Test Catalog

Test Id : PATHC

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Pathology Consultation

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Overview

Test Catalog

Useful For
Suggests clinical disorders or settings where the test may be helpful

A subspecialty second opinion for a specific pathology question referred by a primary pathologist

Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP synoptics)

 

Obtaining special studies not available locally

 

This test is not intended to be used to obtain a primary diagnosis.

Highlights

Our consultative practice strives to provide the highest quality diagnostic consultative service, balancing optimal patient care with a cost-conscious approach that supports the rapid turnaround time for diagnostic results.

Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test Id Reporting Name Available Separately Always Performed
COSPC Consult, Outside Slide No, (Bill Only) No
CRHPC Consult, w/Comp Rvw of His No, (Bill Only) No
CSPPC Consult, w/Slide Prep No, (Bill Only) No
CUPPC Consult, w/USS Prof No, (Bill Only) No

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This request will be processed as a consultation case. An interpretation, which includes an evaluation of the specimen and determination of a diagnosis, will be provided within a formal pathology report. Second opinion regarding diagnosis will be rendered by staff pathologists, often in consultation with colleagues who have expertise in the appropriate subspecialty areas. Appropriate additional stains and other ancillary testing may be performed in order to render comprehensive assessment. These additional stains/tests ordered will have the results included within the final pathology report and will be at an additional charge.

 

Note: Special stains and studies performed on the case should be sent with the case for review. In order to determine an accurate diagnosis, some of these stains or studies may be deemed to warrant being repeated, at an additional charge, at the reviewing Mayo Clinic pathologist's discretion. In addition, testing requested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing Mayo Clinic pathologist. For all pathology consultations, ancillary testing necessary to determine a diagnosis is ordered at the discretion of the Mayo Clinic pathologist.

 

For more information see Pathology Consultation Ordering Algorithm.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Pathology Consult

Aliases
Lists additional common names for a test, as an aid in searching

Acute Leukemia

Acute Lymphocytic Leukemia-differentiate T from non-T cell forms

Biopsy

Bladder Carcinoma

Bone Marrow Consultation

Breast Carcinoma

Colon Carcinoma

Cytochemical

Dermatopathology Consultation, H and E Slide

Endometrial Carcinoma

Hematopathology Consultation, Slides or Blocks

Pathology, Surgical

Prostate Carcinoma

Renal Cell Carcinoma

Renal Pathology Consultation

Skin Biopsy

Surgical Pathology Consultation, Slides or Blocks

Thyroid Carcinoma

Consultation

Path Consult

Second Opinion

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This request will be processed as a consultation case. An interpretation, which includes an evaluation of the specimen and determination of a diagnosis, will be provided within a formal pathology report. Second opinion regarding diagnosis will be rendered by staff pathologists, often in consultation with colleagues who have expertise in the appropriate subspecialty areas. Appropriate additional stains and other ancillary testing may be performed in order to render comprehensive assessment. These additional stains/tests ordered will have the results included within the final pathology report and will be at an additional charge.

 

Note: Special stains and studies performed on the case should be sent with the case for review. In order to determine an accurate diagnosis, some of these stains or studies may be deemed to warrant being repeated, at an additional charge, at the reviewing Mayo Clinic pathologist's discretion. In addition, testing requested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing Mayo Clinic pathologist. For all pathology consultations, ancillary testing necessary to determine a diagnosis is ordered at the discretion of the Mayo Clinic pathologist.

 

For more information see Pathology Consultation Ordering Algorithm.

Specimen Type
Describes the specimen type validated for testing

MMLDRY

Ordering Guidance

This test is intended for use with dry tissue - blocks and/or slides - only. For test ordering guidance for other specimen types, see Pathology Consultation Ordering Algorithm.

 

If requesting only a peripheral blood smear evaluation, order SPSM / Morphology Evaluation (Special Smear), Blood.

Note: Send only those case specimens for which a Mayo pathologist interpretation is needed.

Shipping Instructions

Attach the green "Attention Pathology" address label included in the kit to the outside of the transport container.

Necessary Information

The following information is required:

 

1. All requisitions must be labeled with:

-Patient name, date of birth, and medical record number

-Name and phone number of the referring pathologist or ordering physician

-Anatomic site and collection date

 

2. All specimens must be labeled with:

-Two patient identifiers (first and last name, date of birth, or medical record number)

-Specimen type and anatomic site

 

3. A preliminary or final pathology report and brief patient history is essential to achieve a consultation fully relevant to the ordering pathologist's needs. If a report is not available, submit the Pathology Consultation Request (T246) with the specimen.

 

4. A specific diagnostic question is required for each specimen/part submitted. Include question in a cover letter or in the requisition notes/comments. For ease of submission, the Pathology Consultation Cover Letter form can be completed and sent with the specimen.

 

5. Additional requirements by case type:

-For Bone consults, pre-operative imaging studies are often required. Either submit on CD or thumb drive with the request.

-For Neuro Pathology consults, clinical and/or radiology imaging should be included if available. Either submit on CD or thumb drive with the request.

-For Bone Marrow consults, include:

1. Recent peripheral blood smear with complete blood cell count (CBC) report

2. Bone marrow biopsy/clot (block and stained slides)

3. Bone marrow aspirate (stained and unstained slides)

4. All pending and final reports for ancillary testing on above specimens

 

All requisition and supporting information must be submitted in English.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Pathology Packaging Kit (T554)

Specimen Type: Tissue: Formalin Fixed Paraffin-embedded blocks, stained slides and/or unstained slides

Note: Submit only pertinent hematoxylin and eosin (H and E) and all special stains relevant to the diagnostic questions for the case. Include positively charged unstained slides and/or a formalin-fixed, paraffin-embedded tissue block if it is anticipated that additional stains or ancillary testing may be necessary.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Pathology Consultation Request (T246)

-Hematopathology/Cytogenetics Test Request (T726)

-Gastroenterology and Hepatology Client Test Request (T728)

-Benign Hematology Test Request (T755)

-Oncology Test Request (T729)

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
MMLDRY Ambient

Useful For
Suggests clinical disorders or settings where the test may be helpful

A subspecialty second opinion for a specific pathology question referred by a primary pathologist

Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP synoptics)

 

Obtaining special studies not available locally

 

This test is not intended to be used to obtain a primary diagnosis.

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This request will be processed as a consultation case. An interpretation, which includes an evaluation of the specimen and determination of a diagnosis, will be provided within a formal pathology report. Second opinion regarding diagnosis will be rendered by staff pathologists, often in consultation with colleagues who have expertise in the appropriate subspecialty areas. Appropriate additional stains and other ancillary testing may be performed in order to render comprehensive assessment. These additional stains/tests ordered will have the results included within the final pathology report and will be at an additional charge.

 

Note: Special stains and studies performed on the case should be sent with the case for review. In order to determine an accurate diagnosis, some of these stains or studies may be deemed to warrant being repeated, at an additional charge, at the reviewing Mayo Clinic pathologist's discretion. In addition, testing requested by the referring physician (immunostains, molecular studies, etc) may not be performed if deemed unnecessary by the reviewing Mayo Clinic pathologist. For all pathology consultations, ancillary testing necessary to determine a diagnosis is ordered at the discretion of the Mayo Clinic pathologist.

 

For more information see Pathology Consultation Ordering Algorithm.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Mayo Clinic in Rochester, MN is staffed by pathologists whose expertise and special interests cover the entirety of pathology-from surgical pathology with all of its respective subspecialty areas, to Hematopathology, Renal Pathology, and Dermatopathology.

 

Consultation services are provided for difficult diagnostic problems. Consultation cases may be sent by a referring pathologist and directed to one of the pathologists who is an expert in the given area or directed more broadly to the subspecialty group. Cases are frequently shared and, sometimes, transferred between the pathologists, as deemed appropriate for the type of case or diagnostic problem encountered. Emphasis is placed on prompt and accurate results. Stained slides and paraffin blocks received are reviewed in conjunction with the clinical history provided, laboratory findings, radiographic findings (if applicable), and sending pathologist's report or letter. If additional special stains or studies are needed, the results are included in the final interpretive report. In some cases, electron microscopy and other special procedures are utilized as required.

 

A variety of ancillary studies are available (eg, cytochemistry, immunohistochemistry, immunofluorescence, electron microscopy, mass spectrometry, cytogenetics, and molecular genetics) to aid in establishing a diagnosis. These ancillary studies are often expensive, labor intensive, and most efficiently utilized and interpreted in the context of the morphologic features.

 

The goal is to provide the highest possible level of diagnostic consultative service, while balancing optimal patient care with a cost-conscious approach to solving difficult diagnostic problems.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

An interpretive report will be provided.

Interpretation
Provides information to assist in interpretation of the test results

Results of the consultation are reported in a formal pathology report that includes a description of ancillary test results (if applicable) and an interpretive comment.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Hematopathology, medical renal pathology, and dermatopathology primary consultation can be provided by separate tests (HPWET / Hematopathology Consultation, MCL Embed; RPCWT / Renal Pathology Consultation, Wet Tissue; DEXT / DermPath Consultation, Wet Tissue). Otherwise, primary interpretation should be performed by a local pathology service and Mayo Clinic pathologists will render a second opinion if requested.

 

Appropriate stained and unstained slides and tissue sampling and fixation is required in order to make a diagnosis on routine stains and on the special stains or studies that may be required.

 

Specific diagnosis may require correlation with clinical information.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

Renshaw AA, Gould EW. Measuring the value of review of pathology material by a second pathologist. Am J Clin Pathol. 2006 May;125(5):737-9. doi: 10.1309/6A0R-AX9K-CR8V-WCG4

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Method Description
Describes how the test is performed and provides a method-specific reference

All requests will be processed as a consultation case first. Special studies will be performed only if deemed to be diagnostically indicated. If the need for enzyme cytochemical stains, immunophenotyping, and/or immunohistochemical stains is anticipated, appropriate specimen requirements should be followed as indicated.

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

4 to 8 days; The final pathology report may be delayed if additional materials are required, or if ancillary testing (up to 21 days) is indicated.

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Material made at Mayo Clinic may be retained at Mayo Clinic indefinitely

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

Not Applicable

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

88321 (if appropriate)

88323 (if appropriate)

88325 (if appropriate)

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
PATHC Pathology Consult 60570-9
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
71038 Interpretation 60570-9
71039 Participated in the Interpretation No LOINC Needed
71040 Report electronically signed by 19139-5
71041 Addendum 35265-8
71042 Material Received 22633-2
71583 Disclaimer 62364-5
71789 Case Number 80398-1

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports