PCPDS - Overview: Plasma Cell Proliferative Disorder, High Risk with Reflex Probes, Diagnostic FISH Evaluation, Bone Marrow

Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders using bone marrow specimens Identifying prognostic markers based on the abnormalities found This test should not be used to track the...

CLPMG - Overview: Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum

The following clinical situations: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature...

PATHC - Overview: Pathology Consultation

A subspecialty second opinion for a specific pathology question referred by a primary pathologist Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP...

NGPCM - Overview: MayoComplete Plasma Cell Myeloma, Next-Generation Sequencing, Varies

Evaluating multiple myeloma at the time of diagnosis and at disease relapse or when changing clinical management to provide prognostic information and determine potential therapeutic implications

INFXR - Overview: Infliximab Quantitation with Reflex to Antibodies to Infliximab, Serum

Trough level quantitation for evaluation of patients undergoing therapy with infliximab, with signs and symptoms of loss of response to therapy.

SMCP - Overview: Inherited Skeletal Muscle Channelopathy Gene Panel, Varies

Establishing a molecular diagnosis for patients with a skeletal muscle channelopathy Identifying variants within genes known to be associated with a skeletal muscle channelopathy allowing for predictive testing of at-risk family members

ROMA1 - Overview: Risk Score, if Premenopausal, Serum

Calculating risk assessment for finding an ovarian malignancy during surgery in premenopausal women who present with an adnexal mass

FFTEN - Overview: Tetrahydrobiopterin and Neopterin Profile (BH4, N)

Tetrahydrobiopterin and Neopterin Profile (BH4, N)

CRSBF - Overview: Crystal Identification, Body Fluid

Identifying the presence and type of crystals in body fluid

CSU - Overview: Chyluria Screen, Random, Urine

Aiding in the diagnosis of chyluria (galacturia)

FNEU - Overview: Neurotransmitter Metabolites (5HIAA, HVA, 3OMD) (CSF)

Neurotransmitter Metabolites (5HIAA, HVA, 3OMD) (CSF)

PBNA - Overview: Lead, Nails

Detecting lead exposure using nail specimens

THSIF - Overview: Thrombospondin Type 1 Domain Containing 7A (THSD7A), Immunofluorescence

Diagnosis of thrombospondin type 1 domain-containing 7A (THSD7A)-associated membranous nephropathy

DHRP - Overview: Dihydrorhodamine Flow Cytometric Phorbol Myristate Acetate Test, Blood

Evaluating chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, complete myeloperoxidase deficiency Monitoring chimerism and nicotinamide adenine dinucleotide phosphate oxidase (NOX) function post-hematopoietic cell...

INFXP - Overview: Infliximab Quantitation with Antibodies to Infliximab, Serum

Trough level quantitation for evaluation of patients undergoing therapy with infliximab for proactive or reactive therapeutic drug monitoring.

NTC3Z - Overview: NOTCH3 Gene, Full Gene Analysis, Varies

Establishing a molecular diagnosis in individuals with features of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and NOTCH3-related disorders Identifying disease-causing variants...

PBCPN - Overview: Primary Biliary Cholangitis Antibody Panel, Serum

Evaluation of at-risk or previously diagnosed primary biliary cholangitis patients with new features of other liver diseases or systemic autoimmune diseases

PNEFC - Overview: Neuroimmunology Antibody Follow-up, Spinal Fluid

Monitoring patients who have previously tested positive for 1 or more antibodies within the past 5 years in a Mayo Clinic Neuroimmunology Laboratory spinal fluid evaluation

SMNDX - Overview: Spinal Muscular Atrophy Diagnostic Assay, Deletion/Duplication Analysis, Varies

First-tier newborn screening for spinal muscular atrophy (SMA) Prenatal testing for SMA Diagnostic testing to confirm a suspected diagnosis of SMA

HK1 - Overview: Hexokinase Enzyme Activity, Blood

The evaluation of individuals with Coombs-negative chronic hemolysis

HKC - Overview: Hexokinase Enzyme Activity, Blood

The evaluation of individuals with Coombs-negative chronic hemolysis

23FBG - Overview: Fibroblast Growth Factor-23 (FGF23), In Situ Hybridization

Assessing fibroblast growth factor-23 (FGF23) expression

PBHA - Overview: Lead, Hair

Detecting lead exposure using hair specimens

LITH - Overview: Lithium, Serum

Monitoring therapy of patients with bipolar disorders, including recurrent episodes of mania and depression Evaluating lithium toxicity

MEX - Overview: Mexiletine, Serum

Assessing achievement of optimal therapeutic mexiletine concentrations Assessing potential mexiletine toxicity

PFN - Overview: Propafenone, Serum

Monitoring propafenone therapy Assessing potential propafenone toxicity

TMP - Overview: Trimethoprim, Serum

Monitoring trimethoprim therapy to ensure drug absorption, clearance, or compliance

FPAN2 - Overview: Pancreastatin, Plasma

Pancreastatin, Plasma

PERAM - Overview: Perampanel, Serum

Monitoring serum concentration of perampanel, in specific clinical conditions (ie, severe kidney impairment, mild to moderate hepatic impairment, and end-stage kidney disease) Assessing compliance Assessing potential toxicity

FLEC - Overview: Flecainide, Serum

Optimizing flecainide dosage Assessing flecainide toxicity Monitoring compliance

CILPF - Overview: Congenital Infantile Leukemia, FISH, Tissue

Detecting a neoplastic clone associated with the common chromosome abnormalities and classic rearrangements seen in infant patients with leukemia using tissue specimens

COKEU - Overview: Cocaine and Metabolite Confirmation, Random, Urine

Detecting and confirming drug abuse involving cocaine This test is not intended for employment-related testing.

DEXA - Overview: Dexamethasone, Serum

Confirming the presence of dexamethasone in serum Confirming the cause of secondary adrenal insufficiency This test is not useful as the sole basis for a diagnosis or treatment decisions.

5BETH - Overview: Factor V Bethesda Units, Plasma

Detecting and quantifying the presence and titer of a specific factor inhibitor directed against coagulation factor V

AFOLR - Overview: Folate Receptor Alpha (FOLR1), Semi-Quantitative Immunohistochemistry, Manual

Diagnosis of epithelial ovarian cancer that may be eligible for treatment with an anti-folate receptor 1 protein antibody

KIBM - Overview: Ki-67(MIB-1), Breast, Semi-Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma

SDEX - Overview: Sickle Solubility, Blood

Screening for presence or absence of hemoglobin (Hb) S (sickle cell disease)

CSPMM - Overview: Plasma Cell Myeloma Pre-Analysis Cell Sorting, Bone Marrow

Pre-analysis cell sorting for the MayoComplete Plasma Cell Myeloma panel

TRYPU - Overview: Tryptophan, Random, Urine

Aiding in the screening and monitoring of Hartnup disease

COGMF - Overview: Acute Myeloid Leukemia (AML), Children's Oncology Group Enrollment Testing, FISH, Varies

Evaluation of pediatric bone marrow and peripheral blood specimens by fluorescence in situ hybridization (FISH) probe analysis for classic rearrangements and chromosomal copy number changes associated with acute myeloid leukemia (AML) in...

AMLMF - Overview: Acute Myeloid Leukemia (AML), Specified FISH, Varies

Detecting recurrent common chromosome abnormalities seen in patients with acute myeloid leukemia (AML) using a client-specified probe set An adjunct to chromosome studies in patients with AML Evaluating specimens in which chromosome...

DHR - Overview: Dihydrorhodamine Flow Cytometric Test, Blood

Evaluation of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, Rac2 deficiency, complete myeloperoxidase deficiency Monitoring chimerism and nicotinamide adenine dinucleotide phosphate oxidase (NOX) function...

ALPSG - Overview: Autoimmune Lymphoproliferative Syndrome (ALPS) Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of autoimmune lymphoproliferative syndrome (ALPS) or related disorders Establishing a diagnosis of ALPS or a related disorder, allowing...

APOA1 - Overview: Apolipoprotein A1, Serum

Evaluating risk for atherosclerotic cardiovascular disease Aiding in the detection of Tangier disease

AC1Q - Overview: Anti-C1q Antibodies, IgG, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus Detection of anti-C1q antibodies in serum

RAMBO - Overview: Ammonium, Random, Urine

Diagnosis of the cause of acidosis using random urine specimens Diagnosis and treatment of kidney stones

VITC - Overview: Ascorbic Acid (Vitamin C), Plasma

Identifying vitamin C deficiency

ANNEX - Overview: Annexin-1 Immunostain, Technical Component Only

Classification of leukemias

AMS - Overview: Amylase, Total, Serum

Diagnosis and management of pancreatitis Evaluation of pancreatic function

A2PI - Overview: Alpha-2 Plasmin Inhibitor, Plasma

Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare) Providing a complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when...