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Test ID: CMAMT    
Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue

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Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis of congenital copy number changes in products of conception, including aneuploidy (ie, trisomy or monosomy) and structural abnormalities

 

Diagnosing chromosomal causes for fetal death

 

Determining recurrence risk of future pregnancy losses

 

Determining the size, precise breakpoints, gene content, and any unappreciated complexity of abnormalities detected previously by other methods such as conventional chromosome and fluorescence in situ hybridization (FISH) studies

 

Determining if apparently balanced abnormalities identified by previous conventional chromosome studies have cryptic imbalances, since a proportion of such rearrangements that appear balanced at the resolution of a chromosome study are actually unbalanced when analyzed by higher-resolution chromosomal microarray

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Hematoxylin and eosin stain review of the paraffin-embedded sample is performed to identify the area of fetal tissue prior to DNA extraction and microarray analysis.

 

See Frequently Asked Questions: Cytogenetic Testing of Products of Conception by Chromosomal Microarray Analysis in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Chromosomal Microarray

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Chromosomal Microarray, POC, FFPE

Aliases Lists additional common names for a test, as an aid in searching

aCGH
Array CGH
Array Comparative Genomic Hybridization
Oligonucleotide Array
Oligo Array
Single Nucleotide Polymorphism (SNP) Array
Whole Genome Array
Microarray
Molecular Karyotype
OncoScan
Congenital Array
Constitutional Array
Absence of Heterozygosity (AOH)
Fetal Demise
Miscarriage
Pregnancy Loss
Paraffin Embedded Tissue Array
Paraffin Embedded POC Array