Test Catalog

Test ID: T790M    
Cell-Free DNA EGFR T790M Mutation Analysis, Blood

Specimen Type Describes the specimen type validated for testing

Whole blood

Ordering Guidance

This test is not a prenatal screening test. To evaluate for the presence of common fetal chromosome abnormalities using cell-free DNA, see NIPS / Cell-Free DNA Prenatal Screen.


This test detects only the T790M mutation in the EGFR gene. It does not detect other EGFR gene mutations in exons 18 through 21. For that purpose, order EGFRD / Cell-Free DNA EGFR Exon 18, 19, 20, 21, Mutation Analysis, Blood.


This test provides rapid detection of the EGFR T790M mutation in peripheral blood from non-small cell lung cancer patients as an alternative for EGFR analysis of tissue. For tissue testing, order EGFRT / EGFR Gene, Mutation Analysis, 29 Mutation Panel, Tumor.

Shipping Instructions

1. Samples should be transported at ambient temperature or refrigerated (4 degrees C)

2. Samples are viable for 7 days in the Streck Black/Tan Top Tube Kit (T715)

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Streck Black/Tan Top Tube Kit (T-715)

Specimen Volume: Two 10-mL Streck Cell-Free DNA blood collection tubes

Additional Information:

1. Only blood collected in Streck Cell-Free DNA BCT tubes will be accepted for analysis. Whole blood will be processed to produce platelet poor plasma before cfDNA isolation.

2. Samples should be transported at room temperature or refrigerated (4 degrees C)

3. Samples are viable for 7 days in the Streck Cell-Free DNA BCT tube.


If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

One 10 mL Streck tube

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

No specimen collected in the proper container will be rejected.

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Whole bloodAmbient (preferred)7 daysStreck Black/Tan top
 Refrigerated 7 daysStreck Black/Tan top