Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Detecting and identifying bacteria (including mycobacteria) from normally sterile sources, including synovial fluid; body fluids such as pleural, peritoneal, and pericardial fluids, cerebrospinal fluid (CSF); and both fresh and formalin-fixed paraffin-embedded (FFPE) tissues
This test is not recommended as a test of cure because nucleic acids may persist for long periods of time after successful treatment.
This test is used for detection and identification of bacteria (including mycobacteria) in normally sterile specimens.
This test is optimal for situations in which bacteria (including mycobacteria) are visualized in the specimen but other laboratory methods have failed to yield a diagnosis.
Test ID | Reporting Name | Available Separately | Always Performed |
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ISBA | Bacterial Ident by Sequencing | No, (Bill Only) | No |
PCRID | Identification by PCR | No, (Bill Only) | No |
ISNGS | Ident by Next Generation Sequencing | No, (Bill Only) | No |
If polymerase chain reaction (PCR) testing is negative, no sequencing is performed, and the test is resulted as negative.
If PCR testing is positive, sequencing is performed. Strong positive results are first submitted to Sanger sequencing, which can yield results in as few as 4 days. Weak positive results, or Sanger sequencing results that are mixed, are submitted to next-generation sequencing (ie, targeted metagenomics testing).
The following algorithms are available in Special Instructions:
-Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology
16S Ribosomal RNA Gene Polymerase Chain Reaction (PCR) followed by Sequencing