HMDB - Overview: Heavy Metals Screen with Demographics, Blood

Detecting exposure to arsenic, lead, cadmium, and mercury

AHEP - Overview: Acute Viral Hepatitis Profile, Serum

Differential diagnosis of recent acute viral hepatitis

MPSQU - Overview: Mucopolysaccharides Quantitative, Random, Urine

Supporting the biochemical diagnosis of one of the mucopolysaccharidoses: types I, II, III, IV, VI, or VII

MPS2B - Overview: Endogenous Mucopolysaccharidosis Type II (I2S [Iduronate-2-Sulfatase]) Biomarker, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type II (MPS II, decreased iduronate-2-sulfatase) Follow-up testing for evaluation of an abnormal newborn screening result for MPS II This...

TBPZA - Overview: Susceptibility, Mycobacterium tuberculosis Complex, Pyrazinamide, Varies

Susceptibility testing of Mycobacterium tuberculosis complex isolates growing in pure culture against pyrazinamide This test is not useful for Mycobacterium bovis and Myocobacterium bovis bacille Calmette-Guerin (BCG) isolates as they are...

CDCU - Overview: Cadmium/Creatinine Ratio, Urine

Detecting exposure to cadmium using random urine specimens

NICOS - Overview: Nicotine and Metabolites, Serum

Monitoring tobacco use in a clinical setting

CDOU - Overview: Cadmium Occupational Exposure, Random, Urine

Detecting occupational exposure to cadmium using random urine specimens

WNVS - Overview: West Nile Virus, RNA, PCR, Molecular Detection, Serum

Rapid testing for West Nile virus (WNV) RNA (lineage 1 and lineage 2) using serum specimens An adjunctive test to serology for detection of early WNV infection (ie, first few days after symptom onset) This test should not be used for...

HGH - Overview: Growth Hormone, Serum

Diagnosis of acromegaly and assessment of treatment efficacy when interpreted in conjunction with results from glucose suppression test Diagnosis of human growth hormone deficiency when interpreted in conjunction with results from growth...

BAIPD - Overview: Bile Acids for Peroxisomal Disorders, Serum

Biomarker for peroxisomal biogenesis disorders, such as Zellweger spectrum disorder and single enzyme defects of bile acid synthesis, including D-bifunctional protein deficiency and alpha methyl CoA racemases Monitoring patients receiving...

MPS2R - Overview: Endogenous Mucopolysaccharidosis Type II (I2S [Iduronate-2-Sulfatase]) Biomarker Reflex, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type II (MPS II, decreased iduronate-2-sulfatase) where quantitation of the glycosaminoglycans dermatan and heparan sulfate is desired in...

BRGYP - Overview: Hereditary Breast/Gynecologic Cancer Panel, Varies

Evaluating patients with a personal or family history suggestive of a hereditary breast or gynecological cancer syndrome Establishing a diagnosis of a hereditary breast or gynecological cancer syndrome allowing for targeted cancer...

SFIGS - Overview: IgG, Serum

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions as a part of a profile

AACYL - Overview: Aminoacylase-1 Deficiency, Urine

Follow-up quantitation of abnormal organic acid elevations of N-acetylated amino acids, in particular N-acetylalanine, N-acetylglycine, N-acetylmethionine, and N-acetylglutamic acid Diagnosis of individuals with aminoacylase-1...

NCSRY - Overview: Nicotine Survey, Serum

Monitoring tobacco use in a health fair setting

PRMB - Overview: Primidone and Phenobarbital, Serum

Assessing compliance Monitoring for appropriate therapeutic levels of primidone and phenobarbital Assessing toxicity

CDU - Overview: Cadmium, 24 Hour, Urine

Detecting exposure to cadmium, a toxic heavy metal, in 24-hour urine specimens

HCHLG - Overview: Hypercholesterolemia Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of familial hypercholesterolemia (FH), sitosterolemia, or other monogenic forms of inherited hypercholesterolemia Establishing a diagnosis of FH,...

MPS1Z - Overview: Hurler Syndrome, Full Gene Analysis, Varies

Identifying variants within the IDUA gene Confirmation of a diagnosis of mucopolysaccharidosis type I (MPS-I) Carrier testing when there is a family history of MPS- I, but disease-causing variants have not been previously identified

PSY - Overview: Psychosine, Blood Spot

Aids in the biochemical detection of Krabbe disease and saposin A cofactor deficiency Second-tier testing or follow up testing after an abnormal newborn screening result in an infant for Krabbe disease This test is not capable of...

SHPV - Overview: Human Papillomavirus (HPV) DNA Detection with Genotyping, High-Risk Types by PCR, SurePath, Varies

Detection of high-risk (HR) genotypes associated with the development of cervical cancer An aid in triaging women with abnormal Pap smear test results Individual genotyping of human papillomavirus (HPV)-16 and/or HPV-18, if present...

LDALD - Overview: Lysosomal and Peroxisomal Disorders Newborn Screen, Blood Spot

First-tier newborn screen for the lysosomal disorders: Fabry, Gaucher, Krabbe, mucopolysaccharidosis I (MPS I) and II (MPS II), infantile neurovisceral or chronic visceral acid sphingomyelinase deficiency, and Pompe (glycogen storage...

CHLBF - Overview: Cholesterol, Body Fluid

Aiding in the diagnosis of a cholesterol effusion or cholesterol-rich pseudochylous effusion in body fluids Distinguishing between chylous and pseudochylous pleural effusions Distinguishing between malignant and nonmalignant ascites

DRPL - Overview: Dentatorubral-Pallidoluysian Atrophy (DRPLA) Gene Analysis, Varies

Confirming the diagnosis of dentatorubral-pallidoluysian atrophy (DRPLA) for symptomatic patients Predictive testing for individuals with a family history of DRPLA and a documented expansion in the ATN1 gene in an affected family member

MPSWB - Overview: Mucopolysaccharidosis, Blood

Supporting the biochemical diagnosis of mucopolysaccharidoses type I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in whole blood specimens

META3 - Overview: Metanephrines with 3-Methoxytyramine, 24 Hour, Urine

A first- and second-tier screening test for the presumptive diagnosis of catecholamine-secreting pheochromocytomas and paragangliomas

SESPF - Overview: Sesame Seed, IgE, with Reflex to Sesame Seed Component, IgE, Serum

Evaluating patients with suspected sesame seed allergy

T3 - Overview: T3 (Triiodothyronine), Total, Serum

Second-order testing for hyperthyroidism in patients with low thyroid-stimulating hormone values and normal thyroxine levels Diagnosing triiodothyronine (T3) toxicosis This test is not useful for general screening of the population...

WNVUR - Overview: West Nile Virus, RNA, PCR, Molecular Detection, Random, Urine

Rapid testing for West Nile virus (WNV) RNA (lineage 1 and lineage 2) An adjunctive test to serology for detection of early WNV infection (ie, first few days after symptom onset), with urine specimens potentially retaining WNV RNA longer...

TSTIM - Overview: Targeted Stimulant Screen, Random, Urine

Aiding in the determination of compliance or identify illicit stimulant drug use This test is not intended for use in employment-related testing.

TSPU - Overview: Targeted Stimulant Screen, Random, Urine

Determining compliance or identifying illicit stimulant drug use This test is not intended for employment-related testing.

HRTVC - Overview: Heartland Virus, RNA, Molecular Detection, PCR, Spinal Fluid

Aiding in the diagnosis of central nervous system infection caused by Heartland virus using spinal fluid specimens

MMGEN - Overview: Mycoplasma genitalium, Transcription-Mediated Amplification, Post-Prostatic Massage Fluid/Urine or Peritoneal Fluids

Detecting Mycoplasma genitalium in cases of suspected infection in peritoneal fluid or prostatic secretion (VBIII) fluid/urine This test is not intended for use in medico-legal applications.

WAGDR - Overview: Alpha Globin Cluster Locus Deletion/Duplication, Blood

Diagnosis of alpha-thalassemia Carrier screening for individuals from high-risk populations for alpha-thalassemia This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.

ADVQU - Overview: Adenovirus DNA Detection and Quantification, Plasma

Aiding in the diagnosis of disseminated adenovirus infections in at-risk individuals Measuring adenoviral load in plasma to monitor disease progression and antiviral response in individuals with disseminated infection

SFIG - Overview: Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions

PREGN - Overview: Pregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency

RAVU - Overview: Ravulizumab, Serum

Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...

HCVG - Overview: Hepatitis C Virus Genotype, Serum

Determining hepatitis C virus (HCV) genotype (1 to 5) to guide antiviral therapy in patients with chronic hepatitis C Differentiating between HCV subtypes 1a and 1b This assay should not be used as a screening test for HCV infection. It...

APOL1 - Overview: APOL1 Genotype, Varies

Determining an individual's APOL1 genotype This test is not useful for clinical management of individuals with APOL1 risk genotypes. This test alone is not useful for determining eligibility for donation or receipt of kidney...

MPSBS - Overview: Mucopolysaccharidosis, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in dried blood spot specimens

CORTC - Overview: Corticosterone, Serum

Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of 11-beta-hydroxylase 1 (CYP11B1) versus 11-beta-hydroxylase 2 (CYP11B2) deficiency, and the diagnosis of glucocorticoid-responsive hyperaldosteronism...

ADALX - Overview: Adalimumab Quantitative with Reflex to Antibody, Serum

Therapeutic drug monitoring of adalimumab concentration and antibody levels, if appropriate

CSFP - Overview: Carrier Screen, Focused Panel, Varies

Expanded carrier screening for reproductive risk assessment purposes This test is not useful for clinical diagnosis of an affected individual.

PAI1 - Overview: Plasminogen Activator Inhibitor Antigen, Plasma

Identification of heredity elevation or deficiency of plasminogen activator inhibitor type 1 Determination of risk for veno-occlusive disease associated with bone marrow transplantation Differential diagnosis of impaired fibrinolysis...

TOSU - Overview: Targeted Opioid Screen, Random, Urine

Determining compliance or identifying illicit opioid drug use using urine specimens This test is not intended for employment-related testing.

CDGN - Overview: Congenital Disorders of N-Glycosylation, Serum

Screening for N-linked congenital disorders of glycosylation Providing information on specific structural oligosaccharide abnormalities to potentially direct further genetic testing

ASU24 - Overview: Arsenic with Reflex, 24 Hour, Urine

Preferred screening test for detection of arsenic exposure using 24-hour urine specimens

TOPSU - Overview: Targeted Opioid Screen, Random, Urine

Qualitatively (present vs not detected) identifying 33 opioid compounds (parent drug and metabolites) in urine to help determine compliance or identify illicit opioid drug use This test is not intended for use in employment-related...