Test Catalog

Test ID: NGAML    
Next-Generation Sequencing, Acute Myeloid Leukemia, 11-Gene Panel, Varies

Useful For Suggests clinical disorders or settings where the test may be helpful

Evaluation of acute myeloid leukemia (AML) using a focused 11-gene panel at the time of diagnosis or possibly at relapsed/refractory disease, to assist in appropriate classification, prognosis, and therapeutic management of patients


Evaluation to determine if a different gene mutation profile is present at the time of AML relapse

Genetics Test Information Provides information that may help with selection of the correct genetic test or proper submission of the test request

This test includes next-generation sequencing to evaluate for the following 11 genes: CEBPA, DNMT3A, FLT3, IDH1, IDH2, KIT, KRAS, NPM1, NRAS, RUNX1, and TP53.


Next-generation sequencing detection of somatic gene mutations, including type, pattern, and distribution, has diagnostic, prognostic, and potential therapeutic implications for patients with hematologic cancers, such as acute myeloid leukemia (AML).


This test enables more accurate classification and prognostic assessment of acute myeloid leukemias (AML).

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

See Targeted Genes Interrogated by Next-Generation Sequencing, Acute Myeloid Leukemia, 11-Gene Panel in Special Instructions for a list of the genes and exons targeted by this assay.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Somatic Mutation Detection by Next-Generation Sequencing (NGS), Hematologic Neoplasms

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Next Gen Sequencing, AML, 11 Gene

Aliases Lists additional common names for a test, as an aid in searching

Next generation sequencing of leukemia
Next Gen Sequencing Test
NGS for acute myeloid leukemia evaluation
NGS hematologic malignancies
Somatic mutation detection by next generation sequencing (NGS), hematologic