Detecting drug abuse involving barbiturates such as amobarbital,
Gas Chromatography-Mass Spectrometry (GC-MS) Confirmation with Quantitation
Amobarbital (Amytal)
Amytal (Amobarbital)
Barbita (Phenobarbital)
Barbiturates
Barbs
Luminal (Phenobarbital)
Nembutal (Pentobarbital)
Pentobarbital (Nembutal)
Phenobarbital
Secobarbital (Seconal)
Seconal (Secobarbital)
Solfoton (Phenobarbital)
Butalbital (Fiorinal)
Urine
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order BARBX / Barbiturates Confirmation, Chain of Custody, Random, Urine.
2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.
3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. No specimen substitutions.
2. STATS are not accepted for this test.
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
5 mL
Gross hemolysis | OK |
Gross icterus | OK |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 14 days | |
Frozen | 14 days | ||
Ambient | 72 hours |
Detecting drug abuse involving barbiturates such as amobarbital,
Barbiturates represent a class of drugs that were originally introduced
Negative
Cutoff concentrations:
BUTALBITAL BY GC-MS
<100 ng/mL
AMOBARBITAL BY GC-MS
<100 ng/mL
PENTOBARBITAL BY GC-MS
<100 ng/mL
SECOBARBITAL BY GC-MS
<100 ng/mL
PHENOBARBITAL BY GC-MS
<100 ng/mL
The presence of a barbiturate in urine indicates use of one of these drugs.
Most of the barbiturates are fast acting; their presence indicates
Phenobarbital, commonly used to control epilepsy, has a very long
No significant cautionary statements.
1. Disposition of Toxic Drugs and Chemicals in Man. 10th edition. Edited by RC Baselt. Foster City, CA: Biomedical Publications, 2014
2. Langman LJ et al: Clinical Toxicology. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Edited by N Rifai, AR Horvath, CT Wittwer. Sixth edition. Elsevier, 2018, pp 832-887
Gas chromatography-mass spectrometry confirmation with quantitation.(Porter WH, Moyer TP: Clinical toxicology. In Tietz Textbook of Clinical Chemistry. Second edition. Edited by CA Burtis, ER Ashwood. WB Saunders Company, 1994, pp 1162-1167)
Tuesday, Thursday, Sunday
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.
80345
G0480 (if appropriate)
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
BARBU | Barbiturates Confirmation, U | 53746-4 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
21442 | Butalbital-by GC/MS | 16237-0 |
20642 | Amobarbital-by GC/MS | 16239-6 |
20643 | Pentobarbital-by GC/MS | 16240-4 |
20644 | Secobarbital-by GC/MS | 16238-8 |
20645 | Phenobarbital-by GC/MS | 16241-2 |
20651 | Barbiturates Interpretation | 69050-3 |
20647 | Chain of Custody | 77202-0 |