Test Catalog

Test ID: CSFME    
Meningitis/Encephalitis Pathogen Panel, PCR, Spinal Fluid

Useful For Suggests clinical disorders or settings where the test may be helpful

Rapid detection of meningitis and encephalitis caused by:

-Escherichia coli K1 (K1 serotype only)

-Haemophilus influenzae

-Listeria monocytogenes

-Neisseria meningitidis (encapsulated strains only)

-Streptococcus agalactiae (Group B Strep)

-Streptococcus pneumoniae

-Cytomegalovirus (CMV)


-Herpes simplex virus 1 (HSV-1)

-Herpes simplex virus 2 (HSV-2)

-Herpes simplex virus 6 (HHV-6)

-Human parechovirus

-Varicella zoster virus (VZV)

-Cryptococcus neoformans/gattii


This test is not intended for use with CSF collected from indwelling medical devices (eg, CSF shunts).


This test is not recommended as a test of cure.


This test is used to rapidly detect the nucleic acid of 14 of the most common pathogens that cause encephalitis or meningitis.


The FilmArray Meningitis/Encephalitis panel is a multiplex PCR test capable of qualitatively detecting DNA or RNA of 14 pathogens (bacteria, viruses, and yeast) in approximately 1 hour from spinal fluid.


This test is used to diagnose infection caused by Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, cytomegalovirus, enterovirus, herpes simplex virus 1 and 2, human herpesvirus 6, human parechovirus, varicella zoster virus, and Cryptococcus neoformans/gattii.

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Meningitis/Encephalitis Panel Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Multiplex Polymerase Chain Reaction (PCR)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Meningitis Encephalitis Panel, PCR

Aliases Lists additional common names for a test, as an aid in searching

Multiplex PCR
Syndromic panel
Central Nervous System
Spinal fluid
Escherichia coli K1
Haemophilus influenza
Listeria monocytogenes
Neisseria meningitidis
Streptococcus agalactiae (Group B Strep)
Streptococcus pneumoniae
Cytomegalovirus (CMV)
Herpes Simplex Virus 1 (HSV-1)
Herpes Simplex Virus 1 (HSV-2)
Herpes Simplex Virus 6 (HHV-6)
Human Parechovirus
Varicella Zoster Virus (VZV)
Cryptococcus neoformans/gattii