SYNAP - Overview: Synaptophysin (SYNAPTO) Immunostain, Technical Component Only
Identification of neuronal tumors and tumors with neuroendocrine differentiation
JAKXR - Overview: JAK2 Exon 12-15 Sequencing, Polycythemia Vera Reflex, Varies
Aiding in the distinction between the myeloproliferative neoplasm polycythemia vera (PV) and other secondary erythrocytosis Evaluating for mutations within exons 12 to 15 of JAK2 in an algorithmic process as part of PVJAK / Polycythemia...
COKEM - Overview: Cocaine and Metabolites Confirmation, Meconium
Detecting in utero drug exposure up to 5 months before birth
CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma
Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing
VITAP - Overview: Vitamin A, Serum
Diagnosing vitamin A deficiency and toxicity as a part of a profile Monitoring vitamin A therapy
ALCX - Overview: Ethanol, Chain of Custody, Blood
Detection of ethanol (ethyl alcohol) in blood to document prior consumption or administration of ethanol Quantification of the concentration of ethanol in blood correlates directly with degree of intoxication All testing is performed...
CA25 - Overview: Cancer Antigen 125 (CA 125), Serum
Evaluating individuals' response to ovarian cancer therapy Predicting recurrent ovarian cancer This test is not useful for cancer detection screening in the normal population.
OPATM - Overview: Opiate Confirmation, Meconium
Detecting maternal prenatal opiate/opioid use up to 5 months before birth
HBELI - Overview: Hemoglobin Electrophoresis Interpretation
Interpretation for the results of hemoglobin electrophoresis Diagnosis and classification of hemoglobin disorders, including thalassemias and hemoglobin variants
PCDES - Overview: Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum
Evaluating children with autoimmune central nervous system disorders using serum specimens
PCDEC - Overview: Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Spinal Fluid
Evaluating children with autoimmune central nervous system disorders using spinal fluid specimens
Evaluating congenital fibrinogen disorders (CFD) in patients with a personal or family history suggestive of a fibrinogen disorder Confirming a CFD diagnosis with the identification of known or suspected disease-causing alterations in the...
PNEFS - Overview: Neuroimmunology Antibody Follow-up, Serum
Monitoring patients who have previously tested positive for one or more antibodies within the past 5 years in a Mayo Neuroimmunology Laboratory serum evaluation
OPATU - Overview: Opiates Confirmation, Random, Urine
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
OXYSX - Overview: Oxycodone Screen, Chain of Custody, Random, Urine
Detection of oxycodone and oxymorphone in urine following chain-of-custody procedures This chain-of-custody test is intended to be used in a setting where the test results can be used definitively to make a diagnosis. Chain of custody is...
PCPMX - Overview: Phencyclidine (PCP) Confirmation, Chain of Custody, Meconium
Detection of in utero drug exposure up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen...
TDP - Overview: Thiamine (Vitamin B1), Whole Blood
Assessment of thiamine deficiency Measuring thiamine levels in patients with behavioral changes, eye signs, gait disturbances, delirium, and encephalopathy; or in patients with questionable nutritional status, especially those who appear...
BCGR - Overview: Immunoglobulin Gene Rearrangement, Blood
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...
VZPG - Overview: Varicella-Zoster Antibody, IgG, Serum
Determination of immune status of individuals to the varicella-zoster virus (VZV) Documentation of previous infection with VZV in an individual without a previous record of immunization to VZV
ETGX - Overview: Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine
Monitoring abstinence in clinical and justice system settings using ethyl glucuronide and ethyl sulfate as direct biomarkers or metabolites of ethanol This chain-of-custody test is intended to be used in a setting where the test results...
NIUCR - Overview: Nickel/Creatinine Ratio, Random, Urine
Preferred specimen type for biomonitoring nickel exposure
PCTTC - Overview: Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr) Titer, Spinal Fluid
Serological testing for Purkinje cell cytoplasmic antibody-Tr for patients with acquired cerebellar ataxia of undetermined etiology, particularly if the patient has a history of Hodgkin lymphoma Reporting an end titer result from spinal...
PU1 - Overview: PU.1 Immunostain, Technical Component Only
Classification of lymphomas
PRSSZ - Overview: PRSS1 Gene, Full Gene Analysis, Varies
Confirmation of suspected clinical diagnosis of hereditary pancreatitis (HP) in patients with chronic pancreatitis Identification of familial PRSSI mutation to allow for predictive and diagnostic testing in family members
RSBV - Overview: Rare Subepithelial Autoimmune Blistering Disease Variants, Serum
Aiding in the diagnosis of rare subepithelial autoimmune blistering diseases, including anti-laminin 332 pemphigoid, anti-p200 pemphigoid, epidermolysis bullosa acquisita, and systemic bullous lupus erythematosus
CHAGS - Overview: Trypanosoma cruzi Total Antibody, Enzyme-Linked Immunosorbent Assay, Serum
Diagnosis of chronic Trypanosoma cruzi infection (Chagas disease)
CUS1 - Overview: Copper, Serum
Diagnosis of: -Wilson disease -Primary biliary cholangitis -Primary sclerosing cholangitis
HG34W - Overview: Histone 3.3 G34W (H3F3A G34W) Immunostain, Technical Component Only
Aiding in the diagnosis of giant cell tumor of bone
HMHA - Overview: Heavy Metals, Hair
Detection of nonacute arsenic, mercury, and lead exposure using hair specimens
IGM - Overview: Immunoglobulin M (IgM), Serum
Detecting or monitoring of IgM monoclonal gammopathies and IgM-related immune deficiencies
IGAS - Overview: IgA Subclasses, Serum
Investigation of immune deficiency due to IgA2 deficiency Evaluating patients with anaphylactic transfusion reactions
LGBBS - Overview: Globotriaosylsphingosine, Blood Spot
Screening of patients with Fabry disease using dried blood spots when a serum specimen is not available This test should not be used for newborn screening followup.
ESTS - Overview: Estradiol, Rapid, Immunoassay, Serum
Rapid assessment of ovarian status, including follicle development, for assisted reproduction protocols (eg, in vitro fertilization) Establishing time of ovulation and optimal time for conception
GAL3 - Overview: Galectin-3, Serum
Aiding in the prognosis for patients diagnosed with heart failure Risk stratification of patients with heart failure An early indication of treatment failure and as a therapeutic target
LALB - Overview: Lysosomal Acid Lipase, Blood
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
IGG - Overview: Immunoglobulin G (IgG), Serum
Detecting or monitoring of IgG monoclonal gammopathies and immune deficiencies
MTDNU - Overview: Methadone Confirmation, Random, Urine
Monitoring for compliance of methadone treatment for analgesia or drug rehabilitation Assessing compliance with rehabilitation programs by urine measurement of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
BCGBM - Overview: Immunoglobulin Gene Rearrangement, PCR, Bone Marrow
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using bone marrow specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...
LRBA - Overview: Lipopolysaccharide-Responsive Beige-Like Anchor Protein (LRBA) Deficiency, Blood
Aiding in the diagnosis of lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency This test is not useful for identifying a carrier status for LRBA deficiency.
FUCW - Overview: Alpha-Fucosidase, Leukocytes
Detection of fucosidosis This test is not useful for establishing carrier status for fucosidosis.
ALU - Overview: Aluminum, 24 Hour, Urine
Monitoring aluminum exposure Preferred matrix for assessment of exposure in patients with normal kidney function since rapidly filtered by kidneys Monitoring metallic prosthetic implant wear This test is not an acceptable substitute for...
ALUCR - Overview: Aluminum/Creatinine Ratio, Random, Urine
Monitoring aluminum exposure when a 24-hour urine cannot be collected Monitoring metallic prosthetic implant wear when a 24-hour urine cannot be collected This test is not an acceptable substitute for serum aluminum measurements and is...
ALAUR - Overview: Aminolevulinic Acid, Urine
Assisting in the differential diagnosis of the acute hepatic porphyrias
SPAS - Overview: Arsenic Speciation, Random, Urine
Diagnosing arsenic intoxication using random urine specimens
SPASU - Overview: Arsenic Speciation, 24 Hour, Urine
Diagnosing arsenic intoxication using 24-hour urine specimens
A124 - Overview: Alpha-1-Microglobulin, 24 Hour, Urine
Assessment of renal tubular injury or dysfunction using 24-hour urine collections Screening for tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction(2)
ACTH - Overview: Adrenocorticotropic Hormone, Plasma
Determining the cause of hypercortisolism and hypocortisolism
APOLB - Overview: Apolipoprotein B, Serum
Assessment of cardiovascular risk Follow-up studies in individuals with basic lipid measures inconsistent with risk factors or clinical presentation Definitive studies of cardiac risk factors in individuals with significant family...
AFPA - Overview: Alpha-Fetoprotein, Amniotic Fluid
Screening for open neural tube defects or other fetal abnormalities Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing
BUPR - Overview: Buprenorphine Screen with Reflex, Random, Urine
Screening and confirmation for drug abuse or use of buprenorphine
Mucopolysaccharidosis type I (MPS I) is a rare genetic disorder that typically presents with progressive multisystem involvement in early childhood. This condition results from the deficiency of the enzyme...
webinar on implementation of high-sensitivity troponin I assay - Insights
Cardiovascular Diseases, will be presenting a webinar on the implementation of a high-sensitivity troponin I assay. The webinar will be held February 13 from 1:00-2:00 p.m. eastern....
Should I Stay or Should I Go? - Insights
In this episode of “Lab Medicine Rounds,” host Justin Kreuter, M.D., and Rondell Graham, M.B.B.S., delve into the critical decisions involved in contemplating a role on the staff at the institution where you receive your training.
often oversimplified & misunderstood technology--Part I
In the last decade, genetic testing has evolved from single-gene Sanger based assays to much more complex next-generation sequencing (NGS) based assays.
inform novel treatments for kidney stones - Part I - Insights
A collaborative study between Mayo Clinic and the University of Illinois debunked the previous consensus about how kidney stones grow.