Test ID: HPWET    
Hematopathology Consultation, MCL Embed

Obtaining a rapid, expert opinion for diagnosis of hematologic and non-hematologic diseases using unprocessed bone marrow biopsy specimens referred by the primary pathologist

Obtaining special studies that are not available locally

If a bone marrow pathology consultation is requested, the Mayo Clinic hematopathologists approach the diagnosis in the same way as Mayo Clinic's own in-house cases.

It is the Division of Hematopathology's mission to provide the highest possible level of diagnostic consultative service, trying to balance optimal patient care with a cost-conscious approach to solving difficult diagnostic problems for all patients.

A Mayo Clinic hematopathologist will provide a full bone marrow workup that includes an evaluation of the specimen and determination of a diagnosis provided within a formal pathology report.

Ancillary Testing:

Based on Mayo Clinic-approved algorithms or at a staff hematopathologist's discretion, ancillary testing may be performed to assist in rendering an accurate diagnosis and provide important prognostic information. These test results (eg, cytochemical stains on bone marrow aspirate smear, immunohistochemical stains on bone marrow biopsy or clot sections, chromosome analysis, fluorescence in situ hybridization: FISH, flow cytometry, microarray, molecular and/or next-generation sequencing (NGS) testing) will be reported and billed separately. While reported separately, these results will continue to be considered and referred to in the pathology final interpretation.

If ancillary testing (eg, flow cytometry) is desired by the client outside of this consultation, each test must be ordered separately. Tests ordered outside of the consultation may or may not be integrated into the final pathology report based on the staff hematopathologist's discretion.

If the volume of bone marrow aspirate is limited, prioritization of testing will be determined by the staff hematopathologist. Testing requested or suggested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing staff hematopathologist.

Note: Calls are not routinely made; however, depending on the nature of the case, a call may be placed to the ordering provider or pathologist. These situations include, but are not limited to, a new diagnosis of acute leukemia or aggressive high grade lymphoma. To contact a Mayo Clinic Hematopathologist, call the Hematopathology Communications tech at 507-284-5600.

See Pathology Consultation Ordering Algorithm in Special Instructions.

• Hematopathology Patient Information
• Pathology Consultation Ordering Algorithm
• Bone Marrow Core Biopsy, Clot, and Aspirate Collection Guideline
• Assistance with Bone Marrow Collection