SECOS - Overview: Secobarbital, Serum

Monitoring secobarbital therapy

RPHOC - Overview: Phosphorus, Random, Urine

Evaluation of hypo- or hyperphosphatemic states Evaluation of patients with nephrolithiasis

GNHMA - Overview: Hemophilia A, F8 Gene, Next-Generation Sequencing, Varies

Confirming a clinical diagnosis of hemophilia A in affected male patients with the identification of a disease-causing variant in the F8 gene Determining the disease-causing alteration within the F8 gene to delineate the underlying...

SCIDP - Overview: Severe Combined Immunodeficiency (SCID) Gene Panel, Varies

Establishing a diagnosis of a severe combined immunodeficiency (SCID) associated with known causal genes Identifying variants within genes known to be associated with SCID, allowing for predictive testing of at-risk family members and/or...

HHTGG - Overview: Hereditary Hemorrhagic Telangiectasia and Vascular Malformations Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary hemorrhagic telangiectasia (HHT), cerebral cavernous malformation (CCM), capillary malformation-arteriovenous malformation syndrome...

INFXP - Overview: Infliximab Quantitation with Antibodies to Infliximab, Serum

Trough level quantitation for evaluation of patients undergoing therapy with infliximab for proactive or reactive therapeutic drug monitoring.

GNPRC - Overview: Protein C Deficiency, PROC Gene, Next-Generation Sequencing, Varies

Evaluating protein C deficiency in patients with a personal or family history suggestive of this hereditary thrombophilia Confirming a diagnosis of autosomal dominant protein C deficiency with the identification of a known or suspected...

NGSHM - Overview: MayoComplete Myeloid Neoplasms, Comprehensive OncoHeme Next-Generation Sequencing, Varies

Evaluation of known or suspected hematologic neoplasms, specifically of myeloid origin (eg, acute myeloid leukemia, myelodysplastic syndrome, myeloproliferative neoplasm, myelodysplastic/myeloproliferative neoplasm, unexplained cytopenias)...

TPNUQ - Overview: Thiopurine Methyltransferase (TPMT) and Nudix Hydrolase (NUDT15) Genotyping, Varies

Predicting potential for toxicity to thiopurine drugs (6-mercaptopurine, 6-thioguanine, and azathioprine)

TRECS - Overview: T-Cell Receptor Excision Circles Analysis, Blood

Measuring T-cell output or reconstitution (thymopoiesis) following hematopoietic cell transplantation or highly active antiretroviral therapy Evaluating thymic function in patients with cellular or combined inborn errors of immunity...

AGDD - Overview: Alpha Globin Cluster Locus Deletion/Duplication, Varies

Diagnosis of alpha-thalassemia Carrier screening for individuals from high-risk populations for alpha-thalassemia This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.

KETGP - Overview: Ketone Disorders Gene Panel, Varies

Follow up for abnormal biochemical results suggestive of a ketone disorder Establishing a molecular diagnosis for patients with ketone disorders Identifying variants within genes known to be associated with ketone disorders, allowing for...

CVHBG - Overview: Comprehensive Cerebrovascular Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of a monogenic condition in which there is an increased risk for a cerebrovascular accident Establishing a diagnosis of a monogenic condition in which...

BADX - Overview: BCR/ABL1, Qualitative, Diagnostic Assay, Varies

Diagnostic workup of patients with a high probability of BCR::ABL1-positive hematopoietic neoplasms, predominantly chronic myeloid leukemia and acute lymphoblastic leukemia

ARSU - Overview: Arylsulfatase A, 24 Hour, Urine

Detection of arylsulfatase A deficiency using urine specimens This test is not suitable for carrier detection.

MPS2Z - Overview: Hunter Syndrome, Full Gene Analysis, Varies

Confirmation of a diagnosis of mucopolysaccharidosis type II (Hunter syndrome) Carrier testing when there is a family history of mucopolysaccharidosis type II (Hunter syndrome), but disease-causing variants have not been previously...

CASHR - Overview: Cashew, IgE with Reflex to Cashew Component, IgE, Serum

Evaluation of patients with suspected cashew allergy

CHRHB - Overview: Chromosome Analysis, Hematologic Disorders, Blood

Assisting in the classification and follow-up of certain malignant hematological disorders when bone marrow is not available This test is not useful for congenital disorders.

GAL1P - Overview: Galactose-1-Phosphate, Erythrocytes

Monitoring dietary therapy of patients with galactosemia due to deficiency of galactose-1-phosphate uridyltransferase or uridine diphosphate galactose-4-epimerase

NAT2Q - Overview: N-Acetyltransferase 2 (NAT2) Genotype, Varies

Identifying patients who may be at risk for altered metabolism of drugs that are substrates of arylamine N-acetyltransferase type 2, including isoniazid

BRMLH - Overview: MLH1 Hypermethylation and BRAF Mutation Analysis, Tumor

An adjunct to MSI / Microsatellite Instability (MSI), Tumor and IHC / Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor testing, when colon tumor demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein...

PLAFL - Overview: Platelet Surface Glycoprotein by Flow Cytometry, Blood

Identification of markedly decreased CD41 (GPIIb) and CD61 (GPIIIa) expression levels, which are diagnostic for Glanzmann thrombasthenia Identification of markedly decreased CD42a (GPIX) and CD42b (GPIb-alpha) expression levels, which are...

RPR4 - Overview: Respiratory Profile, Region 4, Sub-tropic Florida (Florida S. of Orlando), Serum

Assessing sensitization to various inhalant allergens commonly found in sub-tropic Florida, which is south of Orlando Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic...

RPR3 - Overview: Respiratory Profile, Region 3, South Atlantic (GA, N.FA, SC), Serum

Assessing sensitization to various inhalant allergens commonly found in the South Atlantic region, including Georgia, Northern Florida, and South Carolina Defining the allergen responsible for eliciting signs and symptoms Identifying...

RPR6 - Overview: Respiratory Profile, Region 6, South Central (AL, AR, LA, MS), Serum

Assessing sensitization to various inhalant allergens commonly found in the South Central region including Alabama, Arkansas, Louisiana and Mississippi Defining the allergen responsible for eliciting signs and symptoms Identifying...

RPR1 - Overview: Respiratory Profile, Region 1, North Atlantic (CT, MA, ME, NJ, NH, NY, PA, RI, VT), Serum

Assessing sensitization to various inhalant allergens commonly found in the North Atlantic region including Connecticut, Maryland, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont Defining the allergen...

RPR2 - Overview: Respiratory Profile, Region 2, Mid-Atlantic (DC, DE, MD, NC, VA), Serum

Assessing sensitization to various inhalant allergens commonly found in the Mid-Atlantic region including the District of Columbia, Delaware, Maryland, North Carolina, and Virginia Defining the allergen responsible for eliciting signs and...

POLET - Overview: POLE Mutation Analysis, Next-Generation Sequencing, Tumor

Identifying specific mutations within the POLE gene to assist in tumor diagnosis/classification

PGRBC - Overview: Plasmalogens, Blood

Diagnosing patients with possible peroxisomal disorders, such as peroxisomal biogenesis disorders (Zellweger syndrome spectrum) and rhizomelic chondrodysplasia punctata (RCDP), including fatty acyl-CoA reductase 1 (FAR1) deficiency...

RPR10 - Overview: Respiratory Profile, Region 10, Southwestern Grasslands (OK, TX), Serum

Assessing sensitization to various inhalant allergens commonly found in the Southwestern Grasslands region, including Oklahoma and Texas Defining the allergen responsible for eliciting signs and symptoms Identifying...

RPR17 - Overview: Respiratory Profile, Region 17, Pacific Northwest (Northwestern CA, Western OR, WA), Serum

Assessing sensitization to various inhalant allergens commonly found in the Pacific Northwest including the region of Northwestern California, Western Oregon and Washington Defining the allergen responsible for eliciting signs and...

LMPP - Overview: Lipoprotein Metabolism Profile, Serum

Diagnosing dyslipoproteinemia Quantifying cholesterol and triglycerides in very-low-density lipoprotein, low-density lipoprotein (LDL), high-density lipoproteins (HDL), and chylomicrons Identifying lipoprotein-X Classifying...

LCAF - Overview: Lung Cancer, ALK (2p23) Rearrangement, FISH, Tissue

Identifying patients with non-small cell lung carcinoma who may benefit from treatment with directed tyrosine kinase inhibitors

MPNCM - Overview: Myeloproliferative Neoplasm, CALR with Reflex to MPL, Varies

Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm when JAK2V617F testing result is negative

UBA1Q - Overview: UBA1 Mutation Quantitative Detection, VEXAS syndrome, Droplet Digital PCR, Varies

Identification of pathogenic variant(s) in the UBA1 gene in patients presenting with symptoms concerning for or consistent with VEXAS syndrome

VEDOZ - Overview: Vedolizumab Quantitation with Antibodies, Serum

Assessing for primary or secondary loss of response to therapy with vedolizumab An aid to achieving desired serum concentrations of vedolizumab

FABRZ - Overview: Fabry Disease, Full Gene Analysis, Varies

Confirmation of a diagnosis of classic or variant Fabry disease in affected males with reduced alpha- galactosidase A enzyme activity Carrier or diagnostic testing for asymptomatic or symptomatic females, respectively

APGAL - Overview: Galactose-Alpha-1,3-Galactose (Alpha-Gal) Mammalian Meat Allergy Profile, Serum

As an aid in diagnosis of an IgE mediated hypersensitivity allergy to non-primate mammalian red meat, such as beef, pork, venison, and meat-derived products, such as gelatin, via allergen profile testing This test is not useful in...

FAPM - Overview: Fatty Acid Profile, Mitochondrial (C8-C18), Serum

Biochemical diagnosis of inborn errors of mitochondrial fatty acid oxidation, including deficiencies of medium-chain acyl-Co-A dehydrogenase, long-chain 3-hydroxyacyl-Co-A dehydrogenase, very long-chain acyl-Co-A dehydrogenase, and glutaric...

LY27B - Overview: HLA-B27, Blood

Assisting in the diagnostic process of ankylosing spondylitis, juvenile rheumatoid arthritis, and reactive arthritis

F8IS - Overview: Coagulation Factor VIII Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor VIII

CHCK - Overview: Chicken Feathers, IgE, Serum

Establishing a diagnosis of an allergy to chicken feathers Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...

CHLE - Overview: Cholesteryl Esters, Serum

Establishing a diagnosis of lecithin-cholesterol acyltransferase deficiency Evaluating the extent of metabolic disturbance by bile stasis or liver disease

NCDTC - Overview: Neurochondrin Antibody, Tissue Immunofluorescence Titer, Spinal Fluid

Detecting neurochondrin-IgG in spinal fluid (CSF) from patients presenting with cerebellar and brainstem syndrome Reporting an end titer result from CSF specimens

PEAR - Overview: Pear, IgE, Serum

Establishing a diagnosis of an allergy to pear Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...

PARVN - Overview: Parvovirus B19 Antibody, Technical Interpretation

Interpretation of serologic testing for recent or past parvovirus B19 infection This test is not useful as a screening procedure for the general population

POSV - Overview: Post Vasectomy Check, Semen

Determining absence or presence of sperm postvasectomy

PINW - Overview: Pinworm Exam, Perianal

Detection of the eggs of Enterobius vermicularis on the skin of the perianal folds

EURO - Overview: Phospholipase A2 Receptor, Enzyme Linked Immunosorbent Assay, Serum

Distinguishing primary from secondary membranous nephropathy

PLA2M - Overview: Phospholipase A2 Receptor, Monitoring, Enzyme-Linked Immunosorbent Assay, Serum

Distinguishing primary from secondary membranous nephropathy Monitoring patients with membranous nephropathy, over time, for trends in anti-phospholipase A2 receptor antibody levels