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Test ID: HYOX    
Hyperoxaluria Panel, Urine

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Useful For Suggests clinical disorders or settings where the test may be helpful

Distinguishing between primary and secondary hyperoxaluria

 

Distinguishing between primary hyperoxaluria types 1, 2, and 3

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

Primary hyperoxalurias (PH), classified into types 1, 2, and 3, are genetic disorders of oxalate metabolism characterized by increased urinary excretion of oxalic acid and kidney stone formation.

 

Secondary hyperoxaluria is an acquired condition resulting from either increased intake of dietary oxalate or altered intestinal oxalate absorption.

Highlights

A diagnostic workup in an individual with hyperoxaluria demonstrates increased concentration of oxalate in urinary metabolite screening. If glycolate, glycerate, or 4-hydroxy-2-oxoglutarate is present, a primary hyperoxaluria is indicated.

 

Each type is distinguished from the others based on the urine profile.

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Hyperoxaluria Diagnostic Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Gas Chromatography-Mass Spectrometry (GC-MS)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Hyperoxaluria Panel, U

Aliases Lists additional common names for a test, as an aid in searching

Glycerate
Glycolate
Oxalate
PH1 (Primary Hyperoxaluria Type 1)
PH2 (Primary Hyperoxaluria Type 2)
Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 2 (PH2)
4-hydroxy-2-oxoglutarate
HOG
HOGA1
PH3 (Primary Hyperoxaluria Type 3)
Primary Hyperoxaluria Type 3 (PH3)