Test Catalog

Test ID: CHIMU    
Chimerism Transplant No Cell Sort, Varies

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial Chimerism Testing:

Complete chimerism analysis requires 3 specimens. These specimens should be submitted when collected. An interpretive report will be provided once all specimens are received.


-CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies

-CHIDB / Chimerism-Donor, Varies

-CHIMU / Chimerism Transplant No Cell Sort, Varies


See Chimerism-Recipient Germline Testing Algorithm in Special Instructions.

Specimen Type Describes the specimen type validated for testing


Ordering Guidance

This test is for the post-bone marrow transplant evaluation of the donor specimen. For post-bone marrow transplant testing to determine the relative amounts of donor and recipient cells, see CHIMS / Chimerism Transplant Sorted Cells, Varies.

Additional Testing Requirements

Complete chimerism analysis also requires submission of CHRGB / Chimerism-Recipient Germline (Pretransplant), Varies and CHIDB / Chimerism-Donor, Varies specimens. These tests must be ordered on both the pre and donor specimens under separate order numbers. While the 3 specimens do not need to be submitted at the same time, the CHRGB and CHIDB specimens must be received before this test can be performed.

Shipping Instructions

Specimen must arrive within 7 days (168 hours) of collection. Collect and package specimen as close to shipping time as possible.

Necessary Information

The following information is required:

1. Pertinent clinical history

2. Specimen source

3. Donor identifier and donor date of birth

4. Donor date of collection

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Submit only 1 of the following specimens:


Specimen Type: Blood


Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 4 mL

Collection Instructions:

1. Only 1 tube is required.

2. Invert several times to mix blood.

3. Send specimen in original tube. Do not aliquot.

4. Label specimen as blood.


Specimen Type: Bone marrow


Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube. Do not aliquot.

3. Label specimen as bone marrow.

Special Instructions Library of PDFs including pertinent information and forms related to the test


1. Chimerism Analysis Information Sheet (T594) in Special Instructions.

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Blood: 3 mL
Bone Marrow: 2 mL
Lesser volumes may be acceptable, depending on white cell count.
Call 800-533-1710 or 507-266-5700 with questions.

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Moderately to severely clotted Reject

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
VariesAmbient (preferred)7 daysPURPLE OR PINK TOP/EDTA
 Refrigerated 7 daysPURPLE OR PINK TOP/EDTA