Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Identifying solid tumors that may respond to targeted therapies by simultaneously assessing for rearrangements involving targeted regions of the NTRK1, NTRK2, and NTRK3 genes resulting in fusion transcripts
This test is not useful for hematologic malignancies.
This test uses next-generation sequencing to identify rearrangements (fusions) involving targeted regions of the NTRK1, NTRK2, and NTRK3 genes.
The assay was designed to detect the most common NTRK gene fusions and novel gene fusion partners in the targeted gene regions. See NTRK RNA Targeted Gene Fusions table in Special Instructions for details.
Of note, this test is performed to evaluate rearrangements (fusions) within solid tumor samples. This test is not intended for use for hematological malignancies.
This test evaluates formalin-fixed, paraffin-embedded tumor slides from patients with advanced solid tumors for rearrangements (fusions) involving targeted regions of the NTRK1, NTRK2, and NTRK3 genes to identify candidates for targeted therapy. Current data suggests that solid tumors with NTRK rearrangements may be sensitive to multikinase inhibitors.
Test ID | Reporting Name | Available Separately | Always Performed |
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SLIRV | Slide Review in MG | No, (Bill Only) | Yes |
When this test is ordered, slide review will always be performed at an additional charge.
Polymerase Chain Reaction (PCR)-Based Next-Generation Sequencing (NGS)