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CPT codes and LOINC update: May 2023 - Insights

This page includes updates posted to Mayo Clinic Labs during the month of May.

Ceramide testing helps shape individualized heart health treatment plan: Mark Kocak - Insights

An avid runner and fitness buff, Mark Kocak didn’t think he needed medication for his high cholesterol and hypertension. After coming to Mayo Clinic for ceramide testing, Mark knew exercise alone would not be enough to him on a path toward...

Pathways Case Studies: October 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties Breast Pathology, Gynecological...

Laboratory Utilization Management: Tick-Borne Disease Testing - Insights

In this month's "Hot Topic," Elitza Theel, Ph.D., will be discussing laboratory utilization management, specifically for diagnostic testing for tick-borne diseases.

Syndromic Testing for Infectious Diseases: Respiratory Infections - Insights

In this month's "Hot Topic," Matthew Binnicker, Ph.D., discusses the use of multiplex panels for the diagnosis of respiratory infections and focuses on the clinical utility of these tests in the setting of upper respiratory tract...

October 2023 - Clinical Microbiology - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Microbiology.

August 2023 - Lab Genetics & Genomics - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Laboratory Genetics and Genomics.

Neurology - Insights

A collaboration with Mayo Clinic BioPharma Diagnostics includes access to the neurologic disease testing capabilities of Mayo Clinic Laboratories. Our highly specialized neurology testing menu features more than 400 neurologist-backed...

New tests launched in December - Insights

December 2021, Mayo Clinic Laboratories announced thirty new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Clinical microbiology at Mayo Clinic: A look back and ahead - Insights

The field of clinical microbiology has a long and distinguished history at Mayo Clinic. Since the early 1900s, the clinical microbiology team has played important and leading roles in advancing testing and patient care.

A web of care, close to home: Support on the cancer journey - Insights

Dr. Dollahite received world-class cancer treatment from a web of health care organizations, including Mayo Clinic in Rochester, Minnesota. Yet she never left New York; most of her treatment occurred in Ithaca. What made that possible was...

FISH testing helps detect unseen cancer cells: Shannon Camlek - Insights

On the brink of losing her battle with acute myeloid leukemia, Shannon Camlek arrived at Mayo Clinic as a last hope. Her chances didn’t look good, but with the help of specialized genetic testing, particularly FISH (fluorescence in situ...

The birth of Mayo Clinic Laboratories: From tiny operation to international mainstay - Insights

In 1971, the Regional Laboratory, later to become Mayo Clinic Laboratories, was founded. For the first time in Mayo Clinic’s history, the institution would support the community practice of pathology for outside patients in the region and...

Heartbeats of gratitude: Scott Olson - Insights

In a quiet suburb outside of Minneapolis, Minnesota, an ordinary Saturday took a sudden and alarming turn for Scott Olson when he began experiencing symptoms of ventricular tachycardia. Central to the care and treatment he'd receive at Mayo...

Pathways Case Studies: November 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for November include the following sub-specialties: Cardiovascular Pathology,...

Heparin Induced Thrombocytopenia (HIT) and the Role of Serotonin Release Assay (SRA) - Insights

In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia (HIT), approach diagnosis, and the role of the functional serotonin release assay (SRA).

Cutting-Edge Bacterial Testing for the Diagnosis of Patient Infections and Outbreak Mitigation - Insights

Mayo Clinic Laboratories is one of the few laboratories in the country to offer two special sequencing-based tests for bacteria in its catalog. The first test is designed to help protect patients by investigating potential outbreaks of a...

Comprehensive testing helps diagnose and manage rare genetic disorder: Lauri Sieben - Insights

Multiple doctors and multiple examinations could not figure out why Lauri Sieben had spent much of her life “never feeling quite right” physically. Fortunately for Lauri, that changed after her daughter Christy began working as a genetic...

A "sandbox" for innovation: The Advanced Diagnostics Laboratory - Insights

Mayo Clinic’s Advanced Diagnostics Laboratory (ADL) is a visionary space designed to foster innovation. The ADL has a direct impact on patient lives, bringing promising tests and services to patients at Mayo and around the world.

Pathways Case Studies: April 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for April include the following sub-specialties: Gynecological Pathology, Pulmonary...

Phlebotomy Top Gun: Safe Handling of Laboratory Specimens During the COVID-19 Pandemic - Insights

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., addresses the safe handling of laboratory specimens submitted during the COVID-19 pandemic through his yearly Phlebotomy Top Gun presentation based on the previous year’s Phlebotomy...

Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights

In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections.

New tests launched in January - Insights

In January 2023, Mayo Clinic Laboratories announced fifty-nine new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Defying all odds and exploring a remarkable journey beyond diagnosis: Mike Knudson - Insights

In August of 2021, 28-year-old Mike Knudson, a Twin Cities resident known for his vibrant and active lifestyle, set out on what he anticipated to be an adventurous hiking vacation to the picturesque Glacier National Park in Montana. Little...

Dengue Virus: A Diagnostic Testing Update - Insights

In this month’s “Hot Topic,” Elitza Theel, Ph.D., talks about Mayo Clinic Laboratories’ serologic and molecular testing for the identification of infection with dengue virus. Dengue virus poses a significant public health threat worldwide....

Weeding Through the Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights

In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC) to creatinine ratio along with a...

Surprises in Coagulation Testing - Insights

In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.

Alzheimer's Disease CSF Biomarkers - Insights

In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.

PD-L1 Testing by Immunohistochemistry - Insights

In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.

Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry in Clinical Microbiology - Insights

In this month’s “Hot Topic,” Robin Patel, M.D., discusses how matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry works for bacterial identification, including the strengths and limitations of this...

Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights

In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...

New tests launched in November - Insights

In November 2021, Mayo Clinic Laboratories announced thirty four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Behind the scenes in neural antibody testing - Insights

In this month’s “Hot Topic,” John Mills, Ph.D., explains the central role of tissue immunofluorescence in the identification of neural antibodies and discusses the benefits of an integrated laboratory approach to the development and...

Selecting Pathology Specimens for Solid Tumors Next-Generation Sequencing - Insights

In this month’s “Hot Topic,” Sounak Gupta, M.B.B.S., Ph.D., discusses selecting tissues and other tissue considerations for molecular testing. He also reviews tissue metrics and requirements, which differ based on test platforms. It is...

Autoimmune Encephalitis Misdiagnosis - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B. Ch., discusses the important issue of autoimmune encephalitis misdiagnosis and identifies red flags that be useful in clinical practice to suggest alternative diagnoses and highlight...

Testing for Antibodies to SS-A/Ro in Autoimmune Diseases - Insights

In this month’s “Hot Topic,” Anne Tebo, Ph.D., discusses recent updates in the testing for anti-SS-A/Ro antibodies in systemic autoimmune rheumatic diseases.

Pathways Case Studies: March 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cytopathology,...

Lyme Disease Part 1: The Common Culprits Worldwide-Borrelia burgdorferi, Borrelia garinii, Borrelia afzelii - Insights

In this “Hot Topic,” Elitza Theel, Ph.D., discusses how common cases of presumed Lyme disease go unreported each year and discusses scenarios in which testing for Lyme disease is indicated and reviews both recommended and inappropriate...

Understanding Membranoproliferative Glomerulonephritis, Including C3 Glomerulopathy: Part 2 - Insights

Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury. Based on the etiology of MPGN, Drs. Sethi and Fervenza proposed a new histologic classification of MPGN into Ig/IC-mediated MPGN and complement-mediated...

New tests launched in December - Insights

In December 2022, Mayo Clinic Laboratories announced seventy-eight new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Osmotic fragility testing - Insights

In this month’s “Hot Topic,” James Hoyer, M.D., discusses the importance of using a control tube during osmotic fragility testing.

Pleural Mesothelioma - Insights

In this month's "Hot Topic," Anja Roden, M.D., a thoracic pathologist at Mayo Clinic, gives an update on the 2021 World Health Organization (WHO) classification and ancillary testing of pleural mesothelioma.

Antifungal Drug Susceptibility Testing of Yeast: A Primer for Beginners - Insights

In this month’s “Hot Topic,” Nancy Wengenack, Ph.D., discusses susceptibility testing of yeast for those who are considering performing it in their laboratory, perhaps for the first time, or for those who choose to send their yeast isolates...

Understanding Membranoproliferative Glomerulonephritis, Including C3 Glomerulopathy: Part 1 - Insights

Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury. Based on the etiology of MPGN, Drs. Sethi and Fervenza proposed a new histologic classification of MPGN into Ig/IC-mediated MPGN and complement-mediated...

Pediatric neuro-oncology informative cases - Insights

Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...

Pathways Case Studies: December 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Cardiovascular Pathology and...

Pathways Case Studies: December 2022 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Bone and Soft Tissue Pathology,...

Test Classification Updates - Mayo Clinic Laboratories

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MAYO AZ out of state testing approval updated.pdf

Out of State Testing 899 North Capitol Street NE | 2nd Fl, Washington, DC 20002 | P 202-724-8800 | F 202-724-8677 | dchealth.dc.gov Date: August 11, 2023 RE: Out of State Testing Approval HFD-OS35 MAYO CLINIC MOLECULAR DIAGNOSTICS AZ is...

CPT Code Updates - Mayo Clinic Laboratories

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