ADALP - Overview: Adalimumab Quantitative with Antibody, Serum

Therapeutic drug monitoring of adalimumab concentration and antibody levels

FACT - Overview: Filamentous-Actin (F-actin) Antibody, IgG, Serum

Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes This test may also be useful for confirming positivity for smooth muscle antibodies.

AADAM - Overview: ADAMTS13 Profile Interpretation

Technical interpretation of a profile to assist with the diagnosis of congenital, immune, or acquired thrombotic thrombocytopenic purpura including inhibitor studies

MAGES - Overview: Myelin-Associated Glycoprotein Autoantibodies, IgM, Serum

Evaluating peripheral neuropathy Evaluating paraproteinemic neuropathy

VORI - Overview: Voriconazole, Serum

Monitoring trough levels of voriconazole is suggested for: -Individuals with reduced liver function -Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function -Patients taking other medications that...

ANST - Overview: Androstenedione, Serum

Diagnosis and differential diagnosis of hyperandrogenism, in conjunction with measurements of other sex steroids Diagnosis of congenital adrenal hyperplasia (CAH), in conjunction with measurement of other androgenic precursors,...

THSIF - Overview: Thrombospondin Type 1 Domain Containing 7A (THSD7A), Immunofluorescence

Diagnosis of thrombospondin type 1 domain-containing 7A (THSD7A)-associated membranous nephropathy

PBORB - Overview: Lyme Disease, Molecular Detection, PCR, Blood

Supporting the diagnosis of Lyme disease in conjunction with serologic testing This test should not be used to screen asymptomatic patients.

LNBAI - Overview: Lyme Central Nervous System Infection IgG, Antibody Index, Spinal Fluid

Providing antibody index information to aid in the diagnosis of neuroinvasive Lyme disease or neuroborreliosis due to Borrelia species associated with Lyme disease (eg, Borrelia burgdorferi, Borrelia garinii, Borrelia afzelli)

FCZAC - Overview: Certolizumab and Anti-Certolizumab Antibody, DoseASSURE CTZ

Provides certolizumab drug concentration and anti-certolizumab antibodies in order to optimize treatment and facilitate clinical decision-making. This assay may be helpful in any patient on certolizumab therapy for Crohn's disease,...

ROMA2 - Overview: Risk Score, if Postmenopausal, Serum

Calculating risk assessment for finding an ovarian malignancy during surgery in postmenopausal women who present with an adnexal mass

ROMA1 - Overview: Risk Score, if Premenopausal, Serum

Calculating risk assessment for finding an ovarian malignancy during surgery in premenopausal women who present with an adnexal mass

AST - Overview: Aspartate Aminotransferase (AST) (GOT), Serum

Diagnosing and monitoring liver disease, particularly diseases resulting in a destruction of hepatocytes

PERAM - Overview: Perampanel, Serum

Monitoring serum concentration of perampanel, in specific clinical conditions (ie, severe kidney impairment, mild to moderate hepatic impairment, and end-stage kidney disease) Assessing compliance Assessing potential toxicity

RNAUR - Overview: Sodium, Random, Urine

Assessing acid-base balance, water balance, water intoxication, and dehydration

SAT - Overview: Percent Saturation

Calculation of percent saturation

CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma

Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing

MONOF - Overview: Monocyte Repartition by CD14/CD16, Blood

Aiding in the diagnosis and monitoring of chronic myelomonocytic leukemia

SP142 - Overview: Programmed Death-Ligand 1 (PD-L1) (SP142), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP142)

22C3 - Overview: Programmed Death-Ligand 1 (PD-L1) (22C3), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone 22C3)

HPYL - Overview: Helicobacter pylori (H pylori) Immunostain, Technical Component Only

Aiding in the identification of Helicobacter pylori infection

CSPCF - Overview: Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow

Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders Sorting plasma cells for fluorescence in situ hybridization analysis

IMMAU - Overview: Inborn Errors of Immunity with Immune Dysregulation and Autoimmunity Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity (IEI) associated with immune dysregulation or autoimmunity Establishing a diagnosis of an IEI, allowing...

RETZZ - Overview: Multiple Endocrine Neoplasia Type 2 Syndrome, RET, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of a multiple endocrine neoplasia type 2 (MEN2) or Hirschsprung disease (HSCR) Establishing a diagnosis of MEN2 or HSCR allowing for targeted cancer surveillance based on...

LEVE - Overview: Levetiracetam, Serum

Monitoring serum concentration of levetiracetam, particularly in patients with kidney disease Assessing compliance with levetiracetam therapy Assessing potential toxicity of levetiracetam

CLDL1 - Overview: Cholesterol, Low-Density Lipoprotein (LDL), Calculated, Serum

Calculation of low-density lipoprotein cholesterol using total cholesterol, non-high-density lipoprotein (HDL) cholesterol, HDL cholesterol, and triglyceride concentrations Managing atherosclerotic cardiovascular disease risk

CD43 - Overview: CD43 Immunostain, Technical Component Only

Identification of T lymphocytes, monocytes, macrophages, granulocytes, plasma cells, and a subset of B lymphocytes

IGAI - Overview: IgA Immunostain, Technical Component Only

Aiding in the classification of lymphomas and multiple myeloma

HMB45 - Overview: HMB45 Immunostain, Technical Component Only

Identification of activated and neoplastic melanocytes

MNRCU - Overview: Manganese/Creatinine Ratio, Random, Urine

Monitoring manganese exposure using random urine specimens Nutritional monitoring Clinical trials

MYOD1 - Overview: Myogenic Differentiation Antigen 1 (MYOD1) Immunostain, Technical Component Only

Marker of skeletal muscle differentiation

MNCU - Overview: Manganese/Creatinine Ratio, Urine

Measurement of manganese as a part of a profile Monitoring manganese exposure Nutritional monitoring Clinical trials

PRAME - Overview: PRAME Immunostain, Technical Component Only

Differentiation between melanoma and benign nevi.

TICU - Overview: Titanium/Creatinine Ratio, Urine

Measurement of titanium concentration as part of a profile to assess exposure and elimination of titanium

ALKLC - Overview: Anaplastic Lymphoma Kinase for Lung Cancer, Immunohistochemistry

Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor, anaplastic large-cell lymphoma, and for targeted therapy of lung adenocarcinoma

BRACH - Overview: Brachyury Immunostain, Technical Component Only

Aiding in the identification of chordomas

DESMN - Overview: Desmin Immunostain, Technical Component Only

Identification of striated and smooth muscle cells and tumors derived from this cell type

DESG3 - Overview: Desmoglein 3 (DSG3) Immunostain, Technical Component Only

Classification of squamous cell carcinomas

CO4D - Overview: Complement 4d Immunostain, Technical Component Only

Identification of antibody-mediated transplant rejection

CA - Overview: Calcium, Total, Serum

Diagnosis and monitoring of a wide range of disorders including diseases of bone, kidney, parathyroid gland, or gastrointestinal tract

CD79 - Overview: CD79a Immunostain, Technical Component Only

Phenotyping leukemias and lymphomas

CD14I - Overview: CD14 Immunostain, Technical Component Only

Marker of histiocytic and monocytic lineage and follicular dendritic cells

CD1A - Overview: CD1a Immunostain, Technical Component Only

Marker of Langerhans cells and immature T cells

CALPN - Overview: Calponin Immunostain, Technical Component Only

Marker for myoepithelium when differentiating ductal carcinomas in situ from infiltrating breast carcinoma Characterization of tumors of smooth muscle or myoepithelial lineage

CD20I - Overview: CD20 Immunostain, Technical Component Only

Classification of lymphomas

CALCI - Overview: Calcitonin (CALCI) Immunostain, Technical Component Only

Aids in the identification of C cells of thyroid, medullary thyroid carcinomas, many atypical laryngeal carcinoids, and other neuroendocrine tumors

C4 - Overview: Complement C4, Serum

Investigating an undetectable total complement Confirming hereditary angioedema (with low C1 inhibitor) Assessing disease activity in systemic lupus erythematosus, proliferative glomerulonephritis, rheumatoid arthritis, and autoimmune...

CD3I - Overview: CD3 Immunostain, Technical Component Only

Demonstrating T-cell lineage

CD4I - Overview: CD4 Immunostain, Technical Component Only

Identification of T helper cells, histiocytes, and monocytes

CD38 - Overview: CD38 Immunostain, Technical Component Only

Classification of lymphoproliferative and plasma cell proliferative disorders