance of genetic variants of unknown significance

PMARG - Overview: Postmortem Arrhythmia Gene Panel, Tissue

Providing a comprehensive postmortem genetic evaluation in the setting of a sudden death suspicious for cardiac arrhythmia or with a personal or family history suggestive of a hereditary form of cardiac arrhythmia Identifying a...

PSY - Overview: Psychosine, Blood Spot

Aids in the biochemical detection of Krabbe disease and saposin A cofactor deficiency Second-tier testing or follow up testing after an abnormal newborn screening result in an infant for Krabbe disease This test is not capable of...

SCOF3 - Overview: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) and Influenza Virus Type A and Type B RNA, Molecular Detection, PCR, Varies

Simultaneous detection and differentiation of SARS-CoV-2 (cause of COVID-19), influenza A virus, and influenza B virus in upper or lower respiratory tract specimens from individuals with flu-like illnesses

TFNAB - Overview: Thyroglobulin, Tumor Marker, Fine-Needle Aspiration Biopsy Needle Wash

Confirming or excluding metastases in enlarged or ultrasonographically suspicious lymph nodes from athyrotic individuals treated for differentiated thyroid cancer in conjunction with cytologic analysis Confirming or excluding the presence...

SERU - Overview: Serotonin, 24 Hour, Urine

Diagnosis of a small subgroup of carcinoid tumors that produce predominately 5-hydroxytryptophan (5-HTP) but very little serotonin and chromogranin A Follow-up for patients with known or treated carcinoid tumors that produce predominately...

NMS1 - Overview: Necrotizing Myopathy Evaluation, Serum

Evaluating patients with suspected necrotizing autoimmune myopathy

EOSMF - Overview: Chronic Eosinophilia, Specified FISH, Varies

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (including PDGFRA, PDGFRB, FGFR1, JAK2, and ABL1) using specified...

EOSDF - Overview: Chronic Eosinophilia, Diagnostic FISH, Varies

Detecting a neoplastic clone associated with the common chromosome abnormalities seen in patients with myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement (including PDGFRA, PDGFRB, FGFR1, JAK2, and ABL1). Supporting the...

PATHC - Overview: Pathology Consultation

A subspecialty second opinion for a specific pathology question referred by a primary pathologist Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP...

WGSEQ - Overview: Gamma-Globin Full Gene Sequencing, Varies

An adjunct in the interpretation of hemoglobin electrophoresis results Evaluation for suspected gamma variants or nondeletional hereditary persistence of fetal hemoglobin Assessment of unstable gamma chain variants when other tests for...