Test Catalog

Test ID: MRDMM    
Multiple Myeloma Minimal Residual Disease by Flow, Bone Marrow

Specimen Type Describes the specimen type validated for testing

Bone Marrow

Advisory Information

MRDMM should be ordered when monitoring Multiple Myeloma patients after treatment. This test should not be ordered on known relapsing patients or at diagnosis, see PCPRO / Plasma Cell DNA Content and Proliferation, Bone Marrow or MSMRT / Mayo Algorithmic Approach for Stratification of Myeloma and Risk-Adapted Therapy Report if indicated for these situations.

Shipping Instructions

It is recommended that specimens arrive within 48 hours of draw.  Draw and package specimen as close to shipping time as possible. 

Necessary Information

1. Include patient's disease state (untreated, treated, monoclonal gammopathy of undetermined significance, stable).

2. Indicate if patient is on anti-CD38 therapy.

3. Provide Immunofix information if available.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Specimen Type: Redirected bone marrow


Preferred: Yellow top (ACD)

Acceptable: Lavender top (EDTA)

Specimen Volume: 4 mL


If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen. 

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

2 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Bone MarrowAmbient (preferred)72 hours
 Refrigerated 72 hours