COLIV - Overview: Collagen IV Immunostain, Technical Component Only
A marker of the basal lamina of capillaries and basement membranes in all organs
CD19I - Overview: CD19 Immunostain, Technical Component Only
Identification of normal and neoplastic B cells
CD57 - Overview: CD57 Immunostain, Technical Component Only
Marker of natural killer cells and a subset of follicular T helper cells Aiding in the identification of tumors of neuroectodermal origin
CD163 - Overview: CD163 Immunostain, Technical Component Only
Identification of cells of monocytic/histiocytic lineage, expressed late in maturation
C5FX - Overview: C5 Complement, Functional, Serum
Diagnosis of C5 deficiency Investigation of a patient with an undetectable total complement level
TICU - Overview: Titanium/Creatinine Ratio, Urine
Measurement of titanium concentration as part of a profile to assess exposure and elimination of titanium
RPTU1 - Overview: Protein/Creatinine Ratio, Random, Urine
Evaluation of renal disease Screening for monoclonal gammopathy
STLPC - Overview: St. Louis Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid
Aiding the diagnosis of St. Louis encephalitis using spinal fluid specimens
OPATM - Overview: Opiate Confirmation, Meconium
Detecting maternal prenatal opiate/opioid use up to 5 months before birth
HBELI - Overview: Hemoglobin Electrophoresis Interpretation
Interpretation for the results of hemoglobin electrophoresis Diagnosis and classification of hemoglobin disorders, including thalassemias and hemoglobin variants
PLHBB - Overview: Plasma Free Hemoglobin, Plasma
Determining whether hemolysis is occurring such as from: -Transfusion reaction -Mechanical fragmentation of red blood cells -Relative comparison to baseline levels in extracorporeal membrane oxygenation and centrifugal ventricular assist...
GNMTC - Overview: Macro/Microthrombocytopenia Gene Panel, Next-Generation Sequencing, Varies
Evaluating hereditary macro- or microthrombocytopenia disorders in patients with a personal or family history suggestive of a hereditary macro- or microthrombocytopenia disorder Diagnosing hereditary macro- or microthrombocytopenia...
GNBLF - Overview: Bleeding Disorders, Focused Gene Panel, Next-Generation Sequencing, Varies
Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder and initial laboratory testing results are suggestive for factors VII, VIII, IX, or XI deficiency, or a von Willebrand...
PMLR - Overview: PML::RARA Quantitative, PCR, Varies
Diagnosis of acute promyelocytic leukemia (APL) Detection of residual or recurrent APL Monitoring the level of PML::RARA (promyelocytic leukemia/retinoic acid receptor alpha) in APL patients
IDENT - Overview: Organism Referred for Identification, Aerobic Bacteria
Identification of pure isolates of aerobic bacteria Differentiation of members of the Staphylococcus aureus complex (S aureus, Staphylococcus argenteus, Staphylococcus schweitzeri)
PKUSC - Overview: Phenylalanine and Tyrosine, Self-Collect, Blood Spot
Monitoring effectiveness of therapy in patients with hyperphenylalaninemia in a patient-collected specimen This test is not sufficient for follow-up for abnormal newborn screening results or for establishing a diagnosis of a specific...
T3 - Overview: T3 (Triiodothyronine), Total, Serum
Second-order testing for hyperthyroidism in patients with low thyroid-stimulating hormone values and normal thyroxine levels Diagnosing triiodothyronine (T3) toxicosis This test is not useful for general screening of the population...
7AC4 - Overview: 7AC4, Bile Acid Synthesis, Serum
Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea
VWFMS - Overview: von Willebrand Factor Multimer Analysis, Plasma
Resolving discrepancies when results of complementary laboratory tests (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von Willebrand Factor Activity, Plasma; and VWAG / von Willebrand Factor Antigen, Plasma) are...
RNP - Overview: RNP Antibodies, IgG, Serum
Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...
HRTVC - Overview: Heartland Virus, RNA, Molecular Detection, PCR, Spinal Fluid
Aiding in the diagnosis of central nervous system infection caused by Heartland virus using spinal fluid specimens
ARSBW - Overview: Arylsulfatase B, Leukocytes
Supporting the biochemical diagnosis of mucopolysaccharidosis type VI (MPS VI, Maroteaux-Lamy syndrome) in whole blood specimens This test is not useful for carrier detection.
BAPS - Overview: Bile Acid Profile, Serum
Evaluating the enterohepatic cycle consisting of the biliary system, intestine, portal circulation, and hepatocytes Supporting researchers in need of free and conjugated values of all 20 bile acid species as well as total bile acid
ARBI - Overview: Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders An adjunct...
CMAFF - Overview: Chromosomal Microarray (CMA) Familial Testing, FISH
Determining the inheritance pattern of copy number changes previously identified by chromosomal microarray analysis in a patient and aiding in the clinical interpretation of the pathogenicity of the copy number change
SBULB - Overview: Spinobulbar Muscular Atrophy (Kennedy Disease), Molecular Analysis, Varies
Molecular confirmation of clinically suspected cases of sporadic or familial spinobulbar muscular atrophy (SBMA) Presymptomatic testing for individuals with a family history of SBMA and a documented expansion in the androgen receptor (AR)...
MNB - Overview: Manganese, Blood
Evaluation of central nervous system symptoms, similar to Parkinson disease, in manganese (Mn) miners and processors Characterization of liver cirrhosis Therapeutic monitoring in treatment of cirrhosis, parenteral nutrition-related Mn...
SM - Overview: Smith (Sm) Antibodies, IgG, Serum
Evaluating patients with clinical features suggestive of antinuclear antibody associated connective tissue disease and the confirmation of a diagnosis of systemic lupus erythematosus. Testing for Smith antibodies is not useful in patients...
CSTB - Overview: CSTB Gene, Repeat Expansion Analysis, Varies
Molecular confirmation of clinically suspected CSTB-related progressive myoclonic epilepsy Identifying full penetrance dodecamer repeat expansions within CSTB known to cause CSTB-related progressive myoclonic epilepsy, allowing for...
CRMTC - Overview: Collapsin Response-Mediator Protein-5 (CRMP-5) Neuronal IgG Titer, Spinal Fluid
Evaluation of neuroautoimmunity, particularly small-cell lung carcinoma and thymoma, in conjunction with other antineuronal antibodies Reporting an end titer result from cerebrospinal fluid specimens
CTXBS - Overview: Cerebrotendinous Xanthomatosis, Blood Spot
Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using dried blood spot specimens Monitoring individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the...
COWB - Overview: Cobalt, Blood
Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.
CARBI - Overview: Carbapenem Resistance Genes, Molecular Detection, PCR, Varies
Detecting and differentiating blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem intermediate or resistant results Aiding in infection control in the detection of gastrointestinal colonization of...
BPAB - Overview: Bullous Pemphigoid, BP180 and BP230, IgG Antibodies, Serum
Initial screening test in the diagnosis of bullous pemphigoid and its variants Complementing the standard serum test of indirect immunofluorescence utilizing primate esophagus substrate and primate salt-split skin substrate (CIFS /...
ANIDE - Overview: Organism Referred for Identification, Anaerobic Bacteria
Identifying anaerobic bacteria involved in human infections
ANCA - Overview: Cytoplasmic Neutrophil Antibodies, Serum
Evaluating patients with clinical features of ANCA-associated vasculitis, specifically granulomatosus with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosus with polyangiitis
FHEXA - Overview: Hexagonal Phospholipid Neutralization
Hexagonal Phospholipid Neutralization
FLACQ - Overview: Lactoferrin, Quantitative, Stool
Lactoferrin, Quantitative, Stool
PNBX - Overview: Peripheral Nerve Pathology Consultation
Evaluating diseases of the nerve and disorders that affect nerve function
TERTD - Overview: TERT Promoter Mutation Analysis, Droplet Digital PCR, Tumor
Identifying specific mutations within the TERT promoter that assist in tumor diagnosis/classification
Assessing pure isolates of Helicobacter pylori to predict clarithromycin resistance or susceptibility
Screening cadaveric or hemolyzed serum specimens for hepatitis C virus (HCV) infection in asymptomatic individuals with or without risk factors for HCV infection Note: In accordance with National Coverage Determination guidance, this test...
HCCDD - Overview: Hepatitis C Virus Antibody, Cadaveric or Hemolyzed Specimens, Symptomatic, Serum
Diagnosis of hepatitis C virus (HCV) infection in cadaveric or hemolyzed serum specimens from symptomatic patients with or without risk factors for HCV infection This test is not intended for screening blood, cell, or tissue donors. This...
FAO - Overview: Fatty Acid Oxidation Probe Assay, Fibroblast Culture
In vitro confirmation of biochemical diagnoses of the following fatty acid oxidation disorders: -Short-chain acyl-CoA dehydrogenase deficiency -Medium-chain acyl-CoA dehydrogenase deficiency -Long-chain 3-hydroxyacyl-CoA dehydrogenase...
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Diagnosis of neuromyelitis optica (NMO) Distinguishing NMOSD from multiple sclerosis early in the course of disease
NONCR - Overview: Neuro-Oncology Gene Panel, Rearrangements Only, Tumor
Identifying rearrangements that may support a diagnosis or help determine prognosis for patients with central nervous system tumors Identifying rearrangements within genes known to be associated with response or resistance to specific...
UNIPD - Overview: Uniparental Disomy, Varies
Evaluation of patients presenting with mosaicism, confined placental mosaicism, or Robertsonian translocations Evaluation of patients presenting with features of disorders known to be associated with uniparental disomy (eg, Russell-Silver...
SZDIA - Overview: Sezary Diagnostic Flow Cytometry, Blood
Identifying immunophenotypically aberrant T-cell populations with restricted expression of T-cell receptor beta-chain constant in peripheral blood, to roughly assess the circulating tumor burden in cutaneous T-cell lymphomas
PNTO - Overview: Streptococcus pneumoniae IgG Antibodies, Total, Serum
Assessing the IgG antibody response to active immunization with nonconjugated 23-valent pneumococcal vaccines Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal...
FALBU - Overview: Albuterol, Serum/Plasma
Albuterol, Serum/Plasma
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....