GBM - Overview: Glomerular Basement Membrane Antibodies, IgG, Serum

Evaluating patients with clinical features of anti-glomerular basement disease, including rapidly progressive glomerulonephritis or pulmonary hemorrhage

MONOF - Overview: Monocyte Repartition by CD14/CD16, Blood

Aiding in the diagnosis and monitoring of chronic myelomonocytic leukemia

MUSK - Overview: Muscle-Specific Kinase (MuSK) Autoantibody, Serum

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative Establishing a quantitative baseline value...

GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum

Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma

RBR - Overview: Retinol-Binding Protein, Random, Urine

Assessing renal tubular injury or dysfunction using random urine collections Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction.(2)

SORD - Overview: Sorbitol and Xylitol, Quantitative, Random, Urine

Screening for sorbitol dehydrogenase deficiency-related neuropathy

TACPK - Overview: Tacrolimus, Peak, Blood

Assessment of postdosing (peak) blood tacrolimus concentrations

SIIRO - Overview: Sirolimus, Whole Blood

Monitoring whole blood sirolimus concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...

T3FR - Overview: T3 (Triiodothyronine), Free, Serum

A second- or third-level test of thyroid function Confirmation of hyperthyroidism, supplementing the T4 (tetraiodothyronine), sensitive thyrotropin, and total T3 assays Evaluating clinically euthyroid patients who have an altered...

GASTN - Overview: Gastrin Immunostain, Technical Component Only

Characterization of islet cell tumors and endocrine tumors of the gastrointestinal tract

HEG1 - Overview: HEG1 Immunostain, Technical Component Only

Diagnosis of epithelioid mesothelioma versus non-small cell carcinoma

SOMAT - Overview: Somatostatin Immunostain, Technical Component Only

Aids in the characterization of pancreatic islet cell tumors or other neuroendocrine tumors

CDKP1 - Overview: CD68 (KP1) Immunostain, Tissue, Technical Component Only

Aiding in the identification of histocytic and myeloid lineage cells

LFABP - Overview: Liver Fatty Acid-Binding Protein (L-FABP) Immunostain, Technical Component Only

Classification of hepatic adenomas

FASC - Overview: Fascin Immunostain, Technical Component Only

Classification of lymphomas

P63 - Overview: p63 Immunostain, Technical Component Only

Aiding in identifying squamous, urothelial, or myoepithelial differentiation in tumors

TCL1A - Overview: T-Cell Leukemia/Lymphoma Protein 1A (TCL1A) Immunostain, Technical Component Only

Identification of T-cell leukemia and lymphoma protein overexpression in neoplasms

MCTGC - Overview: Chlamydia trachomatis and Neisseria gonorrhoeae, Miscellaneous Sites, Nucleic Acid Amplification, Varies

Detecting Chlamydia trachomatis and Neisseria gonorrhoeae in non-US Food and Drug Administration-approved specimen types This test is not intended for use in medico-legal applications. This test is not useful for the detection of...

CMAMT - Overview: Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue

Diagnosis of congenital copy number changes in products of conception, including aneuploidy (ie, trisomy or monosomy) and structural abnormalities Diagnosing chromosomal causes for fetal death Determining recurrence risk of future...

EHBAP - Overview: Ehrlichia/Babesia Antibody Panel, Immunofluorescence, Serum

As an adjunct in the diagnosis of infection with Anaplasma phagocytophilum, Ehrlichia chaffeensis, or Babesia microti Seroepidemiological surveys of the prevalence of the infection in certain populations

PD2T - Overview: Pompe Disease Second-Tier Newborn Screening, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for Pompe disease (decreased acid alpha-glucosidase enzyme activity) Follow-up testing for evaluation of an abnormal newborn screening result for Pompe disease

GNHTC - Overview: Hereditary Thrombocytopenia Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary thrombocytopenia disorders in patients with a personal or family history suggestive of a hereditary thrombocytopenia disorder Diagnosing hereditary thrombocytopenia disorders for patients in whom phenotypic testing is...

ASHA - Overview: Arsenic, Hair

Detection of nonacute arsenic exposure in hair specimens

ALS - Overview: Aldolase, Serum

Detection of muscle disease

LITH - Overview: Lithium, Serum

Monitoring therapy of patients with bipolar disorders, including recurrent episodes of mania and depression Evaluating lithium toxicity

JCV - Overview: JC Virus Detection by In Situ Hybridization

Confirming a clinical and histopathologic diagnosis of progressive multifocal leukoencephalopathy

TMP - Overview: Trimethoprim, Serum

Monitoring trimethoprim therapy to ensure drug absorption, clearance, or compliance

CMACB - Overview: Chromosomal Microarray, Congenital, Blood

First-tier, postnatal testing for individuals with multiple anomalies that are not specific to well-delineated genetic syndromes, apparently nonsyndromic developmental delay or intellectual disability, or autism spectrum disorders as...

CMPRE - Overview: Family Member Comparator Specimen for Exome Sequencing, Varies

Submitting a biological family member's specimen to be used as a comparator for affected patients (probands) undergoing whole exome sequencing

BAP1Z - Overview: BAP1-Tumor Predisposition Syndrome, BAP1 Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of BAP1-tumor predisposition syndrome (BAP1-TPDS) Establishing a diagnosis of BAP1-TPDS allowing for targeted cancer surveillance based on associated risks Identifying...

HBABY - Overview: Hepatitis B Virus Perinatal Exposure Follow-up Panel, Serum

Determining hepatitis B virus infection and immunity status (with or without perinatal prophylaxis) in infants born to mothers with chronic hepatitis B

QFT4 - Overview: QuantiFERON-TB Gold Plus, Blood

Indirect test for Mycobacterium tuberculosis infection, to be used in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations This test is not recommended for use for diagnosis of active tuberculosis...

STK1Z - Overview: Peutz-Jeghers Syndrome, STK11, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of Peutz-Jeghers syndrome (PJS) Establishing a diagnosis of PJS allowing for targeted cancer surveillance based on associated risks Identifying variants within genes known...

C2AD2 - Overview: PrecivityAD2, Plasma

Assisting in the evaluation of adult patients, aged 55 years and older, with signs or symptoms of mild cognitive impairment or dementia who are being assessed for Alzheimer disease and other causes of cognitive decline This is not...

TICKS - Overview: Tick-Borne Disease Antibodies Panel, Serum

Evaluation of the most common tick-borne diseases found in the United States, including Lyme disease, human monocytic and granulocytic ehrlichiosis, and babesiosis Evaluation of patients with a history of, or suspected, tick exposure who...

CD40 - Overview: B-Cell CD40 Expression by Flow Cytometry, Blood

Evaluating patients for hyper-IgM type 3 (HIGM3) syndrome due to defects in CD40, typically seen in patients less than 10 years Assessing B-cell immune competence in other clinical contexts, including autoimmunity, malignancy, and...

BTDZ - Overview: Biotinidase Deficiency, BTD Full Gene Analysis, Varies

Second-tier test for confirming biotinidase deficiency (indicated by biochemical testing or newborn screening) Carrier testing of individuals with a family history of biotinidase deficiency, but disease-causing mutations have not been...

CEE52 - Overview: CD52 Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD52 Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

HCMM - Overview: Homocysteine (Total), Methylmalonic Acid, and Methylcitric Acid, Blood Spot

Second-tier assay of newborn screening specimens when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screen

I2SWB - Overview: Iduronate-2-Sulfatase, Leukocytes

Supporting the biochemical diagnosis of mucopolysaccharidosis II (MPS II; Hunter syndrome) in whole blood specimens This test is not useful for carrier detection for MPS II.

GMCSF - Overview: Granulocyte Monocyte-Colony Stimulating Factor, Plasma

Measuring the concentration of granulocyte macrophage-colony stimulating factor (GM-CSF) in plasma Understanding the etiology of chronic inflammatory diseases or infections, when used in conjunction with clinical information and other...

LGB3S - Overview: Globotriaosylsphingosine, Serum

Diagnosis and monitoring of Fabry disease

MGRNA - Overview: Neisseria gonorrhoeae, Miscellaneous Sites, Nucleic Acid Amplification, Varies

Detecting Neisseria gonorrhoeae in non-US Food and Drug Administration-approved specimen types This test is not intended for use in medico-legal applications.

PKU - Overview: Phenylalanine and Tyrosine, Plasma

Monitoring effectiveness of dietary therapy in patients with hyperphenylalaninemia

TSTIM - Overview: Targeted Stimulant Screen, Random, Urine

Aiding in the determination of compliance or identify illicit stimulant drug use This test is not intended for use in employment-related testing.

TSPU - Overview: Targeted Stimulant Screen, Random, Urine

Determining compliance or identifying illicit stimulant drug use This test is not intended for employment-related testing.

SALMC - Overview: Salmonella Culture, Feces

Determining whether Salmonella species may be the cause of diarrhea Reflexive testing for Salmonella species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than 3...

HERGM - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual

Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (with reflex to FISH testing)

APGP - Overview: Acute Porphyria Gene Panel, Varies

Establishing a molecular diagnosis for patients with acute porphyria Identifying variants within genes known to be associated with acute porphyria, allowing for predictive testing of at-risk family members

DHRP - Overview: Dihydrorhodamine Flow Cytometric Phorbol Myristate Acetate Test, Blood

Evaluating chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase deficiency Monitoring chimerism and nicotinamide adenine dinucleotide phosphate oxidase (NOX) function post-hematopoietic cell...