Test Catalog

Test ID: TOSU    
Targeted Opioid Screen, Random, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Determining compliance or identifying illicit opioid drug use using urine specimens


This test is not intended for employment-related testing.


This test uses high-resolution accurate mass spectrometry to identify 33 different opioids and/or metabolites where immunoassays are not adequate.


This test offers lower detection limits than previous Mayo Clinic Laboratories-offered screens.


This test has the ability to detect "spiked" samples.

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
LPPOList prescribed opioidsNoYes
TOPSUTargeted Opioid Screen, UNoYes

Method Name A short description of the method used to perform the test

Liquid Chromatography-Tandem Mass Spectrometry, High-Resolution Accurate Mass (LC-MS/MS HRAM)

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Targeted Opioid Screen, U

Aliases Lists additional common names for a test, as an aid in searching

6-monoacetylmorphine (heroin metabolite)
Buprenorphine (Buprenex, Suboxone)
Codeine (Tylenol #3)
Codeine-6-beta-glucuronide (codeine metabolite)
Dihydrocodeine(hydrocodone metabolite)
EDDP (Methadone metabolite)
Fentanyl (Actiq, Duragesic, Fentora)
Hydrocodone (Lortab, Norco, Vicodin)
Hydromorphone (Dilaudid, Exalgo)
Hydromorphone-3-beta-glucuronide (hydromorphone metabolite)
Meperidine (Demerol)
Methadone (Dolophine)
Methadone metabolite (EDDP)
Morphine (Avinza, Kadian, MS Contin)
Morphine-6-beta-glucuronide (morphine metabolite
N-desmethyltapentadol (Tapentadol metabolite)
Naloxone (Narcan)
Naloxone-3-beta-glucuronide (Naloxone metabolite)
Norbuprenorphine (Buprenorphine metabolite)
Norbuprenorphine glucuronide (Buprenorphine metabolite)
Norfentanyl (fentanyl metabolite)
Norhydrocodone (hydrocodone metabolite)
Normeperidine (Meperidine metabolite)
Noroxycodone (oxycodone metabolite)
Noroxymorphone (Oxymorphone metabolite)
Norpropoxyphene (propoxyphene metabolite)
O-desmethyltramadol (Tramadol metabolite)
Oxycodone (Endocet, Percocet, Oxycontin)
Oxymorphone (Numorphan, Opana)
Oxymorphone-3-beta-glucuronide (Oxymorphone metabolite)
Propoxyphene (Darvon, Darvocet)
Tapentadol (Nucynta)
Tapentadol-beta-glucuronide (Tapentadol metabolite)
Tramadol (Tradol, Ultram, Ultracet)