INHIB - Overview: Inhibin Immunostain, Technical Component Only

Identifying sex cord-stromal tumors

UIOD - Overview: Iodine, 24 Hour, Urine

Assessing iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy

LACTO - Overview: Lactotransferrin Immunostain, Technical Component Only

Identifying the presence of lactotransferrin in amyloid deposits An adjunct to amyloid-subtyping analysis by mass spectrometry

MTAP - Overview: Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only

Aiding in the diagnosis of malignant mesothelioma

AFPPT - Overview: Alpha-Fetoprotein (AFP), Peritoneal Fluid

An adjunct to cytology to differentiate between malignancy-related ascites and benign causes of ascites formation

ADMA - Overview: Asymmetric Dimethylarginine, Plasma

Assessing the likelihood of future coronary events in patients with coronary heart disease, type II diabetes mellitus, or kidney disease Prompting intervention and assessing improvements among subjects with elevated ADMA and...

BRAFV - Overview: BRAF V600E Immunostain, Technical Component Only

Identification of BRAF V600E-mutated protein

BCOR - Overview: BCOR Immunostain, Technical Component Only

Aiding in the distinction of a subset of primitive round cell sarcomas with BCOR rearrangements from other Ewing/Ewing-like sarcomas

B2MC - Overview: Beta-2-Microglobulin (Beta-2-M), Spinal Fluid

Evaluation of central nervous system inflammation and B-cell proliferative diseases

BETA2 - Overview: Beta-2 Transferrin: Detection of Spinal Fluid in Other Body Fluid

Detection of spinal fluid in body fluids, such as ear or nasal fluid

C9FX - Overview: C9 Complement, Functional, Serum

Diagnosis of C9 deficiency Investigation of a patient with a low total (hemolytic) complement level

CRMWS - Overview: Collapsin Response-Mediator Protein-5-IgG, Western Blot, Serum

Evaluation of cases of chorea, vision loss, cranial neuropathy and myelopathy

NEUD1 - Overview: Neuronal Differentiation 1 (NeuroD1), Technical Component only

Subclassification of small cell lung carcinoma

FMSS2 - Overview: Maternal Serum Screening, Integrated, Specimen #2, Alpha Fetoprotein, Hcg, Estriol, and Inhibin A

Helpful to identify pregnancies at increased risk of having a child with Down syndrome (trisomy 21), Open Neural Tube Defect (ONTD, spina bifida) and trisomy 18 (T18). This test is not diagnostic. The patient information provided with the...

PRMB - Overview: Primidone and Phenobarbital, Serum

Assessing compliance Monitoring for appropriate therapeutic levels of primidone and phenobarbital Assessing toxicity

SGSS - Overview: Synthetic Glucocorticoid Screen, Serum

Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.

S100 - Overview: S-100 Immunostain, Technical Component Only

Aids in the identification of various neoplasms

SSX18 - Overview: Synovial Sarcoma Panel, Technical Component Only

Aiding in distinguishing synovial sarcomas from similar sarcomas

CDUCR - Overview: Cadmium/Creatinine Ratio, Random, Urine

Detecting exposure to cadmium, a toxic heavy metal, using random urine specimens

FXCH - Overview: Coagulation Factor X Chromogenic Activity Assay, Plasma

Monitoring warfarin anticoagulant therapy, especially in patients whose plasma contains lupus anticoagulants that interfere with baseline prothrombin time/international normalized ratio and in patients receiving the drug Argatroban who are...

CONCS - Overview: Contactin-1 IgG Cell Binding Assay, Serum

Evaluating for chronic inflammatory demyelinating polyradiculoneuropathy and related demyelinating peripheral neuropathies Determining contactin-1 IgG results as a part of a profile

CLZ - Overview: Clozapine, Serum

Monitoring patient compliance of clozapine treatment An aid to achieving desired serum levels

THCCU - Overview: Delta-9-Carboxy-Tetrahydrocannabinol Confirmation and Creatinine Ratio, Random, Urine

Measuring the delta-9 carboxy-tetrahydrocannabinol to creatinine ratio as a part of a profile

PTEM - Overview: Platelet Transmission Electron Microscopic Study, Whole Blood

Diagnosing platelet disorders

TTF40 - Overview: TTF41 (SPT24) + p40 Immunostain, Technical Component Only

Thyroid transcription factor 1 aids in the classification of carcinomas of unknown origin p40 aids in the classification of carcinomas and lymphomas

C5FX - Overview: C5 Complement, Functional, Serum

Diagnosis of C5 deficiency Investigation of a patient with an undetectable total complement level

C7FX - Overview: C7 Complement, Functional, Serum

Diagnosis of C7 deficiency Investigation of a patient with an undetectable total complement level

COM - Overview: Complement, Total, Serum

Detection of individuals with an ongoing immune process First-tier screening test for congenital complement deficiencies

C6FX - Overview: C6 Complement, Functional, Serum

Diagnosis of C6 deficiency Investigation of a patient with an undetectable total complement level

CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma

Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing

ASYNC - Overview: Alpha-Synuclein Protein Aggregates, Spinal Fluid

Detection of pathogenic alpha-synuclein (alpha-synuclein aggregates) in adult patients being assessed for clinically uncertain cognitive decline or clinically uncertain parkinsonian syndromes

PHI11 - Overview: Prostate Health Index Reflex, Serum

As an aid in distinguishing prostate cancer from benign prostatic conditions in men aged 50 years and older with total PSA between 4.0 and 10.0 ng/mL and digital rectal examination findings that are not suspicious for cancer

NMEM - Overview: Red Blood Cell Membrane Disorders Gene Panel, Next-Generation Sequencing, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of a red blood cell (RBC) membrane disorder Second-tier testing for patients in whom previous targeted gene variant analyses were...

PMCMG - Overview: Postmortem Cardiomyopathy Gene Panel, Tissue

Providing a comprehensive postmortem genetic evaluation in the setting of a sudden death attributed to cardiomyopathy or with a personal or family history suggestive of a hereditary form of cardiomyopathy Identifying a disease-causing...

BRGYP - Overview: Hereditary Breast/Gynecologic Cancer Panel, Varies

Evaluating patients with a personal or family history suggestive of a hereditary breast or gynecological cancer syndrome Establishing a diagnosis of a hereditary breast or gynecological cancer syndrome allowing for targeted cancer...

HPGLP - Overview: Hereditary Paraganglioma/Pheochromocytoma Panel, Varies

Evaluating patients with a personal or family history suggestive of a hereditary paraganglioma and pheochromocytoma (PGL/PCC) syndrome Establishing a diagnosis of a hereditary PGL/PCC, allowing for targeted surveillance based on...

MFRGG - Overview: Marfan, Loeys-Dietz, and Aortopathy Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of Marfan syndrome and related conditions Establishing a diagnosis for Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome,...

ANST - Overview: Androstenedione, Serum

Diagnosis and differential diagnosis of hyperandrogenism, in conjunction with measurements of other sex steroids Diagnosis of congenital adrenal hyperplasia (CAH), in conjunction with measurement of other androgenic precursors,...

GLICP - Overview: CD8 T-Cell Immune Competence Panel, Global, Whole Blood

Determining over immunosuppression within the CD8 T-cell compartment, when used on transplant recipients and patients with autoimmune disorders receiving therapy with immunosuppressant agents

WARSQ - Overview: Warfarin Response Genotype, Varies

Identifying patients who may require warfarin dosing adjustments(3,4) including: -Patients being started on a first prescription for warfarin -Patients who have previously been prescribed warfarin and have required multiple dosing...

CRCL - Overview: Creatinine Clearance, Serum and 24-Hour Urine

Estimation of glomerular filtration rate

IGFMS - Overview: Insulin-Like Growth Factor-1, Mass Spectrometry, Serum

Evaluation of growth disorders Evaluation of growth hormone deficiency or excess in children and adults Monitoring of recombinant human growth hormone treatment Follow-up of individuals with acromegaly and gigantism

MAS1 - Overview: Myelopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Evaluating patients with suspected autoimmune myelopathy, myelitis, and paraneoplastic myelopathy using serum specimens

GLIOF - Overview: 1p/19q Deletion in Gliomas, FISH, Tissue

Aids in diagnosing oligodendroglioma tumors and predicting the response of an oligodendroglioma to therapy May be useful in tumors with a complex "hybrid" morphology requiring differentiation from pure astrocytomas to support the presence...

CPAVP - Overview: Copeptin proAVP, Plasma

Investigating the differential diagnosis for patients with water balance disorders, including diabetes insipidus, in conjunction with osmolality and hydration status May aid in the evaluation of cardiovascular disease in conjunction with...

FQPPS - Overview: Porphyrins, Feces

Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked dominant...

HGEM - Overview: Hydroxyglutaric Acids, Glutaric Acid, Ethylmalonic Acid, and Methylsuccinic Acid, Blood Spot

Evaluation of patients with an abnormal newborn screen showing elevations of glutarylcarnitine (C5-DC) using dried blood spot specimens Evaluation of patients with abnormal newborn screens showing elevations of C4-acylcarnitine to aid in...

IDTRT - Overview: IDH1, IDH2, and TERT Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the IDH1 and IDH2 genes and the TERT promoter to assist in tumor diagnosis/classification

TFH - Overview: FH Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the FH gene to assist in tumor diagnosis/classification, including renal cell carcinoma, uterine/cutaneous leiomyoma, and pheochromocytoma/paraganglioma

IGGS - Overview: IgG Subclasses, Serum

Second-order testing for evaluation of patients with clinical signs and symptoms of humoral immunodeficiency or combined immunodeficiency (cellular and humoral)