POWV - Overview: Powassan Virus, IgM, Enzyme-Linked Immunosorbent Assay, Serum

Diagnosis of Powassan virus infection. This test should not be used as a screening procedure for the general population. This test should not be used as a "test of cure."

SEAS - Overview: Seasonal Inhalants Allergen Profile, Serum

Establishing a diagnosis of an allergy to seasonal inhalants Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...

THIO - Overview: Thiopurine Metabolites, Whole Blood

Aids physicians in dose adjustments, minimizing dose-dependent toxicity, and monitoring compliance of thiopurine drug therapy

TPO - Overview: Thyroperoxidase Antibodies, Serum

Aiding in the diagnosis of thyroid autoimmune disorders Differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism As a diagnostic tool in deciding whether to treat a patient who has subclinical...

URBRP - Overview: Ureaplasma species, Molecular Detection, PCR, Blood

Rapid, sensitive, and specific identification of Ureaplasma urealyticum and Ureaplasma parvum from whole blood This test is not intended for medicolegal use.

INI1 - Overview: Integrase Interactor 1 (INI1/BAF47) Immunostain, Technical Component Only

Part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms

HG34W - Overview: Histone 3.3 G34W (H3F3A G34W) Immunostain, Technical Component Only

Aiding in the diagnosis of giant cell tumor of bone

SOX11 - Overview: SOX11 Immunostain, Technical Component Only

Identification of mantle cell lymphomas

TRAP - Overview: Tartrate-Resistant Acid Phosphatase (TRAP) Immunostain, Technical Component Only

Classification of leukemias and lymphomas

TTFK5 - Overview: Thyroid Transcription Factor 1 (TTF1) (SPT24) and Keratin 5 (KRT5) Immunostain, Technical Component Only

Thyroid transcription factor 1aids in the classification of carcinomas of unknown origin Keratin 5 aids in the identification of squamous cell carcinoma

APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only

Aids in the identification of amyloid precursor protein present in Alzheimer disease

BAP1 - Overview: BAP1 Immunostain, Technical Component Only

As part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms

CTSK - Overview: Cathepsin K Immunostain, Technical Component Only

Evaluation for perivascular epithelioid cell neoplasms (PEComas), alveolar soft part sarcoma, and translocation-associated renal cell carcinomas

WNMC - Overview: West Nile Virus Antibody, IgM, Spinal Fluid

Aids in diagnosing central nervous system West Nile virus infections during the acute phase

WNGC - Overview: West Nile Virus Antibody, IgG, Spinal Fluid

Aids in diagnosing recent or past central nervous system West Nile virus infection

LMO2 - Overview: LIM Domain Only 2 (LMO2) Immunostain, Technical Component Only

Classification of lymphomas

KIMEL - Overview: Ki67 + Melan A Immunostain, Technical Component Only

Ki67 is a marker of proliferation in neoplasms Melan A aids in the identification of melanoma

PAX8 - Overview: PAX8 Immunostain, Technical Component Only

Aids in the identification of renal cell carcinomas, as well as papillary thyroid carcinomas and tumors of Mullerian origin

P40NA - Overview: p40 + Napsin A Immunostain, Technical Component Only

p40 aids in the classification of carcinomas and lymphomas Napsin A aids in the identification of primary lung adenocarcinoma

P16 - Overview: p16 (INK4a/CDKN2A) Immunostain, Technical Component Only

Aids in the identification of human papilloma virus infection

DIS - Overview: Human Leukocyte Antigens (HLA) Class I and II Disease Association Typing, Low Resolution, Blood

Identifying class I and II human leukocyte antigens (HLA) for potential disease associations or markers for drug hypersensitivity

BAKDM - Overview: BCR/ABL1, Tyrosine Kinase Inhibitor Resistance, Kinase Domain Mutation Screen, Sanger Sequencing, Varies

Evaluating patients with chronic myelogenous leukemia and Philadelphia chromosome positive B-cell acute lymphoblastic leukemia receiving tyrosine kinase inhibitor (TKI) therapy, who are apparently failing treatment Preferred initial test...

CTP10 - Overview: Catecholamine Fractionation, Standing, Plasma, Free

Diagnosis of pheochromocytoma and paraganglioma in specimens collected from individuals in a standing position, as an auxiliary test to fractionated plasma and urine metanephrine measurements Diagnosis and follow-up of patients with...

CHRCV - Overview: Chromosome Analysis, Chorionic Villus Sampling

Prenatal diagnosis of chromosome abnormalities, including aneuploidy (ie, trisomy or monosomy) and balanced rearrangements This test is not appropriate as a first-tier test for detecting gains or losses of chromosomal material in...

HISGT - Overview: Histone Genes Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the H3-3A, H3-3B, H3C2, H3C3 and H3C14 genes that assist in tumor diagnosis/classification

PBDV - Overview: Lead, Venous, with Demographics, Blood

Detecting lead toxicity in venous blood specimens

LNBAI - Overview: Lyme Central Nervous System Infection IgG, Antibody Index, Spinal Fluid

Providing antibody index information to aid in the diagnosis of neuroinvasive Lyme disease or neuroborreliosis due to Borrelia species associated with Lyme disease (eg, Borrelia burgdorferi, Borrelia garinii, Borrelia afzelli)

IDHT - Overview: IDH1 and IDH2 Mutation Analyses, Next-Generation Sequencing, Tumor

Identifying specific mutations within the IDH1 and IDH2 genes that assist in tumor diagnosis/classification and predict response to targeted therapy

MCGST - Overview: MayoComplete Gastrointestinal Stromal Tumor (GIST) Panel, Next-Generation Sequencing, Tumor

Establishing diagnosis and identifying targeted therapies for patients with gastrointestinal stromal tumors Assessing microsatellite instability

LMALP - Overview: Malaria PCR with Parasitemia Reflex, Varies

Detection of Plasmodium DNA and identification of the infecting species, with reflex percent parasitemia calculated using thin blood films for positive cases An adjunct to conventional microscopy of Giemsa-stained films Detection and...

PBPFD - Overview: Lead Profile Occupational Exposure, Blood

Detecting lead toxicity due to occupational exposure

MYEFL - Overview: Myelodysplastic Syndrome by Flow Cytometry, Bone Marrow

Detecting increased blasts Characterizing blast phenotypes Identifying abnormal patterns of myeloid maturation as seen in myelodysplastic syndromes and other clonal myeloid neoplasms Providing additional adjunct diagnostic information in...

HPFLU - Overview: Influenza Virus Type A and Type B and Respiratory Syncytial Virus (RSV) RNA, Molecular Detection, PCR, Varies

Simultaneous detection of influenza A virus, influenza B virus, and respiratory syncytial virus in upper or lower respiratory tract specimens from individuals with flu-like illnesses

ACASM - Overview: Pernicious Anemia Cascade, Serum

Diagnosis of pernicious anemia Diagnosis of vitamin B12 deficiency-associated neuropathy

PEWE - Overview: Porphyrins Evaluation, Washed Erythrocytes

Preferred test for analysis of erythrocyte porphyrins Establishing a biochemical diagnosis of erythropoietic protoporphyria, and X-linked dominant protoporphyria

SDHMP - Overview: SDH Genes Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the SDHA, SDHB, SDHC, and SDHD genes to assist in tumor diagnosis/classification, including pheochromocytoma/paraganglioma, renal cell carcinoma, and pituitary adenoma

TAB - Overview: Thyroid Autoantibodies Profile, Serum

As an adjunct in the diagnosis of autoimmune thyroid diseases: Hashimoto disease, postpartum thyroiditis, neonatal hypothyroidism, and Graves disease Differentiating thyroid autoimmune disorders from nonautoimmune goiter or...

RPCWT - Overview: Renal Pathology Consultation, Wet Tissue

Evaluating and managing patients with kidney disease Following the progression of known kidney disease or response to therapy Determining the cause of dysfunction in the transplanted kidney (allograft)

25HDN - Overview: 25-Hydroxyvitamin D2 and D3, Serum

Diagnosis of vitamin D deficiency Differential diagnosis of causes of rickets and osteomalacia Monitoring vitamin D replacement therapy Diagnosis of hypervitaminosis D

GNANT - Overview: Antithrombin Deficiency, SERPINC1 Gene, Next-Generation Sequencing, Varies

Evaluating antithrombin AT deficiency in patients with a personal or family history suggestive of this hereditary thrombophilia Confirming an AT deficiency diagnosis with the identification of a known or suspected disease-causing...

CGAK - Overview: Chromogranin A, Serum

Aiding in monitoring disease progression during the course of disease and treatment in patients with gastroenteropancreatic neuroendocrine tumors (grade 1 and grade 2) when used in conjunction with other clinical methods This test is not...

ATAXP - Overview: Inherited Ataxia Gene Panel, Varies

Establishing a molecular diagnosis for patients with ataxia Identifying variants within genes known to be associated with ataxia, allowing for predictive testing of at-risk family members

HIESG - Overview: Hyper-IgE Syndrome Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of hyper-IgE syndrome (HIES) Establishing a diagnosis of HIES, allowing for appropriate management and surveillance for disease features...

RABMP - Overview: Inherited Rhabdomyolysis and Metabolic Myopathy Panel, Varies

Establishing a molecular diagnosis for patients with rhabdomyolysis and metabolic myopathy Identifying variants within genes known to be associated with rhabdomyolysis and metabolic myopathy, allowing for predictive testing of at-risk...

MPAGP - Overview: Methylmalonic Aciduria-Propionic Aciduria Combined Gene Panel, Varies

Follow up for abnormal biochemical results suggestive of methylmalonic acidemia or propionic acidemia Establishing a molecular diagnosis for patients with methylmalonic acidemia or propionic acidemia Identifying variants within genes...

TSCP - Overview: Tuberous Sclerosis Gene Panel, Varies

Establishing a molecular diagnosis in individuals with features of tuberous sclerosis complex (TSC). Identifying pathogenic variants within the TSC1 and TSC2 genes known to be associated with TSC, allowing for predictive testing of at-risk...

TIKLB - Overview: Tick-Borne Panel, Molecular Detection, PCR, Blood

Evaluating patients with suspected human monocytic ehrlichiosis, human granulocytic anaplasmosis, babesiosis, or Borrelia miyamotoi infection Evaluating patients with a history of, or suspected, tick exposure who are presenting with...

VIRID - Overview: Viral Susceptibility, Defects in Intrinsic and Innate Immunity, Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity causing a hereditary form of severe viral susceptibility Establishing a diagnosis of hereditary form of...

NHHA - Overview: Hereditary Hemolytic Anemia Gene Panel, Next-Generation Sequencing, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of hereditary hemolytic anemias, including red blood cell (RBC) membrane/hydration disorders, RBC enzymopathies, and congenital...

CSFME - Overview: Meningitis/Encephalitis Pathogen Panel, PCR, Spinal Fluid

Rapid detection of meningitis and encephalitis caused by: -Escherichia coli K1 (K1 serotype only) -Haemophilus influenzae -Listeria monocytogenes -Neisseria meningitidis (encapsulated strains only) -Streptococcus agalactiae (Group B...