Test Catalog

Test ID: HPFRP    
Helicobacter pylori with Clarithromycin Resistance Prediction, Molecular Detection, PCR, Feces

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Helicobacter pylori Diagnostic Algorithm in Special Instructions.

Specimen Type Describes the specimen type validated for testing


Advisory Information

Confirmation of eradication testing should not be ordered until 4 or more weeks after cessation of treatment.

Necessary Information

Specimen source is required.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

The high sensitivity of amplification by polymerase chain reaction (PCR) requires the specimen to be processed in an environment in which contamination of the specimen by Helicobacter pylori DNA is unlikely.


Patient Preparation: Proton pump inhibitors, histamine H2preceptor antagonists and other antacids, as well as antibiotics and bismuth compounds, should be discontinued at least 2 weeks prior to testing.

Supplies: C and S Vial (T058)

Specimen Type: Preserved feces

Submission Container/Tube: Commercially available transport system specific for recovery of enteric pathogens from fecal specimens (15 mL of nonnutritive transport medium containing phenol red as a pH indicator, either Cary-Blair or Para-Pak C and S)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect fresh fecal specimen and submit 1 gram or 5 mL in container with transport medium.

2. Place feces in preservative within 2 hours of collection.

3. Place vial in a sealed plastic bag.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Fecal swab
ESwab transport medium Fecal ESwab transport medium
Feces in gel transport medium
ECOFIX preservative formalin
PVA fixative

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
FecalRefrigerated (preferred)7 days
 Frozen 7 days