Test Catalog

Test ID: Q10    
Coenzyme Q10, Reduced and Total, Plasma

Specimen Type Describes the specimen type validated for testing

Plasma Heparin

Advisory Information

This test provides both reduced and total coenzyme Q10. For assessment of total only, order TQ10 / Coenzyme Q10, Total, Plasma.


The level of oxidized Q10 was affected in specimens with even slight amounts of hemolysis; however, the total Q10 level remains constant. Hemolyzed specimens can be analyzed for total Q10 using TQ10 / Coenzyme Q10, Total, Plasma.


The most reliable test for the diagnosis of primary defects in ubiquinone (CoQ10) biosynthesis is direct measurement of CoQ10 in muscle.

Shipping Instructions

If possible, do not send other tests ordered on same vial of plasma. In doing so, the other tests may have increased turnaround time due to the strict frozen criteria of this assay.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Patient Preparation: Fasting (8 hours)

Collection Container/Tube: Green top (lithium or sodium heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Immediately after collection, place specimen on wet ice. Maintain on wet ice and process within 3 hours of collection.

2. Centrifuge, separate plasma from cells, and immediately freeze specimen.


If not ordering electronically, complete, print, and send an Inborn Errors of Metabolism Test Request (T798) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

0.3 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Plasma HeparinFrozen (preferred)14 days
 Refrigerated 8 hours