Referred Tests
| Web: | mayocliniclabs.com |
|---|---|
| Email: | mcl@mayo.edu |
| Telephone: | 800-533-1710 |
| International: | +1 855-379-3115 |
| Values are valid only on day of printing. | |
Test ID: MAC1
Autoimmune Myelopathy Evaluation, Spinal Fluid
Useful For 
Suggests clinical disorders or settings where the test may be helpful
Evaluating patients with suspected autoimmune myelopathy, myelitis, paraneoplastic myelopathy in spinal fluid specimens
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MCI1 | Autoimmune Myelopathy Interp, CSF | No | Yes |
| AMPHC | Amphiphysin Ab, CSF | No | Yes |
| AGN1C | Anti-Glial Nuclear Ab, Type 1 | No | Yes |
| ANN1C | Anti-Neuronal Nuclear Ab, Type 1 | No | Yes |
| ANN2C | Anti-Neuronal Nuclear Ab, Type 2 | No | Yes |
| ANN3C | Anti-Neuronal Nuclear Ab, Type 3 | No | Yes |
| CRMWC | CRMP-5-IgG Western Blot, CSF | Yes | Yes |
| CRMC | CRMP-5-IgG, CSF | No | Yes |
| DPPIC | DPPX Ab IFA, CSF | No | Yes |
| GD65C | GAD65 Ab Assay, CSF | Yes | Yes |
| GFAIC | GFAP IFA, CSF | No | Yes |
| GL1IC | mGluR1 Ab IFA, CSF | No | Yes |
| NMOFC | NMO/AQP4 FACS, CSF | Yes | Yes |
| PCTRC | Purkinje Cell Cytoplasmc Ab Type Tr | No | Yes |
| PCA1C | Purkinje Cell Cytoplasmic Ab Type 1 | No | Yes |
| PCA2C | Purkinje Cell Cytoplasmic Ab Type 2 | No | Yes |
Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AMPCC | AMPA-R Ab CBA, CSF | No | No |
| AMPIC | AMPA-R Ab IF Titer Assay, CSF | No | No |
| ABLTC | Amphiphysin Western Blot, CSF | No | No |
| DPPCC | DPPX Ab CBA, CSF | No | No |
| DPPTC | DPPX Ab IFA Titer, CSF | No | No |
| GABCC | GABA-B-R Ab CBA, CSF | No | No |
| GABIC | GABA-B-R Ab IF Titer Assay, CSF | No | No |
| GFACC | GFAP CBA, CSF | No | No |
| GFATC | GFAP IFA Titer, CSF | No | No |
| GL1CC | mGluR1 Ab CBA, CSF | No | No |
| GL1TC | mGluR1 Ab IFA Titer, CSF | No | No |
| NMDCC | NMDA-R Ab CBA, CSF | No | No |
| NMDIC | NMDA-R Ab IF Titer Assay, CSF | No | No |
| NMOTC | NMO/AQP4 FACS Titer, CSF | No | No |
| WBNC | Paraneoplas Autoantibody WBlot,CSF | No | No |
Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.
If indirect immunofluorescence assay (IFA) (ANN1C, ANN2C, AGN1C, PCA1C, PCA2C, AMPHC) is indeterminate, then WBNC is performed at an additional charge.
Western Blot: Native neuronal antigens: performed to confirm neuronal nuclear and cytoplasmic antibody specificities when IF screening is uninterpretable.
If IFA patterns suggest amphiphysin antibody, then amphiphysin Western blot is performed at an additional charge.
If IFA pattern suggest NMDA-R antibody, then NMDA-R antibody cell-binding assay (CBA) and NMDA-R titer are performed at an additional charge.
If IFA pattern suggest AMPA-R antibody, then AMPA-R antibody CBA and AMPA-R titer are performed at an additional charge.
If IFA pattern suggest GABA-B-R antibody, then GABA-B-R antibody CBA and GABA-B-R titer are performed at an additional charge.
If IFA pattern suggest DPPX antibody, then DPPX antibody CBA and DPPX IFA titer are performed at an additional charge.
If IFA pattern suggest mGluR1 antibody, then mGluR1antibody CBA and mGluR1 IFA titer are performed at an additional charge.
If IFA pattern suggest GFAP antibody, then GFAP antibody CBA and GFAP IFA titer are performed at an additional charge.
If NMO/AQP4-IgG FACS screen assay requires further investigation, then NMO/AQP4-IgG FACS titration assay is performed at an additional charge.
See Autoimmune Myelopathy Evaluation Algorithm-Spinal Fluid in Special Instructions.
Special Instructions Library of PDFs including pertinent information and forms related to the test
Method Name A short description of the method used to perform the test
ANN1C, ANN2C, ANN3C, AGN1C, AMPHC, CRMC, PCA1C, PCA2C, PCTRC, DPPIC, GL1IC, GFAIC, AMPIC, DPPTC, GABIC, GFATC, GL1TC, NMDIC: Indirect Immunofluorescence Assay (IFA)
GD65C: Immunoprecipitation Assay (IPA)
ABLTC, CRMWC, WBNC: Western Blot (WB)
NMOFC, NMOTC: Flow Cytometry (FACS)
AMPCC, DPPCC, GABCC, GL1CC, NMDCC: Cell-binding Assay (CBA)
NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.
Reporting Name Lists a shorter or abbreviated version of the Published Name for a test
Aliases Lists additional common names for a test, as an aid in searching
Neuromyelitis optica
Anti-GFAP