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Test ID: PYR    
Pyruvic Acid, Blood

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Useful For Suggests clinical disorders or settings where the test may be helpful

Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time to determine the lactate-to-pyruvate ratio

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

The lactate:pyruvate (L:P) ratio is considered a helpful (not diagnostic) tool in the evaluation of patients with possible disorders of mitochondrial metabolism, especially in patients with neurologic dysfunction and normal blood L:P ratios. Pyruvic acid levels alone have little clinical utility.

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Epilepsy: Unexplained Refractory and/or Familial Testing Algorithm in Special Instruction.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Spectrophotometry (SP)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Pyruvic Acid, B

Aliases Lists additional common names for a test, as an aid in searching

ETC
Mitochondrial Electron Transport Chain Defects
Mitochondrial Respiratory Chain Disorders
PC
PDH (Pyruvate Dehydrogenase) Deficiency
PDHC (Pyruvate Dehydrogenase Complex)
Pyruvate Carboxylase Deficiency
Pyruvate Decarboxylase Deficiency
Pyruvate Dehydrogenase (PDH) Deficiency
Pyruvate Dehydrogenase Complex (PDHC)
Pyruvate, Blood
Lactate to Pyruvate Ratio (LACS1 / Lactate, Plasma needs to be drawn at the same time, but has different specimen requirements)