Test Catalog

Test ID: HAIGM    
Hepatitis A IgM Antibody, Serum

Method Description Describes how the test is performed and provides a method-specific reference

The ARCHITECT HAVAB-M assay is a 2-step automated immunoassay designed for the qualitative detection of hepatitis A virus (HAV)-specific IgM antibody in human serum and plasma using chemiluminescent microparticle immunoassay (CMIA) method. Prediluted patient sample, assay diluent, and HAV-coated paramagnetic microparticles are combined first in a reaction well. Anti-HAV IgM present in the patient sample binds to the HAV-coated microparticles. After washing, acridinium-labeled antihuman IgM conjugate is added to bind to anti-HAV IgM. Following another wash cycle, pretrigger and trigger solutions are added to the reaction mixture. The resulting chemiluminescent reaction is measured as relative light units (RLUs). A direct relationship exists between the amount of anti-HAV IgM present in the patient sample and the RLUs detected by the ARCHITECT System optics. The presence or absence of anti-HAV IgM in the patient sample is determined by comparing the chemiluminescent signal in the reaction to the cutoff signal determined from an active ARCHITECT HAVAB-M calibration. Specimens with signal to cutoff (S/CO) values at or above 1.21 are considered positive for anti-HAV IgM. Specimens with S/CO values of 0.80 to below 1.21 are considered equivocal. Specimens with S/CO values of 0.80 are considered negative.(Package insert: Architect HAVAB-M; Abbott Laboratories, Abbott Park, IL; G6-5290/R05 B6L210; February 2016)

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday through Saturday; Varies

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Clinic Laboratories until the release of the test result

2 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

14 days

Performing Laboratory Location Indicates the location of the laboratory that performs the test