Test Catalog

Test ID: HITIG    
Heparin-PF4 IgG Antibody (HIT), Serum

Useful For Suggests clinical disorders or settings where the test may be helpful

Detection of IgG antibodies directed against heparin/platelet factor 4 complexes that are implicated in the pathogenesis of immune-mediated type II heparin-induced thrombocytopenia (HIT-II).

 

Clinical picture of HIT type II:

-In patients not previously exposed to heparin

-Decrease in platelet count (thrombocytopenia) of 50% or more from baseline or postoperative peak

-Onset of thrombocytopenia beginning approximately 5 to 10 days after initiation of heparin this may or may not be associated with new or progressive thrombosis in patients treated with heparin

 

Patients previously exposed to heparin (especially within the preceding 100 days), in addition to the above findings, the onset of thrombocytopenia could occur within 24 to 48 hours after reexposure to heparin

Method Name A short description of the method used to perform the test

Enzyme-Linked Immunosorbent Assay (ELISA)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Heparin-PF4 IgG Ab (HIT), S

Aliases Lists additional common names for a test, as an aid in searching

HAT ELISA
Heparin Induced Antibody
Heparin-Dependent Antibody
HIT ELISA
PF4 ELISA