ALBS1 - Overview: Albumin, Serum
Assessing nutritional status Aiding in the diagnosis of multiple sclerosis when used in conjunction with serum IgG, and cerebrospinal fluid IgG and albumin concentrations
NH3V - Overview: Ammonia, Plasma
Assisting in the diagnosis of hepatic coma Investigating and monitoring treatment for inborn errors of metabolism Evaluating patients with advanced liver disease
AST - Overview: Aspartate Aminotransferase (AST) (GOT), Serum
Diagnosing and monitoring liver disease, particularly diseases resulting in a destruction of hepatocytes
OSMOF - Overview: Osmolality, Feces
Measurement of osmolality for the workup of cases of chronic diarrhea Diagnosis of factitious diarrhea (where patient adds fluid to stool to simulate diarrhea)
HLHGP - Overview: Primary Hemophagocytic Lymphohistiocytosis Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of familial hemophagocytic lymphohistiocytosis (F-HLH) Establishing a diagnosis of F-HLH, allowing for appropriate management and...
KETGP - Overview: Ketone Disorders Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a ketone disorder Establishing a molecular diagnosis for patients with ketone disorders Identifying variants within genes known to be associated with ketone disorders, allowing for...
MMAGP - Overview: Methylmalonic Aciduria Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a methylmalonic acidemia Establishing a molecular diagnosis for patients with methylmalonic acidemia Identifying variants within genes known to be associated with methylmalonic...
IMSNP - Overview: Inherited Motor and Sensory Neuropathy Gene Panel, Varies
Establishing a molecular diagnosis for patients with hereditary motor and sensory neuropathy (HMSN) or Charcot-Marie-Tooth (CMT) disease Identifying variants within genes known to be associated with HMSN or CMT disease, allowing for...
GNF13 - Overview: Factor XIII Deficiency, F13A1 and F13B Genes, Next-Generation Sequencing, Varies
Evaluating factor XIII deficiency (FXIIID) in patients with a personal or family history suggestive of FXIIID Confirming an FXIIID diagnosis with the identification of known or suspected disease-causing alterations in the F13A1 or F13B...
NSRGG - Overview: Noonan Syndrome and Related Conditions Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of Noonan syndrome, Noonan syndrome with multiple lentigines, Noonan syndrome with loose anagen hair, cardiofaciocutaneous syndrome, Costello syndrome,...
Establishing a molecular diagnosis for patients with frontotemporal dementia (FTD) and/or amyotrophic lateral sclerosis (ALS) Identifying variants within genes known to be associated with FTD and/or ALS, allowing for predictive testing of...
PSGN - Overview: Plasminogen Activity, Plasma
Evaluating patients with ligneous conjunctivitis (strong association with homozygous plasminogen deficiency) Evaluating fibrinolysis, in combination with other components of the fibrinolytic system (fibrinogen, tissue...
PLHBB - Overview: Plasma Free Hemoglobin, Plasma
Determining whether hemolysis is occurring such as from: -Transfusion reaction -Mechanical fragmentation of red blood cells -Relative comparison to baseline levels in extracorporeal membrane oxygenation and centrifugal ventricular assist...
OCT4 - Overview: OCT3/4 Immunostain, Technical Component Only
Identification of germ cell tumors
PHTDP - Overview: Phosphorylated TDP43 Immunostain, Technical Component Only
Identification of pathological forms of TDP-43 in neurodegenerative diseases
POU2F - Overview: POU2F3 Immunostain, Technical Component Only
Diagnosis of a variant of small cell lung carcinoma
PAS8 - Overview: Pediatric Allergy Screen >8 Years, Serum
Establishing a diagnosis of an allergy to pediatric allergy screen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
PAS38 - Overview: Pediatric Allergy Screen 3 to 8 Years, Serum
Establishing a diagnosis of an allergy to pediatric allergy screen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum
Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.
TFE3I - Overview: Transcription Factor E3 (TFE3) Immunostain, Technical Component Only
Assessment of transcription factor E3 expression
TIS - Overview: Titanium, Serum
Monitoring metallic prosthetic implant wear
VIPI - Overview: Vasoactive Intestine Polypeptide (VIP), Technical Component Only
Aiding in the identification of islet cell tumors
RALB1 - Overview: Albumin, Random, Urine
Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens
AMMO - Overview: Ammonium, 24 Hour, Urine
Diagnosis of the cause of acidosis Diagnosis and treatment of kidney stones
CD273 - Overview: CD273 (PD-L2) Immunostain, Technical Component Only
Differentiation of primary mediastinal large B-cell lymphoma from diffuse large B cell-lymphoma
PACPI - Overview: Prostatic Acid Phosphatase (PACP) Immunostain, Technical Component Only
Identification of normal prostatic epithelium and prostatic adenocarcinoma
PSAIM - Overview: Prostate Specific Antigen (PSA) Immunostain, Technical Component Only
Marker of glandular epithelium in normal and neoplastic prostate
CD13 - Overview: CD13 Immunostain, Technical Component Only
Marker of myeloid lineage
HBELI - Overview: Hemoglobin Electrophoresis Interpretation
Interpretation for the results of hemoglobin electrophoresis Diagnosis and classification of hemoglobin disorders, including thalassemias and hemoglobin variants
PALD - Overview: Aldosterone, Plasma
Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...
AMYPI - Overview: Amyloid P (SAP) Immunostain, Technical Component Only
Identification of amyloid deposits in tissue
SOX11 - Overview: SOX11 Immunostain, Technical Component Only
Identification of mantle cell lymphomas
TSH - Overview: Thyroid-Stimulating Hormone (TSH), Beta Immunostain, Technical Component Only
Part of a panel of immunostains used in the classification of pituitary adenomas
HNF1B - Overview: Hepatocyte Nuclear Factor 1Beta Immunostain, Technical Component Only
Diagnosis of ovarian clear cell carcinoma and endometrial clear cell carcinoma
HALO - Overview: Haloperidol, Serum
Optimizing haloperidol dosage Monitoring patient compliance Assessing toxicity
GATA3 - Overview: GATA Binding Protein 3 Immunostain, Technical Component Only
Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors
GALN3 - Overview: Galectin-3 Immunostain, Technical Component Only
Distinguishing normal and benign thyroid gland from thyroid carcinoma
Classification of pituitary adenomas
EXT2 - Overview: Exostosin 2 (EXT2) Immunostain, Technical Component Only
Identification of exostosin 2 associated membranous nephropathy
IGAI - Overview: IgA Immunostain, Technical Component Only
Aiding in the classification of lymphomas and multiple myeloma
KIMEL - Overview: Ki67 + Melan A Immunostain, Technical Component Only
Ki67 is a marker of proliferation in neoplasms Melan A aids in the identification of melanoma
KRTAE - Overview: Keratin (AE1/AE3) Immunostain, Technical Component Only
Identification of cells expressing a broad spectrum of cytokeratins (low and high molecular weight keratins)
KRT5 - Overview: Keratin 5 (KRT5) Immunostain, Technical Component Only
Differentiation of mesothelioma and squamous cell carcinoma versus adenocarcinoma
INHIB - Overview: Inhibin Immunostain, Technical Component Only
Identifying sex cord-stromal tumors
MTAP - Overview: Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only
Aiding in the diagnosis of malignant mesothelioma
APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only
Aids in the identification of amyloid precursor protein present in Alzheimer disease
AAH - Overview: Amyloid A (Hepatic) Immunostain, Technical Component Only
Classification of hepatic adenomas This test is not useful for amyloid typing.
AFSH - Overview: Alpha Follicle Stimulating Hormone Immunostain, Technical Component Only
May aid in the classification of pituitary adenomas
BRAFV - Overview: BRAF V600E Immunostain, Technical Component Only
Identification of BRAF V600E-mutated protein
BHSF - Overview: Beta-Human Chorionic Gonadotropin, Quantitative, Spinal Fluid
Aiding in the diagnosis of brain metastases of testicular cancer or extragonadal intracerebral germ cell tumors
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.