Test Catalog

Test ID: FMSS2    
Maternal Serum Screening, Integrated, Specimen #2, Alpha Fetoprotein, Hcg, Estriol, and Inhibin A

Method Description Describes how the test is performed and provides a method-specific reference

PAPP-A is pregnancy-associated plasma protein A and is a sequential immunoenzymatic assay that uses two monoclonal antibodies and external calibrators.


AFP and hCG are both measured using a non-competitive immunoassay that uses one antibody to capture the protein to a solid phase, another antibody to detect the protein, and external calibrators.


The estriol assay is a solid phase competitive immunoassay that uses an anti-estriol polyclonal antibody, labeled estriol, a solid phase antibody directed against the estriol antibody, and external calibrators.


Inhibin-A is measured using a non-competitive microtiter immunoassay that uses a detection antibody to subunit a, a capture antibody to inhibin subunit BA, and external calibrators.


Calculation of post-test risks uses a multivariate log Gaussian model. Risk estimates for DS and T18 are influenced strongly by maternal age.

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) Performed Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Sunday - Saturday

Report Available The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

2 to 8 days

Performing Laboratory Location Indicates the location of the laboratory that performs the test

ARUP Laboratories