ACMA - Overview: Acetaminophen, Serum

Monitoring toxicity in overdose cases

DOXA1 - Overview: Oxalate Analysis, Hemodialysate

Determining the amount of oxalate removed during a dialysis session Individualizing the dialysis prescription of hyperoxaluric patients

TPI1 - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

U1A1Q - Overview: Uridine Diphosphate (UDP) Glucuronosyltransferase 1A1 TA Repeat Genotype, UGT1A1, Varies

Identifying individuals who are at increased risk of adverse drug reactions with drugs that are metabolized by uridine diphosphate glucuronosyltransferase (UGT1A1); especially irinotecan but also atazanavir, nilotinib, pazopanib, and...

RPDE - Overview: Rapidly Progressive Dementia Evaluation, Spinal Fluid

Evaluation of individuals presenting with rapidly progressive dementia of uncertain disease etiology and a differential diagnosis of Creutzfeldt-Jakob disease and rapidly progressive Alzheimer disease

KETGP - Overview: Ketone Disorders Gene Panel, Varies

Follow up for abnormal biochemical results suggestive of a ketone disorder Establishing a molecular diagnosis for patients with ketone disorders Identifying variants within genes known to be associated with ketone disorders, allowing for...

APOA1 - Overview: Apolipoprotein A1, Serum

Evaluating risk for atherosclerotic cardiovascular disease Aiding in the detection of Tangier disease

MTXSG - Overview: Methotrexate Post Glucarpidase, Serum

Monitoring methotrexate concentrations post-glucarpidase therapy Documenting failure to respond that may be due to noncompliance Guiding dosage adjustments in patients with kidney failure

MONOS - Overview: Infectious Mononucleosis, Rapid Test, Serum

Diagnosis of Epstein-Barr virus mononucleosis

CCTR - Overview: Calcium/Creatinine Ratio, Random, Urine

Calculation of calcium concentration per creatinine concentration

URCU - Overview: Uric Acid, 24 Hour, Urine

Assessment and management of patients with kidney stones, particularly uric acid stones

RAMIK - Overview: Amikacin, Random, Serum

Monitoring adequacy of blood concentration during amikacin therapy

PAMIK - Overview: Amikacin, Peak, Serum

Monitoring adequacy of serum concentration during amikacin therapy

CH8B - Overview: Chromogenic Factor VIII Inhibitor Bethesda Titer, Plasma

Detecting the presence and titer of a specific factor inhibitor directed against coagulation factor VIII This test is not useful for detecting the presence of inhibitors directed against other clotting factors and will not detect the...

MPHNU - Overview: Methylphenidate and Metabolite, Random, Urine

Monitoring urine methylphenidate and ritalinic acid concentrations to assess compliance in patients

PACP - Overview: Prostatic Acid Phosphatase, Serum

Aiding in predicting recurrence after radical prostatectomy for clinically localized prostate cancer Following response to androgen ablation therapy, when used in conjunction with prostate-specific antigen

TLB - Overview: Thallium, Blood

Detecting toxic exposure in whole blood specimens

SORBU - Overview: Sorbitol and Mannitol, Quantitative, Random, Urine

Monitoring effectiveness of treatment in patients with phosphomannomutase 2 deficiency (PMM2-CDG) Establishing a baseline level prior to initiating treatment for PMM2-CDG This test is not useful for diagnosing congenital disorders of...

TRMP - Overview: Trimipramine, Serum

Monitoring trimipramine concentration during therapy Evaluating potential trimipramine toxicity May aid in evaluating patient compliance

ALC - Overview: Ethanol, Blood

Detection of ethanol (ethyl alcohol) in blood to document prior consumption or administration of ethanol Quantification of the concentration of ethanol in blood correlates directly with degree of intoxication This test is not intended for...

POU - Overview: Phosphorus, 24 Hour, Urine

Evaluation of hypo- or hyper-phosphatemic states Evaluation of patients with nephrolithiasis

PA - Overview: Procainamide and N-Acetylprocainamide, Serum

Monitoring therapy with procainamide Assessing compliance Evaluating procainamide toxicity

SDEX - Overview: Sickle Solubility, Blood

Screening for presence or absence of hemoglobin (Hb) S (sickle cell disease)

VALPF - Overview: Valproic Acid, Free, Serum

Monitoring free valproic acid in therapy Assessing compliance Evaluating potential toxicity

ACE - Overview: Angiotensin Converting Enzyme, Serum

Evaluation of patients with suspected sarcoidosis

TAMIK - Overview: Amikacin, Trough, Serum

Monitoring adequate clearance of amikacin near the end of a dosing cycle

BIOTN - Overview: Biotin, Serum

Measurement of biotin in serum Assessment of biotin concentrations in individuals taking biotin supplements Investigation of unexpected results from immunoassays that utilize biotin-streptavidin detection methods This test is not useful...

CLU - Overview: Chloride, 24 Hour, Urine

Indication of fluid balance and acid-base homeostasis using a 24-hour urine collection

KUR - Overview: Potassium, 24 Hour, Urine

Determining the cause for hyper- or hypokalemia

PBR - Overview: Phenobarbital, Serum

Monitoring for appropriate therapeutic concentration of phenobarbital Assessing compliance or toxicity

DLAU - Overview: D-Lactate, Urine

Preferred test for diagnosing D-lactate acidosis, especially in patients with jejunoileal bypass and short-bowel syndrome

BARTB - Overview: Bartonella, Molecular Detection, PCR, Blood

Aiding in the diagnosis of Bartonella infection when Bartonella DNA would be expected to be present in blood, especially endocarditis

LEIS - Overview: Leishmaniasis (Visceral) Antibody, Serum

Aiding in the diagnosis of active visceral leishmaniasis This test should not be used as the sole criteria for diagnosis.

HGCU - Overview: Mercury/Creatinine Ratio, Random, Urine

Detecting mercury toxicity using random urine specimens

SAT - Overview: Percent Saturation

Calculation of percent saturation

TPIC - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

MAGES - Overview: Myelin-Associated Glycoprotein Autoantibodies, IgM, Serum

Evaluating peripheral neuropathy Evaluating paraproteinemic neuropathy

PAC1 - Overview: Paraneoplastic, Autoantibody Evaluation, Spinal Fluid

Aiding in the diagnosis of paraneoplastic neurological autoimmune disorders related to carcinoma of lung, breast, ovary, thymoma, or Hodgkin lymphoma using spinal fluid specimens

SSH24 - Overview: Supersaturation Profile, Self-Collect, 24 Hour, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available -May aid in designing a treatment program Aiding...

ADEVL - Overview: Alzheimer Disease Evaluation, Spinal Fluid

Assessment of adults with cognitive impairment being evaluated for Alzheimer disease and other causes of cognitive impairment These assays should not be used to predict the development of dementia or other neurologic conditions or to...

BWRS - Overview: Beckwith-Wiedemann Syndrome/Russell-Silver Syndrome, Molecular Analysis, Varies

Confirming a clinical diagnosis of Beckwith-Wiedemann syndrome (BWS) or Russell-Silver syndrome (RSS) Prenatal diagnosis if there is a high suspicion of BWS/RSS based on ultrasound findings or in families at risk for BWS/RSS This assay...

QUAD1 - Overview: Quad Screen (Second Trimester) Maternal, Serum

Prenatal screening for open neural tube defect (alpha-fetoprotein only), trisomy 21 (alpha-fetoprotein, human chorionic gonadotropin, estriol, and inhibin A) and trisomy 18 (alpha-fetoprotein, human chorionic gonadotropin, and estriol)

FENTS - Overview: Fentanyl, Serum

Monitoring fentanyl therapy

5BETH - Overview: Factor V Bethesda Units, Plasma

Detecting and quantifying the presence and titer of a specific factor inhibitor directed against coagulation factor V

GBETH - Overview: General Factor Bethesda Units, Plasma

Detecting and quantifying the presence and titer of a specific factor inhibitor directed against a specific coagulation factor

C2FXN - Overview: C2 Complement, Functional, Serum

Investigation of a patient with a low (absent) hemolytic complement

MTHX - Overview: Methotrexate, Serum

Determining whether methotrexate is being cleared appropriately and verifying that a nontoxic concentration has been attained following therapy

ALP - Overview: Alkaline Phosphatase, Serum

Diagnosing and monitoring treatment of liver, bone, intestinal, and parathyroid diseases

A2PI - Overview: Alpha-2 Plasmin Inhibitor, Plasma

Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare) Providing a complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when...

CA - Overview: Calcium, Total, Serum

Diagnosis and monitoring of a wide range of disorders including diseases of bone, kidney, parathyroid gland, or gastrointestinal tract