Detection of RUNX1-RUNX1T1 gene fusion in acute myeloid leukemia patients at the time of diagnosis Minimal residual disease monitoring during the clinical and therapeutic course of these patients
ROMA - Overview: ROMA Score (Ovarian Malignancy Risk Algorithm), Serum
Risk assessment for finding an ovarian malignancy during surgery in women who present with an adnexal mass The test is not intended as a screening or stand-alone diagnostic assay for ovarian cancer.
RNP - Overview: RNP Antibodies, IgG, Serum
Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...
SSB - Overview: SS-B/La Antibodies, IgG, Serum
Evaluating patients with clinical features or at-risk for connective tissue disease, especially Sjögren syndrome.
UPGDW - Overview: Uroporphyrinogen Decarboxylase, Washed Erythrocytes
Diagnosis of porphyria cutanea tarda type II and hepatoerythropoietic porphyria
HPP12 - Overview: HIV-1/HIV-2 RNA Detection Prenatal, Plasma
Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals with indeterminate or inconclusive HIV serologic test results Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals in the acute or early phase of HIV-1 and/or...
HPS12 - Overview: HIV-1/HIV-2 RNA Detection Prenatal, Serum
Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals with indeterminate or inconclusive HIV serologic test results Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals in the acute or early phase of HIV-1 and/or...
EAG - Overview: Hepatitis B Virus e Antigen, Serum
Determining the presence or absence of detectable hepatitis B virus e antigen in monitoring infection status of individuals with chronic hepatitis B Determining infectivity of hepatitis B virus (HBV) carriers Monitoring serologic...
HEAB - Overview: Hepatitis B Virus e Antibody, Serum
Determining the presence or absence of detectable hepatitis B virus e antibody in monitoring infection status of individuals with chronic hepatitis B Determining infectivity of hepatitis B virus (HBV) carriers Monitoring serologic...
INHA - Overview: Inhibin A, Tumor Marker, Serum
Aiding in the diagnosis of patients with granulosa cell tumors of the ovary when used in combination with inhibin B Monitoring of patients with granulosa cell tumors and epithelial mucinous-type tumors of the ovary known to secrete inhibin...
HEX4 - Overview: Glucotetrasaccharides, Random, Urine
Diagnosing Pompe disease, when used in conjunction with acid alpha-glucosidase enzyme activity assays and molecular genetic analysis of the GAA gene Monitoring patients with Pompe disease on enzyme replacement therapy May support the...
FOBT - Overview: Fecal Occult Blood, Colorectal Cancer Screen, Qualitative, Immunochemical, Feces
Colorectal cancer screening Screening for gastrointestinal bleeding This test has not been validated for testing of patients with hemoglobinopathies.
HBIM - Overview: Hepatitis B Virus Core IgM Antibody, Serum
Diagnosis of acute hepatitis B virus (HBV) infection Identifying acute HBV infection in the serologic window period when hepatitis B virus surface antigen and hepatitis B virus surface antibody results are negative Differentiation...
ERPR - Overview: Estrogen/Progesterone Receptor, Semi-Quantitative Immunohistochemistry, Manual
Guiding decisions on hormonal therapy in patients with breast carcinomas This test is not useful for cases of lobular carcinoma in situ.
FRTUP - Overview: Free Thyroxine Index (FTI), Serum
Estimating the amount of circulating free thyroxine (free thyroxine index) using the total thyroxine and thyroid binding capacity (T-uptake)
IBDP2 - Overview: Inflammatory Bowel Disease Serology Panel, Serum
Distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations This test is not useful for determining the extent of disease in...
LHPED - Overview: Luteinizing Hormone (LH), Pediatrics, Serum
Diagnosis of precocious puberty and delayed puberty in children
AH50 - Overview: Alternative Complement Pathway, Functional, Serum
Investigation of suspected alternative pathway complement deficiency, atypical hemolytic uremic syndrome, C3 glomerulonephritis, and dense-deposit disease
ALADW - Overview: Aminolevulinic Acid Dehydratase, Washed Erythrocytes
Confirmation of a diagnosis of aminolevulinic acid dehydratase deficiency porphyria using washed erythrocyte specimens This test is not useful for detecting lead intoxication.
Diagnosing autoimmune lymphoproliferative syndrome, primarily in patients younger than 45 years
BRAFD - Overview: BRAF V600E/V600K Somatic Mutation Analysis, Tumor
Therapy selection for patients with cancer (eg, melanomas that may respond to BRAF inhibitors, colon cancers that may not respond to EGFR inhibitors) Aiding in the diagnosis/prognosis of certain cancers (eg, hairy cell leukemia, papillary...
SAFB - Overview: Acid-Fast Smear for Mycobacterium, Varies
Detection of acid-fast bacilli in clinical samples
Aids in monitoring a previously confirmed diagnosis of B-cell acute lymphoblastic leukemia
PBKQN - Overview: BK Virus DNA Detection and Quantification, Plasma
Detection and serial monitoring of BK virus-associated nephropathy in kidney transplant recipients using plasma specimens Detection and serial monitoring of BK virus-associated hemorrhagic cystitis in organ transplant recipients
CMVLR - Overview: Cytomegalovirus (CMV) Molecular Detection, PCR, Lower Respiratory
Rapid qualitative detection of cytomegalovirus (CMV) DNA in lower respiratory specimens This test is not intended for the monitoring of CMV disease progression or response to therapy.
LCMSP - Overview: Microsporidia species, Molecular Detection, PCR, Varies
Detecting Enterocytozoon bieneusi and Encephalitozoon species in fecal and urine specimens to support the clinical diagnosis of microsporidiosis
MATCC - Overview: Maternal Cell Contamination, Molecular Analysis, Varies
Ruling out the presence of maternal cell contamination within a fetal specimen Required for all prenatal testing performed in Mayo Clinic Laboratories' Molecular and Biochemical Genetics laboratories
Detection of severe respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19) in formalin-fixed, paraffin-embedded tissue
TWRP - Overview: Tropheryma whipplei, Molecular Detection, PCR, Varies
Aiding in the diagnosis of Whipple disease, especially for identifying inconclusive or suspicious cases, using tissue or fluid specimens
SHIGC - Overview: Shigella Culture, Feces
Determining whether Shigella species may be the cause of diarrhea Reflexive testing for Shigella species from nucleic acid amplification test-positive stool This test is generally not useful for patients hospitalized more than 3 days...
Detection of CBFB::MYH11 gene fusion in patients recently diagnosed with acute myeloid leukemia (AML) Minimal residual disease monitoring during the clinical and therapeutic course of patients with AML
CRAV - Overview: Cortisol, Right Adrenal Vein, Serum
Testing cortisol levels in the right adrenal vein Second-order testing when cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...
CTXP - Overview: Cerebrotendinous Xanthomatosis, Plasma
Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using plasma specimens Monitoring of individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the identification of...
COWB - Overview: Cobalt, Blood
Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.
DBS1 - Overview: Diabetes Mellitus Type 1 Evaluation, Serum
Distinguishing type 1 from type 2 diabetes mellitus Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Predicting future insulin requirement treatment in patients with adult-onset...
E157C - Overview: Escherichia coli O157:H7 Culture, Feces
Determining whether Escherichia coli O157:H7 may be the cause of diarrhea Reflexive testing for Shiga toxin and/or E coli O157:H7 nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized...
BPAB - Overview: Bullous Pemphigoid, BP180 and BP230, IgG Antibodies, Serum
Initial screening test in the diagnosis of bullous pemphigoid and its variants Complementing the standard serum test of indirect immunofluorescence utilizing primate esophagus substrate and primate salt-split skin substrate (CIFS /...
PBGDW - Overview: Porphobilinogen Deaminase, Washed Erythrocytes
Confirmation of a diagnosis of acute intermittent porphyria using washed erythrocyte specimens
ANIDE - Overview: Organism Referred for Identification, Anaerobic Bacteria
Identifying anaerobic bacteria involved in human infections
KRASD - Overview: Cell-Free DNA KRAS 12, 13, 61,146, Blood
An alternative to invasive tissue biopsies for the determination of KRAS 12, 13, 61,146 (G12A, G12C, G12D, G12R, G12S, G12V, G13D, Q61K, Q61L, Q61R, Q61H, and A146T) mutation status Detecting molecular markers associated with response or...
CIVC - Overview: Cortisol, Inferior Vena Cava, Serum
Testing cortisol levels in the inferior vena cava Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...
PREGN - Overview: Pregnenolone, Serum
An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency
SFGP - Overview: Spotted Fever Group Antibody, IgG and IgM, Serum
Aiding in the diagnosis of spotted fever group rickettsial infections
RNAP - Overview: RNA Polymerase III Antibodies, IgG, Serum
Evaluating patients suspected of having systemic sclerosis as part of systemic sclerosis criteria antibody tests Providing diagnostic and prognostic information in patients with systemic sclerosis
CLAV - Overview: Cortisol, Left Adrenal Vein, Serum
Testing cortisol levels in the left adrenal vein Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...
YERSC - Overview: Yersinia Culture, Feces
Determining whether Yersinia species may be the cause of diarrhea Reflexive testing for Yersinia species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than 3 days...
PUPYP - Overview: Purines and Pyrimidines Panel, Plasma
Evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism Monitoring patients with disorders of purine and pyrimidine metabolism Laboratory evaluation of primary and secondary hyperuricemias Assessing...
VHLE - Overview: VHL Gene, Erythrocytosis, Mutation Analysis, Varies
Diagnosis of suspected JAK2-negative VHL-related erythrocytosis associated with lifelong sustained increased RBC mass, elevated RBC count, hemoglobin, or hematocrit
23BPT - Overview: 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, 24 Hour, Urine
Screening for mast cell activation disorders including systemic mastocytosis using 24-hour urine specimens
URRP - Overview: Ureaplasma species, Molecular Detection, PCR, Varies
Rapid, sensitive, and specific identification of Ureaplasma urealyticum and Ureaplasma parvum from genitourinary, reproductive, bone, spine, joint, and lower respiratory sources This test is not intended for medicolegal use.
Learn how our cystatin C testing provides an index of glomerular filtration rate, which is the best indicator of overall kidney health and function....
Hepatitis C Virus Genotypic Antiviral Drug Resistance [Test in Focus] - Insights
Joseph Yao, M.D., gives an overview of this new test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be...
testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf
Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...
https://news.mayocliniclabs.com/mc2775-782/
FO U R RE AL -W O RL D C O LL AB O RA TI VE E XA M PL ES to Mayo Clinic diagnostics C O N N E C T I N G Pharma and biotech TABLE OF CONTENTS What makes a good testing partner? Case study 1 Gastrointestinal...
Algorithms - Mayo Clinic Laboratories
Algorithms A B C D E F G H I J