Test Id : FNTSM
Neurotransmitter Profile 3
Profile Information
A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test Id | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| F5MET | 5-Methyltetrahydrofolate | Yes, (order F5M) | Yes |
| FNTM | Neurotransmitter Metabolites/Amines | Yes, (order FNEU) | Yes |
| FFTHB | Tetrahydrobiopterin/Neopterin | Yes, (order FFTEN) | Yes |
Method Name
A short description of the method used to perform the test
High Performance Liquid Chromatography-Electrochemistry & Fluorescences
NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test
Aliases
Lists additional common names for a test, as an aid in searching
5-Methyltetrahydrofolate
Neurotransmitter Metabolites
Neurotransmitter Metabolites/Amines
Tetrahydrobiopterin/Neopterin
Specimen Type
Describes the specimen type validated for testing
CSF
Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing
Medical Neurogenetics collection kit (MCL Supply T657) required.
Each collection kit contains 5 microcentrifuge tubes.
COLLECTION PROTOCOL:
1) CSF should be collected from the first drop into the tubes in the numbered order. Fill each tube to the marked line with the required volumes.
Tube 1: 0.5 mL
Tube 2: 1.0 mL
Tube 3: 1.0 mL (contains antioxidants necessary to protect the same integrity)
Tube 4: 1.0 mL
Tube 5: 1.0 mL
-If samples not blood contaminated, the tubes should be placed on dry ice at bedside.
-If samples are blood contaminated, the tubes should immediately be centrifuged (prior to freezing) and the clear CSF transferred to new similarly labeled tubes, then frozen.
-Store samples at -80 until they can be shipped.
2) Complete Medical Neurogenetics, LLC request form, marking the following three tests: Neurotransmitter Metabolites, Tetrahydrobiopterin and 5-Methyltetrahydrofolate. Also include sample date and date of birth.
3) Label tubes with patient name and ID number, leaving the tube number viewable.
4) Place samples inside the specimen transport bag and the Medical Neurogenetics, LLC request form inside the pouch of the transport bag.
5) Ship samples frozen on dry ice.
Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected
| Specimens other than | CSF in special collection kit (MCL supply T657) |
| Anticoagulants other than | NA |
| Hemolysis | NA |
| Lipemia | NA |
| Icteric | NA |
Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| CSF | Frozen | CSF KIT | |
Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
5-Methyltetrahydrofolate
| Age (years) | 5MTHF (nmol/L) |
| 0-0.2 | 40-240 |
| 0.2-0.5 | 40-240 |
| 0.5-2.0 | 40-187 |
| 2.0-5.0 | 40-150 |
| 10-15 | 40-128 |
| Adults | 40-120 |
Neurotransmitter Metabolites/Amines
| Age (years) | 5HIAA (nmol/L) | HVA (nmol/L) | 3-O-MD (nmol/L) |
| 0-0.2 | 208-1159 | 337-1299 | <300 |
| 0.2-0.5 | 179-711 | 450-1132 | <300 |
| 0.5-2.0 | 129-520 | 294-1115 | <300 |
| 2.0-5.0 | 74-345 | 233-928 | <150 |
| 5.0-10 | 66-338 | 218-852 | <100 |
| 10-15 | 67-189 | 167-563 | <100 |
| Adults | 67-140 | 145-324 | <100 |
Neurotransmitter Metabolites/Amines
| Age (years) | 5HIAA (nmol/L) | HVA (nmol/L) | 3-O-MD (nmol/L) |
| 0-0.2 | 208-1159 | 337-1299 | <300 |
| 0.2-0.5 | 179-711 | 450-1132 | <300 |
| 0.5-2.0 | 129-520 | 294-1115 | <300 |
| 2.0-5.0 | 74-345 | 233-928 | <150 |
| 5.0-10 | 66-338 | 218-852 | <100 |
| 10-15 | 67-189 | 167-563 | <100 |
| Adults | 67-140 | 145-324 | <100 |
Tetrahydrobiopterin/Neopterin Profile
| Age (years) | BH4 (nmol/L | Neop (nmol/L) |
| 0-0.2 | 40-105 | 7-65 |
| 0.2-0.5 | 23-98 | 7-65 |
| 0.5-2.0 | 18-58 | 7-65 |
| 2.0-5.0 | 18-50 | 7-65 |
| 5.0-10 | 9-40 | 7-40 |
| 10-15 | 9-32 | 8-33 |
| Adults | 10-30 | 8-28 |
Note: If test results are inconsistent with the clinical
DISCLAIMER required by the FDA for high complexity clinical
PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.
Monday through Friday
Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.
Performing Laboratory Location
Indicates the location of the laboratory that performs the test
Fees :
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.
- Authorized users can sign in to Test Prices for detailed fee information.
- Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
- Prospective clients should contact their account representative. For assistance, contact Customer Service.
CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
CPT codes are provided by the performing laboratory.
CPT codes are provided by the performing laboratory.
82542 - 5-Methyltetrahydrofolate
82542 - Tetrahydrobiopterin/Neopterin
82542, 83497, 83150 - Neurotransmitter Metabolites/Amines
LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.
| Test Id | Test Order Name | Order LOINC Value |
|---|---|---|
| FNTSM | Neurotransmitter Profile 3 | Not Provided |
| Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
|---|---|---|
| Z1726 | 5-Methyltetrahydrofolate | 47547-5 |
| Z1730 | Neopterin | 34146-1 |
| Z1731 | Tetrahydrobiopterin | Not Provided |
| Z1732 | Interpretation | Not Provided |
| Z1727 | 5-Hydroxyindoleacetic acid | 47544-2 |
| Z1728 | Homovanillic acid | 40846-8 |
| Z1729 | 3-O-methyldopa | 34596-7 |