Test Catalog

Test ID: CMAH    
Chromosomal Microarray, Hematologic Disorders, Varies

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

DNA extraction is always performed on the specimen prior to hybridization to the microarray. An unstimulated cell culture will be set up on all specimens with adequate volume and held pending additional testing. If additional testing is requested, such as karyotype analysis or FISH, it will be performed at an additional charge.


This test is not appropriate for detecting constitutional/congenital copy number changes or regions of excessive homozygosity. If this test is ordered with a reason for referral indicating a constitutional/congenital disorder, the test will be cancelled and CMACB / Chromosomal Microarray, Congenital, Blood will be performed as the appropriate test.


The following algorithms are available in Special Instructions:

-Aggressive B-cell Lymphoma Diagnostic Algorithm in Special Instructions

-B-Lymphoblastic Leukemia/Lymphoma Algorithm

Specimen Type Describes the specimen type validated for testing


Necessary Information

1. A reason for referral must be provided for testing to be performed.

2. A pathology report should accompany the specimen. If this information is not available at the time of order, submit as soon as possible for appropriateness of testing and to aid in interpretation of results.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Provide a reason for referral with each specimen. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed.


Submit only 1 of the following specimens:


Specimen Type: Bone marrow
Container/Tube: Green top (sodium heparin)
Specimen Volume: 1-2 mL
Collection Instructions:
1. Invert several times to mix bone marrow.
2. If sodium heparin is not available, EDTA is acceptable.


Specimen Type: Whole blood
Container/Tube: Green top (sodium heparin)
Specimen Volume: 7-10 mL
Collection Instructions:
1. Invert several times to mix blood.
2. If sodium heparin is not available, EDTA is acceptable.

Special Instructions Library of PDFs including pertinent information and forms related to the test


If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen. 

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Blood: 2 mL
Bone Marrow: 1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
VariesAmbient (preferred)