Test Catalog

Test ID: BHISC    
Bone Histomorphometry, Gross Microscopic Exam

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Hematoxylin and eosin-stained slides are sent to pathology for review. Iron staining or aluminum staining may be performed at an additional charge.

Specimen Type Describes the specimen type validated for testing


Shipping Instructions

It is preferred that the specimen is shipped in 70% ethanol because it preserves the tetracycline label in the bone.

Necessary Information

Bone Histomorphometry: Patient Information (T352) in Special Instructions must be completed and sent with the specimen. The laboratory requires this information in order to perform testing.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing


-Metal Free Specimen Vial (T173)

-Bone Histomorphometry Specimen Preparation (T579)

Specimen Type: Bone

Preferred: Anterior iliac crest

Container/Tube: Metal-free container (T173)

Specimen Volume: Entire specimen

Collection Instructions:

1. Fix specimen in 70% ethanol.

2. Quantitation of bone turnover requires 2 time-spaced tetracycline labels.

3. The use of metal-free containers is required to avoid aluminum or iron contamination.

Additional Information:

1. Consultation with a Mayo Clinic Laboratories pathologist or endocrinologist/nephrologist is recommended for first-time users of this service. Written instructions are available upon request.

2. For more information, see Bone Histomorphometry Specimen Preparation (T579) in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test


Bone Histomorphometry: Patient Information (T352) in Special Instructions

Bone Histomorphometry Specimen Preparation (T579) in Special Instructions

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Bone Fixatives other than 70% alcohol or decalcified bone

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
VariesAmbient (preferred)