Test Catalog

Test ID: SPBX    
Epidermal Nerve Fiber Density Consultation, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Investigation of polyneuropathies

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
SS2PCSpecStain, Grp II, otherNo, (Bill Only)No
COSPCConsult, Outside SlideNo, (Bill Only)No
CUPPCConsult, w/USS ProfNo, (Bill Only)No
CRHPCConsult, w/Comp Rvw of HisNo, (Bill Only)No
MANPCMorph Analysis, NerveNo, (Bill Only)No
LV4RPLevel 4 Gross and Microscopic, RB No, (Bill Only)No
CSPPCConsult, w/Slide PrepNo, (Bill Only)No
EMElectron MicroscopyYesNo
IHPCIIHC InitialNo, (Bill Only)No

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

A battery of enzyme histochemical stains or immunostains are performed; other tests can be performed as indicated at an additional charge.


Wet tissue for consultation: When adequately prepared tissue is provided, routine testing will include: PGP 9.5 immunostain, morphometric analysis, Congo red stain, and hematoxylin and eosin stain. PGP 9.5 reactions cannot be done on previously embedded tissue eg, paraffin blocks, epoxy blocks etc.


Slides and blocks sent for consultation must include PGP 9.5-reacted sections:

Special stains and studies performed on the case should be sent with the case for review. In order to determine an accurate diagnosis, some of these stains or studies may be deemed to warrant repeat testing at an additional charge at the discretion of the reviewing Mayo Clinic neuromuscular pathologist. In addition, testing requested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing Mayo Clinic neuromuscular pathologist. For all consultations, ancillary testing necessary to determine a diagnosis is ordered at the discretion of the Mayo Clinic neuromuscular pathologist. An interpretation, which includes an evaluation of the specimen and determination of a diagnosis, will be provided within a formal pathology report.


See Pathology Consultation Ordering Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Calculation of Epidermal Nerve Fiber Density

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Epidermal Nerve Fiber Density

Aliases Lists additional common names for a test, as an aid in searching

Skin punch biopsy
Small fiber neuropathy